Image1.PDF

التفاصيل البيبلوغرافية
العنوان: Image1.PDF
المؤلفون: Petra Schwendner, Maria Bohmeier, Petra Rettberg, Kristina Beblo-Vranesevic, Frédéric Gaboyer, Christine Moissl-Eichinger, Alexandra K. Perras, Pauline Vannier, Viggó T. Marteinsson, Laura Garcia-Descalzo, Felipe Gómez, Moustafa Malki, Ricardo Amils, Frances Westall, Andreas Riedo, Euan P. Monaghan, Pascale Ehrenfreund, Patricia Cabezas, Nicolas Walter, Charles Cockell
سنة النشر: 2018
المجموعة: Frontiers: Figshare
مصطلحات موضوعية: Microbiology, Microbial Genetics, Microbial Ecology, Mycology, sodium chloride, magnesium sulfate, metabolome, compatible solutes, stress response
الوصف: Growth in sodium chloride (NaCl) is known to induce stress in non-halophilic microorganisms leading to effects on the microbial metabolism and cell structure. Microorganisms have evolved a number of adaptations, both structural and metabolic, to counteract osmotic stress. These strategies are well-understood for organisms in NaCl-rich brines such as the accumulation of certain organic solutes (known as either compatible solutes or osmolytes). Less well studied are responses to ionic environments such as sulfate-rich brines which are prevalent on Earth but can also be found on Mars. In this paper, we investigated the global metabolic response of the anaerobic bacterium Yersinia intermedia MASE-LG-1 to osmotic salt stress induced by either magnesium sulfate (MgSO 4 ) or NaCl at the same water activity (0.975). Using a non-targeted mass spectrometry approach, the intensity of hundreds of metabolites was measured. The compatible solutes L-asparagine and sucrose were found to be increased in both MgSO 4 and NaCl compared to the control sample, suggesting a similar osmotic response to different ionic environments. We were able to demonstrate that Yersinia intermedia MASE-LG-1 accumulated a range of other compatible solutes. However, we also found the global metabolic responses, especially with regard to amino acid metabolism and carbohydrate metabolism, to be salt-specific, thus, suggesting ion-specific regulation of specific metabolic pathways.
نوع الوثيقة: still image
اللغة: unknown
Relation: https://figshare.com/articles/figure/Image1_PDF/5926942
DOI: 10.3389/fmicb.2018.00335.s001
الاتاحة: https://doi.org/10.3389/fmicb.2018.00335.s001
https://figshare.com/articles/figure/Image1_PDF/5926942
Rights: CC BY 4.0
رقم الانضمام: edsbas.5095903
قاعدة البيانات: BASE