Academic Journal
Assessment of Sleep among Patients with Chronic Liver Disease: Association with Quality of Life
| العنوان: | Assessment of Sleep among Patients with Chronic Liver Disease: Association with Quality of Life |
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| المؤلفون: | Oana-Mihaela Plotogea, Gina Gheorghe, Madalina Stan-Ilie, Gabriel Constantinescu, Nicolae Bacalbasa, Simona Bungau, Camelia Cristina Diaconu |
| المصدر: | Journal of Personalized Medicine, Vol 11, Iss 1387, p 1387 (2021) |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2021 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | sleep, chronic liver disease, quality of life, Medicine |
| الوصف: | The present study aims to assess the sleep characteristics and health-related quality of life (HRQOL) among patients with chronic liver diseases (CLDs), as well as the relationship between them. We conducted a prospective cross-sectional study, over a period of eight months, on patients with CLDs. Sleep was assessed by subjective tools (self-reported validated questionnaires), semi-objective methods (actigraphy), and HRQOL by using the 36-Item Short Form Survey (SF-36) and Chronic Liver Disease Questionnaire (CLDQ). The results indicated that 48.21% of patients with CLDs had a mean Pittsburgh Sleep Quality Index (PSQI) score higher than five, suggestive of poor sleep; 39.29% of patients had a mean Epworth Sleepiness Scale (ESS) score ≥11, indicative of daytime sleepiness. Actigraphy monitoring showed that patients with cirrhosis had significantly more delayed bedtime hours and get-up hours, more awakenings, and more reduced sleep efficacy when compared to pre-cirrhotics. The CLDQ and SF-36 questionnaire scores were significantly lower in cirrhotics compared to pre-cirrhotics within each domain. Moreover, we identified significant correlations between the variables from each questionnaire, referring to HRQOL and sleep parameters. In conclusion, sleep disturbances are commonly encountered among patients with CLDs and are associated with impaired HRQOL. This is the first study in Romania that assesses sleep by actigraphy in a cohort of patients with different stages of CLD. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2075-4426 |
| Relation: | https://www.mdpi.com/2075-4426/11/12/1387; https://doaj.org/toc/2075-4426; https://doaj.org/article/871eb0eb44bd49ada34614fc3ff18ec7 |
| DOI: | 10.3390/jpm11121387 |
| الاتاحة: | https://doi.org/10.3390/jpm11121387 https://doaj.org/article/871eb0eb44bd49ada34614fc3ff18ec7 |
| رقم الانضمام: | edsbas.78D66FD8 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20754426 |
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| DOI: | 10.3390/jpm11121387 |