Academic Journal
Protein fractionation of pH‐responsive brush‐modified ethylene vinyl alcohol copolymer membranes*
| العنوان: | Protein fractionation of pH‐responsive brush‐modified ethylene vinyl alcohol copolymer membranes* |
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| المؤلفون: | Ye, Hui, Zhou, Yining, Yang, Guodong, Yu, Tengfei, Zhang, Yuzhong, Zhao, Lizhi, Xin, Qingping, Han, Shurui |
| المساهمون: | Natural Science Foundation of Tianjin Municipal Science and Technology Commission, National Natural Science Foundation of China |
| المصدر: | Polymer Engineering & Science ; volume 62, issue 4, page 1041-1051 ; ISSN 0032-3888 1548-2634 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2022 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Protein fractionation and purification remain challenging in membrane separation. Herein, a pH‐responsive membrane was developed by grafting the brush‐like poly(dimethylaminoethyl methacrylate) (PDMAEMA) via ATRP onto the ethylene vinyl alcohol copolymer (EVAL) membrane for protein fractionation. The PDMAEMA brushes are distributed in all pore channels of the membrane. Based on the electrostatic and sieving properties of the as‐prepared pH‐responsive membrane, three milk proteins are successfully separated from their mixture. The α‐Lactalbumin (α‐LA) preferentially permeates the membrane from the mixture at pH 3.2, and the bovine serum albumin (BSA) and lactoferrin (LF) can be separated at pH 6.4 based on the selective adsorption. This work proposes a promising candidate for protein separation by a pH‐responsive membrane. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/pen.25904 |
| الاتاحة: | http://dx.doi.org/10.1002/pen.25904 https://onlinelibrary.wiley.com/doi/pdf/10.1002/pen.25904 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/pen.25904 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.249C6C5D |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/pen.25904 |
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