Dissertation/ Thesis
Numerical simulation of fluid-structure interactions in a stenotic arteriovenous fistula and the effects of endovascular treatments ; Simulation numérique des interactions fluide-structure dans une fistule artério-veineuse sténosée et des effets de traitements endovasculaires
| العنوان: | Numerical simulation of fluid-structure interactions in a stenotic arteriovenous fistula and the effects of endovascular treatments ; Simulation numérique des interactions fluide-structure dans une fistule artério-veineuse sténosée et des effets de traitements endovasculaires |
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| المؤلفون: | Decorato, Iolanda |
| المساهمون: | Biomécanique et Bioingénierie (BMBI), Université de Technologie de Compiègne (UTC)-Centre National de la Recherche Scientifique (CNRS), Université de Technologie de Compiègne, Anne-Virginie Salsac, Zaher Kharboutly |
| المصدر: | https://theses.hal.science/tel-00832342 ; Médecine humaine et pathologie. Université de Technologie de Compiègne, 2013. Français. ⟨NNT : 2013COMP2061⟩. |
| بيانات النشر: | HAL CCSD |
| سنة النشر: | 2013 |
| المجموعة: | Université de Technologie de Compiègne: HAL |
| مصطلحات موضوعية: | Arteriovenous fistula, Wall compliance, Fluid-structure interaction simulation, Arterial stenosis, Balloon-angioplasty, Stent positioning, Simulation numérique, Traitements endovasculaires, Compliance vasculaire, Sténose artérielle, Angioplastie par ballonnet, Positionnement d'un stent, FAV, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| الوصف: | An arteriovenous fistula (AVF) is a permanent vascular access created surgically connecting a vein onto an artery. It enables to circulate blood extra-corporeally in order to clean it from metabolic waste products and excess of water for patients with end-stage renal disease undergoing hemodialysis. The hemodynamics results to be significantly altered within the arteriovenous fistula compared to the physiological situation. Several studies have been carried out in order to better understand the consequences of AVF creation, maturation and frequent use, but many clinical questions still lie unanswered. The aim of the present study is to better understand the hemodynamics within the AVF, when the compliance of the vascularwall is taken into account. We also propose to quantify the effect of a stenosis at the afferent artery, the incidence of which has been underestimated for many years. The fluid-structure interactions (FSI) within a patient-specific radio-cephalic arteriovenous fistula are investigated numerically. The considered AVF presents an 80% stenosis at the afferent artery. The patient-specific velocity profile is imposed at the boundary inlet, and a Windkessel model is set at the arterial and venous outlets. The mechanical properties of the vein and the artery are differentiated. The non-Newtonian blood behavior has been taken into account. The FSI simulation advantageously provides the time-evolution of both the hemodynamic and structural stresses, and guarantees the equilibrium of the solution at the interface between the fluid and solid domains. The FSI results show the presence of large zones of blood flow recirculation within the cephalic vein, which might promote neointima formation. Large internal stresses are also observed at the venous wall, which may lead to wall remodeling. The fully-coupled FSI simulation results to be costly in computational time, which can so far limit its clinical use. We have investigated whether uncoupled fluid and structure simulations can provide accurate results and ... |
| نوع الوثيقة: | doctoral or postdoctoral thesis |
| اللغة: | French |
| Relation: | NNT: 2013COMP2061 |
| الاتاحة: | https://theses.hal.science/tel-00832342 https://theses.hal.science/tel-00832342v1/document https://theses.hal.science/tel-00832342v1/file/These_UTC_Iolanda_Decorato.pdf |
| Rights: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.1CC6AF39 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |