Academic Journal
Kronik karaciğer hastalıklarında karaciğerde Helicobacter türlerinin araştırılması
| العنوان: | Kronik karaciğer hastalıklarında karaciğerde Helicobacter türlerinin araştırılması |
|---|---|
| المؤلفون: | Serap Evran, Ulus Salih Akarca, Hilmi Mete, Çiğdem Dinçer, Arzu Özmüş, Koray Tuncer, Nevin Yılmaz, Yücel Batur, Burcu Okutucu |
| سنة النشر: | 2003 |
| المجموعة: | Ege University Institutional Repository |
| مصطلحات موضوعية: | Gastroenteroloji ve Hepatoloji |
| الوصف: | Helicobacter pylori is the major etiologic agent in gastritis and duodenal ulcer. Helicobacter pylori and some other Helicobacter species have been found in extragastric tissues as well. Some reports suggested a relation between Helicobater infection and various liver diseases, such as liver cancer, and primary biliary cirrhosis. Aim: to investigate the genetic elements of Helicobacter pylori and other Helicobacter species in liver tissues of the patients with various liver diseases by PCR. Materials and Methods: a part of the urease gene of Helicobacter pylori, and 16S ribosomal DNA of Helicobacter species were determined from the liver tissues of patients with chronic liver disease by PCR. Results: 185 patients with various liver disease (45 had crip-togenic liver disease, 30 had chronic HBV infection, 21 HCV infection, 17 steatosis hepatis, 15 primary biliary cirrhosis and 12 had nonalcoholic steatohepatitis, and 45 other liver diseases) were included in the study. Only 1 patient with PBC and autoimmune hepatitis overlap syndrome had Helicobacter 16S ribosomal DNA in her liver tissue. None of the patients was found to be positive for the PCR of H. pylori urease gene. Conclusions: In this study, genetic elements of Helicobacter species were not detected in the liver tissues of the patients with chronic liver diseases. These results suggested that Helicobacter infections in the liver have almost no role in the pathogenesis of chronic liver diseases in our population. ; Helicobacter pylori gastrit ve duodenum ülserinin en önemli sebebidir. Bunun yanında Helicobacter pylori ve diğer bazı Helicobacter türlerine mide dışı dokularda da rastlanmaktadır. Karaciğer kanseri ve primer biliyer siroz gibi çeşitli karaciğer hastalıklarında da Helicobacter türlerinin rolü olabileceğine dair çalışmalar yayınlanmıştır. Amaç: Bu çalışmada çeşitli karaciğer hastalıklarında karaciğer dokusunda Helicobacter pylori ve diğer Helicobacter türlerinin varlığının araştırılması planlanmıştır. Materyal ve Metod: Farklı etyolojilere sahip ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | Turkish |
| تدمد: | 1300-0322 |
| Relation: | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı; Türkiye Klinikleri Gastroenterohepatoloji Dergisi; https://hdl.handle.net/11454/14950; https://app.trdizin.gov.tr/makale/TWpNd016TXo; 14; 70; 75 |
| الاتاحة: | https://hdl.handle.net/11454/14950 https://app.trdizin.gov.tr/makale/TWpNd016TXo |
| Rights: | open |
| رقم الانضمام: | edsbas.270DC0B4 |
| قاعدة البيانات: | BASE |
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