Academic Journal
Diagnostic ability of inner macular layers to discriminate early glaucomatous eyes using vertical and horizontal B-scan posterior pole protocols
| العنوان: | Diagnostic ability of inner macular layers to discriminate early glaucomatous eyes using vertical and horizontal B-scan posterior pole protocols |
|---|---|
| المؤلفون: | Bambo, M.P., Cameo, B., Hernandez, R., Fuentemilla, E., Güerri, N., Ferrandez, B., Polo, V., Larrosa, J.M., Pablo, L.E., Garcia-Martin, E. |
| سنة النشر: | 2018 |
| المجموعة: | Digital Repository of University of Zaragoza (ZAGUAN) |
| الوصف: | Purpose To evaluate the diagnostic ability of macular ganglion cell (mGCL) and macular retinal nerve fiber (mRNFL) layers, to detect early glaucomatous eyes, using the new segmentation software of Spectralis optical coherence tomography (OCT) device (Heidelberg Engineering). Methods A total of 83 eyes from 83 subjects were included in this observational, prospective cross-sectional study: 43 healthy controls and 40 early primary open-angle glaucoma (POAG) patients. All participants were examined using the Horizontal and Vertical Posterior Pole protocols, and the peripapillary RNFL (pRNFL) protocol of Spectralis OCT device. The new automated retinal segmentation software was applied to horizontal and vertical macular B-scans to determine mGCL and mRNFL thicknesses in each one of the 9 sectors of the Early Treatment Diagnostic Retinopathy Study circle. Thickness of each layer was compared between groups, and the sectors with better area under the receiver operating characteristic curve (AUC) were identified. Results mGCL was significantly thinner in the POAG group, especially in outer and inner temporal sectors (p<0.001); and mRNFL was significantly thinner in the POAG group in the outer inferior and the outer superior sector (p<0.001). Diagnostic accuracy of inner macular layers was good, and in general mGCL was superior to mRNFL. pRNFL obtained the best diagnostic capability (AUC, 0.886). Horizontal and vertical Posterior Pole protocols performed similarly. Conclusions Inner macular layers using either horizontal or vertical B-scans, especially temporal sectors of mGCL, have good diagnostic capability to differentiate early glaucomatous eyes from control eyes; however, pRNFL has the highest diagnostic sensitivity for glaucoma detection. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://zaguan.unizar.es/record/74863 |
| DOI: | 10.1371/journal.pone.0198397 |
| الاتاحة: | http://zaguan.unizar.es/record/74863 https://doi.org/10.1371/journal.pone.0198397 |
| Rights: | by ; http://creativecommons.org/licenses/by/3.0/es/ |
| رقم الانضمام: | edsbas.9E195834 |
| قاعدة البيانات: | BASE |
| ResultId |
1 |
|---|---|
| Header |
edsbas BASE edsbas.9E195834 882 3 Academic Journal academicJournal 881.885437011719 |
| PLink |
https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsbas&AN=edsbas.9E195834&custid=s6537998&authtype=sso |
| FullText |
Array
(
[Availability] => 0
)
Array ( [0] => Array ( [Url] => http://zaguan.unizar.es/record/74863# [Name] => EDS - BASE [Category] => fullText [Text] => View record in BASE [MouseOverText] => View record in BASE ) ) |
| Items |
Array
(
[Name] => Title
[Label] => Title
[Group] => Ti
[Data] => Diagnostic ability of inner macular layers to discriminate early glaucomatous eyes using vertical and horizontal B-scan posterior pole protocols
)
Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => <searchLink fieldCode="AR" term="%22Bambo%2C+M%2EP%2E%22">Bambo, M.P.</searchLink><br /><searchLink fieldCode="AR" term="%22Cameo%2C+B%2E%22">Cameo, B.</searchLink><br /><searchLink fieldCode="AR" term="%22Hernandez%2C+R%2E%22">Hernandez, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Fuentemilla%2C+E%2E%22">Fuentemilla, E.</searchLink><br /><searchLink fieldCode="AR" term="%22Güerri%2C+N%2E%22">Güerri, N.</searchLink><br /><searchLink fieldCode="AR" term="%22Ferrandez%2C+B%2E%22">Ferrandez, B.</searchLink><br /><searchLink fieldCode="AR" term="%22Polo%2C+V%2E%22">Polo, V.</searchLink><br /><searchLink fieldCode="AR" term="%22Larrosa%2C+J%2EM%2E%22">Larrosa, J.M.</searchLink><br /><searchLink fieldCode="AR" term="%22Pablo%2C+L%2EE%2E%22">Pablo, L.E.</searchLink><br /><searchLink fieldCode="AR" term="%22Garcia-Martin%2C+E%2E%22">Garcia-Martin, E.</searchLink> ) Array ( [Name] => DatePubCY [Label] => Publication Year [Group] => Date [Data] => 2018 ) Array ( [Name] => Subset [Label] => Collection [Group] => HoldingsInfo [Data] => Digital Repository of University of Zaragoza (ZAGUAN) ) Array ( [Name] => Abstract [Label] => Description [Group] => Ab [Data] => Purpose To evaluate the diagnostic ability of macular ganglion cell (mGCL) and macular retinal nerve fiber (mRNFL) layers, to detect early glaucomatous eyes, using the new segmentation software of Spectralis optical coherence tomography (OCT) device (Heidelberg Engineering). Methods A total of 83 eyes from 83 subjects were included in this observational, prospective cross-sectional study: 43 healthy controls and 40 early primary open-angle glaucoma (POAG) patients. All participants were examined using the Horizontal and Vertical Posterior Pole protocols, and the peripapillary RNFL (pRNFL) protocol of Spectralis OCT device. The new automated retinal segmentation software was applied to horizontal and vertical macular B-scans to determine mGCL and mRNFL thicknesses in each one of the 9 sectors of the Early Treatment Diagnostic Retinopathy Study circle. Thickness of each layer was compared between groups, and the sectors with better area under the receiver operating characteristic curve (AUC) were identified. Results mGCL was significantly thinner in the POAG group, especially in outer and inner temporal sectors (p<0.001); and mRNFL was significantly thinner in the POAG group in the outer inferior and the outer superior sector (p<0.001). Diagnostic accuracy of inner macular layers was good, and in general mGCL was superior to mRNFL. pRNFL obtained the best diagnostic capability (AUC, 0.886). Horizontal and vertical Posterior Pole protocols performed similarly. Conclusions Inner macular layers using either horizontal or vertical B-scans, especially temporal sectors of mGCL, have good diagnostic capability to differentiate early glaucomatous eyes from control eyes; however, pRNFL has the highest diagnostic sensitivity for glaucoma detection. ) Array ( [Name] => TypeDocument [Label] => Document Type [Group] => TypDoc [Data] => article in journal/newspaper ) Array ( [Name] => Format [Label] => File Description [Group] => SrcInfo [Data] => application/pdf ) Array ( [Name] => Language [Label] => Language [Group] => Lang [Data] => English ) Array ( [Name] => NoteTitleSource [Label] => Relation [Group] => SrcInfo [Data] => http://zaguan.unizar.es/record/74863 ) Array ( [Name] => DOI [Label] => DOI [Group] => ID [Data] => 10.1371/journal.pone.0198397 ) Array ( [Name] => URL [Label] => Availability [Group] => URL [Data] => http://zaguan.unizar.es/record/74863<br />https://doi.org/10.1371/journal.pone.0198397 ) Array ( [Name] => Copyright [Label] => Rights [Group] => Cpyrght [Data] => by ; http://creativecommons.org/licenses/by/3.0/es/ ) Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsbas.9E195834 ) |
| RecordInfo |
Array
(
[BibEntity] => Array
(
[Identifiers] => Array
(
[0] => Array
(
[Type] => doi
[Value] => 10.1371/journal.pone.0198397
)
)
[Languages] => Array
(
[0] => Array
(
[Text] => English
)
)
[Titles] => Array
(
[0] => Array
(
[TitleFull] => Diagnostic ability of inner macular layers to discriminate early glaucomatous eyes using vertical and horizontal B-scan posterior pole protocols
[Type] => main
)
)
)
[BibRelationships] => Array
(
[HasContributorRelationships] => Array
(
[0] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Bambo, M.P.
)
)
)
[1] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Cameo, B.
)
)
)
[2] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Hernandez, R.
)
)
)
[3] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Fuentemilla, E.
)
)
)
[4] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Güerri, N.
)
)
)
[5] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Ferrandez, B.
)
)
)
[6] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Polo, V.
)
)
)
[7] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Larrosa, J.M.
)
)
)
[8] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Pablo, L.E.
)
)
)
[9] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Garcia-Martin, E.
)
)
)
)
[IsPartOfRelationships] => Array
(
[0] => Array
(
[BibEntity] => Array
(
[Dates] => Array
(
[0] => Array
(
[D] => 01
[M] => 01
[Type] => published
[Y] => 2018
)
)
[Identifiers] => Array
(
[0] => Array
(
[Type] => issn-locals
[Value] => edsbas
)
[1] => Array
(
[Type] => issn-locals
[Value] => edsbas.oa
)
)
)
)
)
)
)
|
| IllustrationInfo |