Academic Journal
Polymyalgia rheumatica and giant cell arteritis-three challenges-consequences of the vasculitis process, osteoporosis, and malignancy:A prospective cohort study protocol
| العنوان: | Polymyalgia rheumatica and giant cell arteritis-three challenges-consequences of the vasculitis process, osteoporosis, and malignancy:A prospective cohort study protocol |
|---|---|
| المؤلفون: | Emamifar, Amir, Hess, Søren, Gerke, Oke, Hermann, Anne Pernille, Laustrup, Helle, Hansen, Per Syrak, Thye-Rønn, Peter, Marcussen, Niels, Svendstrup, Frank, Gildberg-Mortensen, Rannveig, Bang, Jacob Christian, Farahani, Ziba Ahangarani, Chrysidis, Stavros, Toftegaard, Pia, Andreasen, Rikke Asmussen, le Greves, Sebastian, Andersen, Hanne Randi, Olsen, Rudolf Nezlo, Hansen, Inger Marie Jensen |
| المصدر: | Emamifar , A , Hess , S , Gerke , O , Hermann , A P , Laustrup , H , Hansen , P S , Thye-Rønn , P , Marcussen , N , Svendstrup , F , Gildberg-Mortensen , R , Bang , J C , Farahani , Z A , Chrysidis , S , Toftegaard , P , Andreasen , R A , le Greves , S , Andersen , H R , Olsen , R N & Hansen , I M J 2017 , ' Polymyalgia rheumatica and giant cell arteritis-three challenges-consequences of the vasculitis process, .... |
| سنة النشر: | 2017 |
| المجموعة: | University of Southern Denmark: Research Output / Syddansk Universitet |
| مصطلحات موضوعية: | fluorodeoxyglucose, giant cell arteritis, osteoporosis and malignancy, polymyalgia rheumatica, positron emission tomography/computed tomography, temporal artery biopsy, vascular stiffness, vasculitis |
| الوصف: | INTRODUCTION: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are common inflammatory conditions. The diagnosis of PMR/GCA poses many challenges since there are no specific diagnostic tests. Recent literature emphasizes the ability of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) to assess global disease activity in inflammatory diseases. 18F-FDG PET/CT may lead to the diagnosis at an earlier stage than conventional imaging and may also assess response to therapy. With respect to the management of PMR/GCA, there are 3 significant areas of concern as follows: vasculitis process/vascular stiffness, malignancy, and osteoporosis. METHODS AND ANALYSIS: All patients with suspected PMR/GCR referred to the Rheumatology section of Medicine Department at Svendborg Hospital, Denmark. The 4 separate studies in the current protocol focus on: the association of clinical picture of PMR/GCA with PET findings; the validity of 18F-FDG PET/CT scan for diagnosis of PMR/GCA compared with temporal artery biopsy; the prevalence of newly diagnosed malignancies in patients with PMR/GCA, or PMR-like syndrome, with the focus on diagnostic accuracy of 18F-FDG PET/CT scan compared with conventional workup (ie, chest X-ray/abdominal ultrasound); and the impact of disease process, and also steroid treatment on bone mineral density, body composition, and vasculitis/vascular stiffness in PMR/GCA patients. ETHICS AND DISSEMINATION: The study has been approved by the Regional Ethics Committee of the Region of Southern Denmark (identification number: S-20160098) and Danish Data Protection Agency (J.nr 16/40522). Results of the study will be disseminated via publications in peer-reviewed journals, and presentation at national and international conferences. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://portal.findresearcher.sdu.dk/da/publications/5b39f24a-ad10-41d9-a38d-dfadc728e202 |
| DOI: | 10.1097/MD.0000000000007297 |
| الاتاحة: | https://portal.findresearcher.sdu.dk/da/publications/5b39f24a-ad10-41d9-a38d-dfadc728e202 https://doi.org/10.1097/MD.0000000000007297 https://findresearcher.sdu.dk/ws/files/125251635/Emamifar_2017_Polymyalgia_rheumatica_and_giant_cell_arteritis.pdf |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.574729EA |
| قاعدة البيانات: | BASE |
كن أول من يترك تعليقا!