Academic Journal
Systematic coformer contribution to cocrystal stabilization : energy and packing trends
| العنوان: | Systematic coformer contribution to cocrystal stabilization : energy and packing trends |
|---|---|
| المؤلفون: | Mazzeo, Paolo P., Canossa, Stefano, Carraro, Claudia, Pelagatti, Paolo, Bacchi, Alessia |
| المصدر: | 1466-8033 ; CrystEngComm |
| سنة النشر: | 2020 |
| المجموعة: | IRUA - Institutional Repository van de Universiteit Antwerpen |
| مصطلحات موضوعية: | Chemistry |
| الوصف: | Polycyclic aromatic compounds such as acridine and phenazine are popular molecular partners used in cocrystal synthesis. The intermolecular interactions occurring between coformers and their molecular partners dominate the cocrystal packing energy, but coformer self-interactions might participate with a constant non-negligible contribution to the overall packing energy stabilization. Two new acridine-based cocrystals have been mechanochemically synthesized, then fully characterized via DSC and SCXRD analyses. A statistical analysis in the CSD has been performed to evaluate the recurrent pi-pi stacking orientation of polycyclic coformers in all deposited acridine-based cocrystals, then extended to phenazine-base analogs. Packing energy calculations were performed on a selected cocrystal subset to quantify the contribution of the pi-pi interaction to the overall stabilization energy. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/isi/000589506600017 |
| الاتاحة: | https://hdl.handle.net/10067/1742620151162165141 https://repository.uantwerpen.be/docstore/d:irua:4270 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.15E16B3E |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |