Academic Journal
أعرض في EDS

Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials

التفاصيل البيبلوغرافية
العنوان: Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials
المؤلفون: Leis Trabazo, María Rosaura, De Castro López, María José, de Lamas, C., Picans Leis, Rosaura, Couce Pico, María Luz
سنة النشر: 2020
مصطلحات موضوعية: Diarrhea, Humans, Flatulence, Lactase, Diet, Animals, Milk, Lactose Intolerance, Vomiting, Abdominal Pain, Lactose, dolor abdominal, animales, lactosa, diarrea, vómitos, humanos, flatulencia, leche, lactasa, dieta, intolerancia a la lactosa, CHUS, IDIS
الوصف: Lactose intolerance (LI) is characterized by the presence of primarily gastrointestinal clinical signs resulting from colonic fermentation of lactose, the absorption of which is impaired due to a deficiency in the lactase enzyme. These clinical signs can be modified by several factors, including lactose dose, residual lactase expression, concurrent ingestion of other dietary components, gut-transit time, and enteric microbiome composition. In many of individuals with lactose malabsorption, clinical signs may be absent after consumption of normal amounts of milk or, in particular, dairy products (yogurt and cheese), which contain lactose partially digested by live bacteria. The intestinal microbiota can be modulated by biotic supplementation, which may alleviate the signs and symptoms of LI. This systematic review summarizes the available evidence on the influence of prebiotics and probiotics on lactase deficiency and LI. The literature search was conducted using the MEDLINE (via PUBMED) and SCOPUS databases following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and included randomized controlled trials. For each study selected, the risk of bias was assessed following the Cochrane Collaboration methodology. Our findings showed varying degrees of efficacy but an overall positive relationship between probiotics and LI in relation to specific strains and concentrations. Limitations regarding the wide heterogeneity between the studies included in this review should be taken into account. Only one study examined the benefits of prebiotic supplementation and LI. So further clinical trials are needed in order to gather more evidence.
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
تدمد: 2072-6643
Relation: https://www.ncbi.nlm.nih.gov/pubmed/32443748; http://hdl.handle.net/20.500.11940/16527; 39169
DOI: 10.3390/nu12051487
الاتاحة: https://hdl.handle.net/20.500.11940/16527
https://www.ncbi.nlm.nih.gov/pubmed/32443748
https://doi.org/10.3390/nu12051487
Rights: Atribución 4.0 Internacional ; http://creativecommons.org/licenses/by/4.0/ ; openAccess
رقم الانضمام: edsbas.19F96365
قاعدة البيانات: BASE
ResultId 1
Header edsbas
BASE
edsbas.19F96365
905
3
Academic Journal
academicJournal
905.017944335938
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsbas&AN=edsbas.19F96365&custid=s6537998&authtype=sso
FullText Array ( [Availability] => 0 )
Array ( [0] => Array ( [Url] => https://hdl.handle.net/20.500.11940/16527# [Name] => EDS - BASE [Category] => fullText [Text] => View record in BASE [MouseOverText] => View record in BASE ) [1] => Array ( [Url] => https://resolver.ebscohost.com/openurl?custid=s6537998&groupid=main&authtype=ip,guest&sid=EBSCO:edsbas&genre=article&issn=20726643&ISBN=&volume=&issue=&date=20200101&spage=&pages=&title=Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials&atitle=Effects%20of%20Prebiotic%20and%20Probiotic%20Supplementation%20on%20Lactase%20Deficiency%20and%20Lactose%20Intolerance%3A%20A%20Systematic%20Review%20of%20Controlled%20Trials&id=DOI:10.3390/nu12051487 [Name] => Full Text Finder (s6537998api) [Category] => fullText [Text] => Full Text Finder [Icon] => https://imageserver.ebscohost.com/branding/images/FTF.gif [MouseOverText] => Full Text Finder ) )
Items Array ( [Name] => Title [Label] => Title [Group] => Ti [Data] => Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials )
Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => <searchLink fieldCode="AR" term="%22Leis+Trabazo%2C+María+Rosaura%22">Leis Trabazo, María Rosaura</searchLink><br /><searchLink fieldCode="AR" term="%22De+Castro+López%2C+María+José%22">De Castro López, María José</searchLink><br /><searchLink fieldCode="AR" term="%22de+Lamas%2C+C%2E%22">de Lamas, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Picans+Leis%2C+Rosaura%22">Picans Leis, Rosaura</searchLink><br /><searchLink fieldCode="AR" term="%22Couce+Pico%2C+María+Luz%22">Couce Pico, María Luz</searchLink> )
Array ( [Name] => DatePubCY [Label] => Publication Year [Group] => Date [Data] => 2020 )
Array ( [Name] => Subject [Label] => Subject Terms [Group] => Su [Data] => <searchLink fieldCode="DE" term="%22Diarrhea%22">Diarrhea</searchLink><br /><searchLink fieldCode="DE" term="%22Humans%22">Humans</searchLink><br /><searchLink fieldCode="DE" term="%22Flatulence%22">Flatulence</searchLink><br /><searchLink fieldCode="DE" term="%22Lactase%22">Lactase</searchLink><br /><searchLink fieldCode="DE" term="%22Diet%22">Diet</searchLink><br /><searchLink fieldCode="DE" term="%22Animals%22">Animals</searchLink><br /><searchLink fieldCode="DE" term="%22Milk%22">Milk</searchLink><br /><searchLink fieldCode="DE" term="%22Lactose+Intolerance%22">Lactose Intolerance</searchLink><br /><searchLink fieldCode="DE" term="%22Vomiting%22">Vomiting</searchLink><br /><searchLink fieldCode="DE" term="%22Abdominal+Pain%22">Abdominal Pain</searchLink><br /><searchLink fieldCode="DE" term="%22Lactose%22">Lactose</searchLink><br /><searchLink fieldCode="DE" term="%22dolor+abdominal%22">dolor abdominal</searchLink><br /><searchLink fieldCode="DE" term="%22animales%22">animales</searchLink><br /><searchLink fieldCode="DE" term="%22lactosa%22">lactosa</searchLink><br /><searchLink fieldCode="DE" term="%22diarrea%22">diarrea</searchLink><br /><searchLink fieldCode="DE" term="%22vómitos%22">vómitos</searchLink><br /><searchLink fieldCode="DE" term="%22humanos%22">humanos</searchLink><br /><searchLink fieldCode="DE" term="%22flatulencia%22">flatulencia</searchLink><br /><searchLink fieldCode="DE" term="%22leche%22">leche</searchLink><br /><searchLink fieldCode="DE" term="%22lactasa%22">lactasa</searchLink><br /><searchLink fieldCode="DE" term="%22dieta%22">dieta</searchLink><br /><searchLink fieldCode="DE" term="%22intolerancia+a+la+lactosa%22">intolerancia a la lactosa</searchLink><br /><searchLink fieldCode="DE" term="%22CHUS%22">CHUS</searchLink><br /><searchLink fieldCode="DE" term="%22IDIS%22">IDIS</searchLink> )
Array ( [Name] => Abstract [Label] => Description [Group] => Ab [Data] => Lactose intolerance (LI) is characterized by the presence of primarily gastrointestinal clinical signs resulting from colonic fermentation of lactose, the absorption of which is impaired due to a deficiency in the lactase enzyme. These clinical signs can be modified by several factors, including lactose dose, residual lactase expression, concurrent ingestion of other dietary components, gut-transit time, and enteric microbiome composition. In many of individuals with lactose malabsorption, clinical signs may be absent after consumption of normal amounts of milk or, in particular, dairy products (yogurt and cheese), which contain lactose partially digested by live bacteria. The intestinal microbiota can be modulated by biotic supplementation, which may alleviate the signs and symptoms of LI. This systematic review summarizes the available evidence on the influence of prebiotics and probiotics on lactase deficiency and LI. The literature search was conducted using the MEDLINE (via PUBMED) and SCOPUS databases following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and included randomized controlled trials. For each study selected, the risk of bias was assessed following the Cochrane Collaboration methodology. Our findings showed varying degrees of efficacy but an overall positive relationship between probiotics and LI in relation to specific strains and concentrations. Limitations regarding the wide heterogeneity between the studies included in this review should be taken into account. Only one study examined the benefits of prebiotic supplementation and LI. So further clinical trials are needed in order to gather more evidence. )
Array ( [Name] => TypeDocument [Label] => Document Type [Group] => TypDoc [Data] => article in journal/newspaper )
Array ( [Name] => Language [Label] => Language [Group] => Lang [Data] => unknown )
Array ( [Name] => ISSN [Label] => ISSN [Group] => ISSN [Data] => 2072-6643 )
Array ( [Name] => NoteTitleSource [Label] => Relation [Group] => SrcInfo [Data] => https://www.ncbi.nlm.nih.gov/pubmed/32443748; http://hdl.handle.net/20.500.11940/16527; 39169 )
Array ( [Name] => DOI [Label] => DOI [Group] => ID [Data] => 10.3390/nu12051487 )
Array ( [Name] => URL [Label] => Availability [Group] => URL [Data] => https://hdl.handle.net/20.500.11940/16527<br />https://www.ncbi.nlm.nih.gov/pubmed/32443748<br />https://doi.org/10.3390/nu12051487 )
Array ( [Name] => Copyright [Label] => Rights [Group] => Cpyrght [Data] => Atribución 4.0 Internacional ; http://creativecommons.org/licenses/by/4.0/ ; openAccess )
Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsbas.19F96365 )
RecordInfo Array ( [BibEntity] => Array ( [Identifiers] => Array ( [0] => Array ( [Type] => doi [Value] => 10.3390/nu12051487 ) ) [Languages] => Array ( [0] => Array ( [Text] => unknown ) ) [Subjects] => Array ( [0] => Array ( [SubjectFull] => Diarrhea [Type] => general ) [1] => Array ( [SubjectFull] => Humans [Type] => general ) [2] => Array ( [SubjectFull] => Flatulence [Type] => general ) [3] => Array ( [SubjectFull] => Lactase [Type] => general ) [4] => Array ( [SubjectFull] => Diet [Type] => general ) [5] => Array ( [SubjectFull] => Animals [Type] => general ) [6] => Array ( [SubjectFull] => Milk [Type] => general ) [7] => Array ( [SubjectFull] => Lactose Intolerance [Type] => general ) [8] => Array ( [SubjectFull] => Vomiting [Type] => general ) [9] => Array ( [SubjectFull] => Abdominal Pain [Type] => general ) [10] => Array ( [SubjectFull] => Lactose [Type] => general ) [11] => Array ( [SubjectFull] => dolor abdominal [Type] => general ) [12] => Array ( [SubjectFull] => animales [Type] => general ) [13] => Array ( [SubjectFull] => lactosa [Type] => general ) [14] => Array ( [SubjectFull] => diarrea [Type] => general ) [15] => Array ( [SubjectFull] => vómitos [Type] => general ) [16] => Array ( [SubjectFull] => humanos [Type] => general ) [17] => Array ( [SubjectFull] => flatulencia [Type] => general ) [18] => Array ( [SubjectFull] => leche [Type] => general ) [19] => Array ( [SubjectFull] => lactasa [Type] => general ) [20] => Array ( [SubjectFull] => dieta [Type] => general ) [21] => Array ( [SubjectFull] => intolerancia a la lactosa [Type] => general ) [22] => Array ( [SubjectFull] => CHUS [Type] => general ) [23] => Array ( [SubjectFull] => IDIS [Type] => general ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials [Type] => main ) ) ) [BibRelationships] => Array ( [HasContributorRelationships] => Array ( [0] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Leis Trabazo, María Rosaura ) ) ) [1] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => De Castro López, María José ) ) ) [2] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => de Lamas, C. ) ) ) [3] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Picans Leis, Rosaura ) ) ) [4] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Couce Pico, María Luz ) ) ) ) [IsPartOfRelationships] => Array ( [0] => Array ( [BibEntity] => Array ( [Dates] => Array ( [0] => Array ( [D] => 01 [M] => 01 [Type] => published [Y] => 2020 ) ) [Identifiers] => Array ( [0] => Array ( [Type] => issn-print [Value] => 20726643 ) [1] => Array ( [Type] => issn-locals [Value] => edsbas ) [2] => Array ( [Type] => issn-locals [Value] => edsbas.oa ) ) ) ) ) ) )
IllustrationInfo