Academic Journal
Pain assessment in fentanyl-propofol combination: two dosage levels ; Оценка боли при применении комбинации фентанил-пропофол: два уровня дозировки
| العنوان: | Pain assessment in fentanyl-propofol combination: two dosage levels ; Оценка боли при применении комбинации фентанил-пропофол: два уровня дозировки |
|---|---|
| المؤلفون: | A. A. Sahib, Q. A. Yaqoob, M. A.Z. Sasaa, T. K. Atabi, M. R. Ahmed, A. M. Radeef |
| المصدر: | Messenger of ANESTHESIOLOGY AND RESUSCITATION; Том 20, № 4 (2023); 40-45 ; Вестник анестезиологии и реаниматологии; Том 20, № 4 (2023); 40-45 ; 2541-8653 ; 2078-5658 |
| بيانات النشر: | NEW TERRA Publishing House |
| سنة النشر: | 2023 |
| المجموعة: | Messenger of ANESTHESIOLOGY AND RESUSCITATION / Вестник анестезиологии и реаниматологии |
| مصطلحات موضوعية: | фентанил, propofol, assessment, general anesthesia, fentanyl, пропофол, оценка, общая анестезия |
| الوصف: | Background. In the field of intravenous anesthesia, propofol is widely utilized as an induction agent. However, Propofol injection pain is a frequent adverse event that may result in discomfort for patients. Various strategies have been investigated to prevent or alleviate this pain, considering the presence of opioid receptors in the primary afferent nerve endings of peripheral tissues, which suggests a potential role of opioids in mitigating propofol-induced pain. Fentanyl, a short-acting pure opioid agonist commonly used for systemic analgesia during intraoperative and postoperative periods, has been found to possess peripherally mediated analgesic properties within its clinical dosage range. Therefore, the objective of this study was to evaluate the efficacy of a low dose of fentanyl in the fentanyl-propofol combination for reducing propofol injection pain.The objective of our study was to evaluate and compare the efficacy of two distinct doses of fentanyl in mitigating the pain associated with propofol injection.Materials and methods. The study enrolled 90 patients classified as ASA I–II who were scheduled for elective surgery. The study spanned over 4 months, from November 2022 to April 2023, and included patients aged 19 to 65 years. Patients were divided into three groups, each comprising 30 patients. The control group received only 5 ml (50 mg) of propofol. The group M1 received only 5 ml of a mixture of fentanyl and propofol, prepared with 20 ml (200 mg) of propofol and 2 ml (100 μg) of fentanyl, while the group M2 received only 5 ml of a mixture of fentanyl and propofol, prepared with 20 ml (200 mg) of propofol and 4 ml (200 μg) of fentanyl, at an injection speed of 0.5 ml/s. After 10 seconds of medication, patients were asked a standard question about the comfort of the injection, and a verbal rating scale (VRS) was used to assess propofol injection pain. Anesthesia induction was then continued following standard protocols. Statistical significance was set at p < 0.05 for all analyses.Results. The ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://www.vair-journal.com/jour/article/view/831/651; Ambesh S.P., Dubey P.K., Sinha P.K. Ondansetron pretreatment to alleviate pain on propofol injection. Anesthesia and Analgesia, 1999, vol. 89, no. 1, pp. 197–199. Doi:10.1097/00000539-199907000-00035.; Barker P., Langton J.A. Effect of prior administration of cold saline on pain during propofol injection. Anaesthesia, 1991, vol. 46, no. 12 , pp. 1069–1070. Doi:10.1111/j.1365-2044.1991.tb09927.x.; Basaranoglu G., Erden V., Delatioglu H. Reduction of pain on injection ofpropofol: A comparison of fentanyl with remifentanil. Anesth Analg., 2002, vol. 94, pp. 1040–1041. Doi:10.1097/00000539-200204000-00053. 4. Cheong Mi A. Ephedrine reduces the pain from propofol injection. Anesthesia and Analgesia, 2002, vol. 95, no. 5, pp. 1293–1296. Doi:10.1097/00000539- 200211000-00035.; Eriksson M., Englesson S., Niklasson F. et al. Effect of lignocaine and pH on propofol-induced pain. Br J Anaesth., 1997, vol. 78, pp. 502–506. Doi:10.1093/bja/78.5.502.; Helmers J.H., Kraaijenhagen R.J., Leeuwen L.V. et al. Reduction of pain on injection caused by propofol. Can J Anaesth., 1990, vol. 37, pp. 267–268. Doi:10.1007/BF03005485.; King S.Y., Davis F.M., Wells J.E. et al. Lidocaine for the prevention of pain due to injection of propofol. Anesth Analg., 1992, vol. 74, pp. 246–249. Doi:10.1213/00000539-199202000-00013.; Kizilcik N., Ferdi Menda F., Bilgen S. et al. Effect of fentanyl-Propofol mixture on propofol injection pain: a randomized clinical trial. Korean J Anesthesiol., 2015, vol. 68, no. 6, pp. 556–560. Doi:10.4097/kjae.2015.68.6.556.; Koo S.-W., Cho S.-J., Kim Y.R. et al. Small dose ketamine reduces the pain of propofol injection. Anesthesia and Analgesia, 2006, vol. 103, no. 6, pp. 1444–1447. Doi:10.1213/01.ane.0000243334.83816.53.; Mangar D., Holak E.J. A tourniquet at 50 mmHg followed by intravenous lidocaine diminishes hand pain associated with propofol injection. Anesthesia and Analgesia, 1992, vol. 74, pp. 250–252. Doi:10.1213/00000539-199202000-00014.; Pang W.W., Mok M.S., Huang S. et al. The analgesic effect of fentanyl, morphine, meperidine, and lidocaine in the peripheral veins: A comparative study. Anesth Analg, 1998, vol. 86, pp. 382–386. Doi:10.1097/00000539-1 99802000-00031.; Picard P., Tramèr M.R. Prevention of pain on injection with propofol: A quantitative systematic review. Anesth Analg, 2000, vol. 90, pp. 963–969. Doi:10.1097/00000539-200004000-00035.; Scott R.P., Saunders D.A., Norman J. Propofol: clinical strategies for preventing the pain of injection. Anesthesia, 1988, vol. 43, pp. 492–494. Doi:10.1111/j.1365-2044.1988.tb06641.x.; Silva L.M., Braz L.G., Módolo N.S. Emergence agitation in pediatric anesthesia: current features. J. Pediatr (Rio J)., 2008, vol. 84, pp. 107–13. Doi:10.2223/JPED.1763.; Smithburger P.L., Patel M.K. Pharmacologic Considerations surrounding sedation, delirium, and sleep in critically ill adults: a narrative review. J Pharm Pract., 2019 , vol. 32, no. 3, pp. 271–291. Doi:10.1177/0897190019840120.; Smith I., White P.F., Nathanson M. et al. Propofol: an update on its clinical uses. Anesthesiology, 1994, vol. 81, pp. 1005–1043.; Stark R.D., Binks S.M., Dutka V.N. et al. A review of the safety and tolerance of propofol (‘Diprivan’). Postgraduate Medical Journal, 1985, vol. 61, no. 5, pp. 152–156. PMID: 3877284.; Stewart J.T., Warren F.W., Maddox F.C. et al. The stability of remifentanil hydrochloride and propofol mixtures in polypropylene syringes and polyvinylchloride bags at 22 degrees-24 degrees C. Anesth Analg., 2000, vol. 90, pp. 1450–1451. Doi:10.1097/00000539-200006000-00037.; Zhang Q., Yu Y., Lu Y. et al. Systematic review and meta-analysis of propofol versus barbiturates for controlling refractory status epilepticus. BMC Neurol., 2019, vol. 19, no. 1, pp. 55. Doi:10.1186/s12883-019-1281-y.; Wagner D.S., Yap J.M., Bradley K.M. et al. Assessing parent’s preferences for the avoidance of undesirable anesthesia side effects in their children undergoing surgical procedures. Paediatr Anaesth., 2007, vol. 17, pp. 1035–1042. Doi:10.1111/j.1460-9592.2007.02261.x.; https://www.vair-journal.com/jour/article/view/831 |
| DOI: | 10.24884/2078-5658-2022-20-4-40-45 |
| الاتاحة: | https://www.vair-journal.com/jour/article/view/831 https://doi.org/10.24884/2078-5658-2022-20-4-40-45 |
| Rights: | Authors who publish with this journal agree to the following terms:Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). ; Авторы, публикующие в данном журнале, соглашаются со следующим:Авторы сохраняют за собой авторские права на работу и предоставляют журналу право первой публикации работы на условиях лицензии Creative Commons Attribution License, которая позволяет другим распространять данную работу с обязательным сохранением ссылок на авторов оригинальной работы и оригинальную публикацию в этом журнале.Авторы сохраняют право заключать отдельные контрактные договорённости, касающиеся не-эксклюзивного распространения версии работы в опубликованном здесь виде (например, размещение ее в институтском хранилище, публикацию в книге), со ссылкой на ее оригинальную публикацию в этом журнале.Авторы имеют право размещать их работу в сети Интернет (например в институтском хранилище или персональном сайте) до и во время процесса рассмотрения ее данным журналом, так как это может привести к продуктивному обсуждению и большему количеству ссылок на данную работу (См. The Effect of Open Access). |
| رقم الانضمام: | edsbas.63B5218 |
| قاعدة البيانات: | BASE |
كن أول من يترك تعليقا!