Academic Journal
Treatment of recalcitrant atrophic non-union of the humeral shaft with BMP-7, autologous bone graft and hydroxyapatite pellets
| العنوان: | Treatment of recalcitrant atrophic non-union of the humeral shaft with BMP-7, autologous bone graft and hydroxyapatite pellets |
|---|---|
| المؤلفون: | CATERINI, ROBERTO, POTENZA, VITO, IPPOLITO, ERNESTO, FARSETTI, PASQUALE |
| المساهمون: | Caterini, R, Potenza, V, Ippolito, E, Farsetti, P |
| سنة النشر: | 2016 |
| المجموعة: | Universitá degli Studi di Roma "Tor Vergata": ART - Archivio Istituzionale della Ricerca |
| مصطلحات موضوعية: | BMP-7, Humeral non-union, OP-1, bone morphogenetic protein, humeral shaft, Settore MED/33 - MALATTIE APPARATO LOCOMOTORE |
| الوصف: | Recalcitrant humeral non-union is a disabling condition that is extremely difficult to treat. The use of BMP-7 has been proposed to improve bone healing. This is a report of the results obtained in 12 patients with recalcitrant humeral non-union treated using stable fixation with a long locking compression plate and BMP-7, autologous bone graft and hydroxyapatite pellets applied at the non-union site. Patients had up to three surgical attempts at non-union healing prior to our treatment. The average time from the initial fracture to our surgery was 5.2 years. Average follow-up was 5.3 years. At follow-up, non-union had healed in all patients by an average of 7.3 months. All the patients were very satisfied with their final results, despite a restricted range of motion of the elbow and a moderate muscular atrophy, which was frequently observed. Our study shows that BMP-7 associated with autologous bone grafting and hydroxyapatite pellets after stable fixation is an effective adjuvant to stimulate bone healing in the treatment of recalcitrant humeral non-union. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/27507544; info:eu-repo/semantics/altIdentifier/wos/WOS:000390540300013; volume:47; issue:SUPPL.4; firstpage:S71; lastpage:S77; journal:INJURY; http://hdl.handle.net/2108/171997; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84995677709 |
| DOI: | 10.1016/j.injury.2016.07.044 |
| الاتاحة: | http://hdl.handle.net/2108/171997 https://doi.org/10.1016/j.injury.2016.07.044 |
| رقم الانضمام: | edsbas.78883C01 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.injury.2016.07.044 |
|---|