Academic Journal
Hippomanin a from acetone extract of Phyllanthus urinaria inhibited HSV‐2 but not HSV‐1 infection in vitro
| العنوان: | Hippomanin a from acetone extract of Phyllanthus urinaria inhibited HSV‐2 but not HSV‐1 infection in vitro |
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| المؤلفون: | Yang, Chien‐Min, Cheng, Hua‐Yew, Lin, Ta‐Chen, Chiang, Lien‐Chai, Lin, Chun‐Ching |
| المصدر: | Phytotherapy Research ; volume 21, issue 12, page 1182-1186 ; ISSN 0951-418X 1099-1573 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2007 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Phyllanthus urinaria Linnea (Euphorbiaceae) is a commonly used traditional medicinal plant in oriental countries and has been reported to possess various biological activities. Previously, the acetone extract and some pure compounds from P. urinaria were found to suppress herpes simplex virus (HSV). In this study, another two pure compounds were isolated from acetone extract of P. urinaria and were tested for their in vitro anti‐HSV‐1 and HSV‐2 activities. The results showed that hippomanin A impeded HSV‐2 but not HSV‐1 infection. Corilagin, however, inhibited neither HSV‐1 nor HSV‐2 replication. The similarity between corilagin and hippomanin A in structure, but difference in antiviral activity, therefore, merit further investigation. Copyright © 2007 John Wiley & Sons, Ltd. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/ptr.2232 |
| الاتاحة: | https://doi.org/10.1002/ptr.2232 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fptr.2232 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.2232 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.83B64158 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/ptr.2232 |
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