Academic Journal
أعرض في EDS

Increased Erythrocyte Aggregation As An Indicator For An Aggressive Clinical Course In Behcet'S Disease: A Prospective Study

التفاصيل البيبلوغرافية
العنوان: Increased Erythrocyte Aggregation As An Indicator For An Aggressive Clinical Course In Behcet'S Disease: A Prospective Study
المؤلفون: Demiroglu, H, Yalcin, S, Buyukasik, Y, Ozcebe, OI, Dundar, S
المساهمون: İç Hastalıkları
بيانات النشر: British Med Journal Publ Group
سنة النشر: 1998
المجموعة: Hacettepe University Institutional Repository
مصطلحات موضوعية: Rheumatology
الوصف: Objective-Changes in blood rheology, especially increased erythrocyte aggregation (EA) might play an important part in the development of arterial and venous thrombotic lesions. A prospective study was designed to evaluate EA in patients with Behcet's disease (BD) and to see if this parameter is predictive for the future development of vascular complications, such as deep vein thrombosis of various organ systems and uveitis. Methods-EA was measured by a photometric Myrenne aggregometer in 38 patients with ED at the time of initial diagnosis and in 40 age and sex matched healthy controls (HC). Results-During a median follow up period of 13.5 months, 13 patients developed vascular-ocular complications (eight deep vein thrombosis, nine uveitis, and four both deep vein thrombosis and uveitis). Patients were further divided into two groups: ED-a with mucocutaneous symptoms and arthritis only; BD-b with associated vascular-ocular complications. EA values at high shear rate (M) and at low shear rate (M1) were compared among the groups. Conclusion-PA values at M and Mi were significantly higher in BD-b than ED-a and HC (p<0.001). These results suggest that determination of EA rates might be useful to identify subgroups who are Likely candidates for developing vascular-ocular complications in ED and management of factors known to affect blood rheology might be beneficial.
نوع الوثيقة: article in journal/newspaper
وصف الملف: text/plain; application/pdf
اللغة: English
تدمد: 0003-4967
Relation: Annals Of The Rheumatic Diseases; https://doi.org/10.1136/ard.57.11.694; http://hdl.handle.net/11655/15135; 57; 11; 694; 696
DOI: 10.1136/ard.57.11.694
الاتاحة: http://hdl.handle.net/11655/15135
https://doi.org/10.1136/ard.57.11.694
Rights: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.9F04E2A
قاعدة البيانات: BASE
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