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Evaluation of the Effectiveness of Three Different Treatment Regimens in Patients Receiving Helicobacter Pylori First-Line Therapy ; Helikobakter Pylori Birinci Basamak Tedavisi Alan Hastalarda Üç Farklı Tedavi Rejiminin Etkinliğinin Değerlendirilmesi

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العنوان: Evaluation of the Effectiveness of Three Different Treatment Regimens in Patients Receiving Helicobacter Pylori First-Line Therapy ; Helikobakter Pylori Birinci Basamak Tedavisi Alan Hastalarda Üç Farklı Tedavi Rejiminin Etkinliğinin Değerlendirilmesi
المؤلفون: EKİN, Nazım, EBİK, Berat, BACAKSIZ, Ferhat
المصدر: Volume: 18, Issue: 1 100-103 ; 1304-9623 ; 1309-4025 ; Harran Üniversitesi Tıp Fakültesi Dergisi
بيانات النشر: Harran Üniversitesi
Harran University
سنة النشر: 2021
المجموعة: DergiPark Akademik (E-Journals)
مصطلحات موضوعية: Helicobacter pylori,eradication,triple therapy,quadruple therapy, Helikobakter pilori,eradikasyon,üçlü tedavi,dörtlü tedavi
الوصف: Background: Bl The aim of our study is to determine the Helicobacter pylori (Hp) eradication success rates of the most commonly used Hp treatment regimens.Materials and Methods: Patients who diagnosed with Hp during upper gastrointestinal endoscopy and received control endoscopic biopsy after treatment between 2016 and 2020 were retrospectively evaluated. Patients were divided into three groups according to their treatment regimens: Group 1, lansoprazole 30 mg 2x1, clarithromycin 500 mg 2x1, amoxicillin 1000 mg 2x1 14 days; Group 2, lansoprazole 30 mg 2x1, bismuth subsalicylate 262 mg 4x1, clarithromycin 500 mg 2x1, amoxicillin 1000 mg 2x1 14 days; and Group 3, lansoprazole 30 mg 2x1, bismuth subsalicylate 262 mg 4x1, metronidazole 500 mg 3x1, tetracycline 500 mg 4x1 14 days. The success rates of three groups were evaluated.Results: Sixty patients with a mean age of 42.8±15.17 years were included in the study. The mean age of groups 1,2 and 3 were 40.05 ± 15.33, 42.86 ± 15.90, and 46.23 ± 14.14, respectively, and there was no statistically significant difference among groups. Hp eradication was achieved in 57.6% (34/60) of the patients included in the study after eradication treatment. HP eradication rates in groups 1, 2 and 3 were 50%, 52.2% and 66.7%, respectively. There was no statistically significant difference among the groups in terms of success rates.Conclusions: In this study, we concluded that classical triple therapy, classic triple treatment with added bismuth and quadruple therapy with bismuth may not be appropriate used in Turkey due to high antibiotic resistance and low eradication rates. New treatment regimens need to be developed to treat Helicobacter pylori. ; Amaç: Bu çalışmadaki amacımız en sık kullanılan Helikobakter pylori (Hp) tedavi rejimlerinin HP eradikasyon başarı oranlarını saptamaktır.Materyal ve Metod: 2016 – 2020 yılları arasında üst gastrointestinal sistem endoskopisi sırasında Helikobakter pylori pozitif saptanan ve eradikasyon tedavisi sonrası kontrol endoskopik biyopsi alınan ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: Turkish
Relation: https://dergipark.org.tr/tr/download/article-file/1385369; https://dergipark.org.tr/tr/pub/hutfd/issue/61987/822754
DOI: 10.35440/hutfd.822754
الاتاحة: https://dergipark.org.tr/tr/pub/hutfd/issue/61987/822754
https://doi.org/10.35440/hutfd.822754
رقم الانضمام: edsbas.6C69323
قاعدة البيانات: BASE
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