Academic Journal
Comparison of disease profiles and three-month outcomes of patients with neurological disorders with and without COVID-19: An ambispective cohort study
| العنوان: | Comparison of disease profiles and three-month outcomes of patients with neurological disorders with and without COVID-19: An ambispective cohort study |
|---|---|
| المؤلفون: | Kanchana S Pillai, Deepti Vibha, Pranjal Gupta, Pachipala Sudheer, Biswamohan Mishra, Rahul S Oinam, Ayush Mohan, Kamalesh Tayade, Padma Srivastava, Manjari Tripathi, Achal K Srivastava, Rohit Bhatia, Roopa Rajan, Awadh K Pandit, Rajesh K Singh, Arunmozhimaran Elavarasi, Ayush Agarwal, Anu Gupta, Animesh Das, Divya M Radhakrishnan, Bhargavi Ramanujam, Kapil D Soni, Richa Aggarwal, Naveet Wig, Anjan Trikha |
| المصدر: | Annals of Indian Academy of Neurology, Vol 25, Iss 2, Pp 218-223 (2022) |
| بيانات النشر: | Wolters Kluwer Medknow Publications |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | ambispective cohort study, covid-19 neurology, in-hospital mortality, modified rankin scale, 3- months follow-up, Neurology. Diseases of the nervous system, RC346-429 |
| الوصف: | Objective: Neurological emergencies saw a paradigm shift in approach during the coronavirus disease-2019 (COVID-19) pandemic with the challenge to manage patients with and without COVID-19. We aimed to compare the various neurological disorders and 3 months outcome in patients with and without SARS-CoV-2 infection. Methods: In an ambispective cohort study design, we enrolled patients with and without SARS CoV-2 infection coming to a medical emergency with neurological disorders between April 2020 and September 2020. Demographic, clinical, biochemical, and treatment details of these patients were collected and compared. Their outcomes, both in-hospital and at 3 months were assessed by the modified Rankin Scale (mRS). Results: Two thirty-five patients (235) were enrolled from emergency services with neurological disorders. Of them, 81 (34.5%) were COVID-19 positive. The mean (SD) age was 49.5 (17.3) years, and the majority of the patients were male (63.0%). The commonest neurological diagnosis was acute ischemic stroke (AIS) (43.0%). The in-hospital mortality was higher in the patients who were COVID-19 positive (COVID-19 positive: 29 (35.8%) versus COVID-19 negative: 12 (7.8%), P value: <0.001). The 3 months telephonic follow-up could be completed in 73.2% of the patients (142/194). Four (12.1%) deaths occurred on follow-up in the COVID-19 positive versus fifteen (13.8%) in the COVID-19 negative patients (P value: 1.00). The 3-month mRS was worse in the COVID-19 positive group (P value <0.001). However, this was driven by higher in-hospital morbidity and mortality in COVID-19 positive patients. Conclusion: Patients with neurological disorders presenting with COVID-19 infection had worse outcomes, including in-hospital and 3 months disability. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0972-2327 1998-3549 |
| Relation: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2022;volume=25;issue=2;spage=218;epage=223;aulast=Pillai; https://doaj.org/toc/0972-2327; https://doaj.org/toc/1998-3549; https://doaj.org/article/1e441436cbdb43deb757bd9b49825de6 |
| DOI: | 10.4103/aian.aian_602_21 |
| الاتاحة: | https://doi.org/10.4103/aian.aian_602_21 https://doaj.org/article/1e441436cbdb43deb757bd9b49825de6 |
| رقم الانضمام: | edsbas.7C81B045 |
| قاعدة البيانات: | BASE |
Full Text Finder كن أول من يترك تعليقا!