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Epidemiological and microbiological analysis of ventilator-associated pneumonia patients in a public teaching hospital

التفاصيل البيبلوغرافية
العنوان: Epidemiological and microbiological analysis of ventilator-associated pneumonia patients in a public teaching hospital
المؤلفون: Silva Júnior,João Manoel da, Rezende,Ederlon, Guimarães,Thaís, Campos,Edvaldo V. dos, Magno,Luiz André, Consorti,Lívia, Pereira,Renata Andréa Pietro, Nascimento,Maria de Lourdes, Mendonça,João Silva de
المصدر: Brazilian Journal of Infectious Diseases v.11 n.5 2007
بيانات النشر: Brazilian Society of Infectious Diseases
سنة النشر: 2007
المجموعة: SciELO Brazil (Scientific Electronic Library Online)
مصطلحات موضوعية: Ventilator-associated pneumonia, epidemiology, microbiology
الوصف: Ventilator-associated pneumonia (VAP) is the most commonly-acquired infection in patients in intensive care units. We analyzed epidemiological and microbiological characteristics and the outcome, in a cohort of critically-ill patients with confirmed diagnosis of VAP. All patients who had been on mechanical ventilation (MV) for more than 48 hours were included in our study; material collection for microbiological analysis was done within the first 24 hours after beginning treatment or after changing antibiotics. There were 55/265 (20.7%) VAP cases diagnosed, at a rate of 21.6 episodes per 1,000 days of mechanical ventilation. Mean age of the patients was 66 years, with a mean APACHE II score of 26.7 + 7.0; male patients were more prevalent. The mortality rates in the intensive care unit (ICU) and during the hospital stay were 71% and 80%, respectively. MV duration in patients with VAP was 17 (range 3-43) days and among patients who had not developed VAP, 6 (2-32) days (p < 0.0001). 98.2% of the samples were positive, with a high prevalence of Gram-negative bacteria, mainly Acinetobacter calcoaceticus. Risk factors for death included age, MV duration and surgery. VAP incidence in this sample of critically-ill patients was high, with a high mortality rate. Control and prevention strategies based on continuing education of healthcare workers, developed by a multidisciplinary team, should be encouraged to minimize morbimortality of this infection.
نوع الوثيقة: article in journal/newspaper
وصف الملف: text/html
اللغة: English
الاتاحة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000500009
رقم الانضمام: edsbas.788F633E
قاعدة البيانات: BASE
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