Academic Journal

The value of PCT, IL-6, and CRP in the early diagnosis and evaluation of COVID-19

التفاصيل البيبلوغرافية
العنوان: The value of PCT, IL-6, and CRP in the early diagnosis and evaluation of COVID-19
المؤلفون: Y.-Z. Zhou, X.-B. Teng, M.-F. Han, J.-F. Shi, C.-X. Li, X.-H. Zhang, D.-Y. Hou, L.-L. Yang
المصدر: European Review for Medical and Pharmacological Sciences, Vol 25 (2021)
بيانات النشر: Verduci Editore
سنة النشر: 2021
المجموعة: Directory of Open Access Journals: DOAJ Articles
مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950
الوصف: OBJECTIVE: The aim of the present study was to assess the value of inflammatory factors procalcitonin (PCT), interleukin 6 (IL-6), and C-reactive protein (CRP) in the early diagnosis and evaluation of novel coronavirus pneumonia (COVID-19). MATERIALS AND METHODS: The data of 140 patients with pneumonia in our hospital, including 70 who had COVID-19 and 70 who had community-acquired pneumonia (CAP), were statistically analyzed. The levels of PCT, IL-6, and CRP were measured and statistically analyzed to determine the differences between the two groups. The differences in the COVID-19 group were analyzed after subgrouping into the ordinary type, severe type, and critical type. RESULTS: The PCT and CRP levels in the COVID-19 group were statistically lower than those in the CAP group (p < 0.05), but IL-6 was not statistically different between the two groups (p > 0.05). Statistically significant differences existed in IL-6 and CRP when comparing the COVID-19 subgroups of the critical type, severe type, and ordinary type (p < 0.05). However, there was no clinical meaning in the evaluation of the difference in PCT levels among the three subgroups with COVID-19. CONCLUSIONS: PCT and CRP could be used as indicators in the differentiation between COVID-19 and CAP, but IL-6 was of little significance in the differentiation. The higher the IL-6 and CRP, the more severe the condition of COVID-19 might be.
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 1128-3602
Relation: https://www.europeanreview.org/wp/wp-content/uploads/1097-1100.pdf; https://doaj.org/toc/1128-3602; https://doaj.org/article/b629067927f04809bc7845247150df38
الاتاحة: https://doaj.org/article/b629067927f04809bc7845247150df38
رقم الانضمام: edsbas.A1E47C5D
قاعدة البيانات: BASE