Academic Journal
Fabrication of Poly(ε-Caprolactone), Hydrophilic and β-Tricalcium Phosphate Layer- by -Layer Nanofibrous Scaffolds for Tissue Engineering
| العنوان: | Fabrication of Poly(ε-Caprolactone), Hydrophilic and β-Tricalcium Phosphate Layer- by -Layer Nanofibrous Scaffolds for Tissue Engineering |
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| المؤلفون: | M. Sohrabi, M. Abbasi, M. M Ansar |
| المصدر: | Journal of Advanced Materials in Engineering, Vol 38, Iss 1, Pp 23-35 (2019) |
| بيانات النشر: | Isfahan University of Technology |
| سنة النشر: | 2019 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | scaffold, layer- by -layer electrospinning, poly(ε-caprolactone), β-tricalcium phosphate, tissue engineering, Materials of engineering and construction. Mechanics of materials, TA401-492 |
| الوصف: | In this study, using biodegradable polymers, nanofiberouse scaffolds were fabricated from the layer-by-layer electrospinning method, including two layer that poly (ε-caprolactone), polyvinylpyrrolidone deposited at first layer and poly (ε-caprolactone), polyvinyl alcohol , β-tricalcium phosphate at latter. After prepration of scaffolds, scanning electron microscopy (SEM), swelling, porosity, mechanical properties and biodegradability behavior in buffered saline phosphate solution were studied. The results confirmed the bioactivity and suitable mechanical properties of the layer-by-layer scaffold. The swelling increase with the addition of hydrophilic polymers and reache 811 ± 214 % in the layer-by-layer scaffold, which reveald a significant difference compared to pure PCL. The MTT test on the layer-by-layer scaffold, after 3, 5 and 7 days of rats bone marrow stem cells (rMSC) culture, showed the cell viability of above 80% moreover, cells morphology on the scafold indicated the optimal compatibility of cells on the scaffold. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | Persian |
| تدمد: | 2251-600X 2423-5733 |
| Relation: | http://jame.iut.ac.ir/article-1-980-en.html; https://doaj.org/toc/2251-600X; https://doaj.org/toc/2423-5733; https://doaj.org/article/29b437935fea463a834dc6cb2a5f7a11 |
| الاتاحة: | https://doaj.org/article/29b437935fea463a834dc6cb2a5f7a11 |
| رقم الانضمام: | edsbas.2B4E5FB9 |
| قاعدة البيانات: | BASE |
| تدمد: | 2251600X 24235733 |
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