Academic Journal
ETIOLOGICAL STRUCTURE OF VIRAL RESPIRATORY DISEASES IN ADULT PATIENTS WITH BRONCHIAL ASTHMA EXACERBATION AND CHRONICAL BRONCHIOLITIS OBLITERANS ; ЭТИОЛОГИЧЕСКАЯ СТРУКТУРА ВИРУСНЫХ РЕСПИРАТОРНЫХ ЗАБОЛЕВАНИЙ У ВЗРОСЛЫХ ПАЦИЕНТОВ С ОБОСТРЕНИЕМ БРОНХИАЛЬНОЙ АСТМЫ И ХРОНИЧЕСКИМ БРОНХИОЛИТОМ С ОБЛИТЕРАЦИЕЙ
| العنوان: | ETIOLOGICAL STRUCTURE OF VIRAL RESPIRATORY DISEASES IN ADULT PATIENTS WITH BRONCHIAL ASTHMA EXACERBATION AND CHRONICAL BRONCHIOLITIS OBLITERANS ; ЭТИОЛОГИЧЕСКАЯ СТРУКТУРА ВИРУСНЫХ РЕСПИРАТОРНЫХ ЗАБОЛЕВАНИЙ У ВЗРОСЛЫХ ПАЦИЕНТОВ С ОБОСТРЕНИЕМ БРОНХИАЛЬНОЙ АСТМЫ И ХРОНИЧЕСКИМ БРОНХИОЛИТОМ С ОБЛИТЕРАЦИЕЙ |
|---|---|
| المؤلفون: | Krivitskaya V.Z., Sominina A.A., Petrova M.A., Amosova I.V., Mayorovа V.G., Pisareva M.M., Buzitskaya J.V., Grudinin M.P., Golovanova A.K., Petrova E.R., Kovaleva L.F., Kiseleva E.A. |
| المصدر: | Russian Journal of Infection and Immunity; Vol 5, No 1 (2015); 45-54 ; Инфекция и иммунитет; Vol 5, No 1 (2015); 45-54 ; 2313-7398 ; 2220-7619 ; 10.15789/2220-7619-2015-1 |
| بيانات النشر: | SPb RAACI |
| سنة النشر: | 2015 |
| المجموعة: | Russian Journal of Infection and Immunity (Infektsiya i immunitet) / Инфекция и иммунитет |
| مصطلحات موضوعية: | respiratory infections, viruses, adult patients, bronchial asthma, chronical bronchiolitis, obliteration, virus-specific antibodies, респираторные инфекции, вирусы, взрослые пациенты, бронхиальная астма, хронический бронхиолит, облитерация, вирусспецифические антитела |
| الوصف: | Exacerbation of bronchial asthma (BA) and common deterioration of health during chronic bronchiolitis obliterans (ChBO) are associated with viral infections in adults in 64 and 83% respectively. Mixed virus-viral associations were shown in 21–25% of cases. Respiratory syncytial infections were diagnosed with the highest frequency (50%) in patients with BA. Influenza A(H1N1)pdm09 and adenoviral infections dominated in persons with ChBO in 50 and 42% of cases, respectively. Response of virus-specific IgG in patients with BA and ChBO indicates the acute course of influenza A(H1N1)pdm09 (63% of seroconversions). There were no reactions of IgG which is specific to respiratory syncytial virus in 75% of cases and to adenovirus in 83% of cases, that is the risk factor for occurrence of latent/persistent infection. Presence of structural components of respiratory syncytial virus in the upper respiratory tract had been revealed in three patients with asthma within at least 21–28 days. Respiratory syncytial viral infections and pandemic influenza A(H1N1) pdm09 in patients with BA and ChBO are characterized by the presence of an allergic component, which is indicated by the high levels of virus-specific IgE in blood. An adenoviral infection, in contrast, has no such peculiarity. ; Обострение бронхиальной астмы (БА) и общее ухудшение самочувствия при хроническом облитерирующем бронхиолите (ХБО) ассоциировано у взрослых пациентов с вирусными инфекциями в 64 и 83% соответственно. Смешанные вирус-вирусные ассоциации были показаны в 21–25% случаев. При БА с наибольшей частотой (50%) диагностирована респираторно-синцитиальная вирусная инфекция. У больных ХБО превалировал грипп, вызванный вирусом A(H1N1)pdm09 (50%), и аденовирусная инфекция (42%). Ответ на инфекцию вирусспецифических IgG у больных БА и ХБО свидетельствует об остром течении гриппа A (63% сероконверсий). Реакция IgG, специфичных к респираторно-синцитиальному вирусу и аденовирусу, отсутствовала у инфицированных больных в 75 и 83% соответственно, что является ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Russian |
| Relation: | https://iimmun.ru/iimm/article/view/273/224; https://iimmun.ru/iimm/article/view/273 |
| DOI: | 10.15789/2220-7619-2015-1-45-54 |
| الاتاحة: | https://iimmun.ru/iimm/article/view/273 https://doi.org/10.15789/2220-7619-2015-1-45-54 |
| Rights: | Copyright (c) 2015 Krivitskaya V.Z., Sominina A.A., Petrova M.A., Amosova I.V., Mayorovа V.G., Pisareva M.M., Buzitskaya J.V., Grudinin M.P., Golovanova A.K., Petrova E.R., Kovaleva L.F., Kiseleva E.A. ; https://creativecommons.org/licenses/by/4.0 |
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