Academic Journal
Microenvironment-responsive nanomedicines:a promising direction for tissue regeneration
| العنوان: | Microenvironment-responsive nanomedicines:a promising direction for tissue regeneration |
|---|---|
| المؤلفون: | Xiong, Yuan, Mi, Bo Bin, Shahbazi, Mohammad Ali, Xia, Tian, Xiao, Jun |
| المصدر: | Xiong , Y , Mi , B B , Shahbazi , M A , Xia , T & Xiao , J 2024 , ' Microenvironment-responsive nanomedicines : a promising direction for tissue regeneration ' , Military Medical Research , vol. 11 , 69 . https://doi.org/10.1186/s40779-024-00573-0 |
| سنة النشر: | 2024 |
| المجموعة: | University of Groningen research database |
| مصطلحات موضوعية: | Bone, Immunomodulation, Microenvironment, Nanomedicine, Repair, Tissue regeneration |
| الوصف: | Severe tissue defects present formidable challenges to human health, persisting as major contributors to mortality rates. The complex pathological microenvironment, particularly the disrupted immune landscape within these defects, poses substantial hurdles to existing tissue regeneration strategies. However, the emergence of nanobiotechnology has opened a new direction in immunomodulatory nanomedicine, providing encouraging prospects for tissue regeneration and restoration. This review aims to gather recent advances in immunomodulatory nanomedicine to foster tissue regeneration. We begin by elucidating the distinctive features of the local immune microenvironment within defective tissues and its crucial role in tissue regeneration. Subsequently, we explore the design and functional properties of immunomodulatory nanosystems. Finally, we address the challenges and prospects of clinical translation in nanomedicine development, aiming to propose a potent approach to enhance tissue regeneration through synergistic immune modulation and nanomedicine integration. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| DOI: | 10.1186/s40779-024-00573-0 |
| الاتاحة: | https://hdl.handle.net/11370/0ea45f60-b3a1-4ca3-98e8-5f9528d9e41f https://research.rug.nl/en/publications/0ea45f60-b3a1-4ca3-98e8-5f9528d9e41f https://doi.org/10.1186/s40779-024-00573-0 https://pure.rug.nl/ws/files/1145068541/s40779-024-00573-0.pdf http://www.scopus.com/inward/record.url?scp=85206960882&partnerID=8YFLogxK |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.7E91E10B |
| قاعدة البيانات: | BASE |
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