Academic Journal
Maternal Reassurance, Satisfaction, and Anxiety after First-Trimester Screening for Aneuploidies: Comparison between Contingent Screening and Universal Cell-Free DNA Testing
| العنوان: | Maternal Reassurance, Satisfaction, and Anxiety after First-Trimester Screening for Aneuploidies: Comparison between Contingent Screening and Universal Cell-Free DNA Testing |
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| المؤلفون: | Tramontano, Anna Luna, Marano, Ilaria, Orlandi, Giuliana, Angelino, Antonio, Rivieccio, Maria, Fulgione, Caterina, Maruotti, Giuseppe Maria, Saccone, Gabriele, De Vita, Gabriella, Guida, Maurizio, Sarno, Laura |
| المساهمون: | Tramontano, Anna Luna, Marano, Ilaria, Orlandi, Giuliana, Angelino, Antonio, Rivieccio, Maria, Fulgione, Caterina, Maruotti, Giuseppe Maria, Saccone, Gabriele, De Vita, Gabriella, Guida, Maurizio, Sarno, Laura |
| سنة النشر: | 2024 |
| المجموعة: | IRIS Università degli Studi di Napoli Federico II |
| مصطلحات موضوعية: | aneuploidy, cell-free DNA, contingent screening, first-trimester screening, maternal anxiety, maternal reassurance, maternal satisfaction |
| الوصف: | Background: This study aims to evaluate maternal reassurance, satisfaction, and anxiety after two different strategies for the first-trimester screening for aneuploidies. Methods: Patients between 11 + 3 and 13 + 6 weeks of gestation attending the first-trimester screening at Department of Mother and Child, University Hospital Federico II, Naples, Italy have been recruited and randomly allocated to contingent screening or universal cell-free fetal DNA testing (cffDNA). Questionnaires to measure reassurance, satisfaction, and anxiety have been filled twice: (Q1) after randomization and (Q2) after receiving results. Anxiety was measured by an Italian-version short form of the state scale of the Spielberger State-Trait Anxiety Inventory (STAI); child-related anxiety was measured by the 11-item Pregnancy-Related Anxiety Questionnaire-Revised Regardless of Parity (PRAQ-R2 scale); fear of bearing a physically or mentally handicapped child was measured considering only four items (item 4, 9, 10, and 11) of the PRAQ-R2 scale. Results: 431 patients were recruited: 205 (49%) were randomized in the contingent screening arm, 226 (51%) in the cfDNA arm. Maternal reassurance, satisfaction, and anxiety were not different in the two groups. Conclusion: A contingent screening for aneuploidies in the first trimester seems able to ensure the same maternal reassurance and satisfaction as a cfDNA analysis in the low-risk population and to not affect maternal anxiety. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/wos/WOS:001245674900001; volume:14; issue:11; journal:DIAGNOSTICS; https://hdl.handle.net/11588/968104 |
| DOI: | 10.3390/diagnostics14111198 |
| الاتاحة: | https://hdl.handle.net/11588/968104 https://doi.org/10.3390/diagnostics14111198 |
| رقم الانضمام: | edsbas.63DC4C39 |
| قاعدة البيانات: | BASE |
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