التفاصيل البيبلوغرافية
| العنوان: |
G protein-activated K+ channels: a reporter for rapid activation of G proteins by lysophosphatidic acid in Xenopus oocytes |
| المؤلفون: |
Irit Itzhaki Van-Ham, Yoram Oron, Nathan Dascal, Sagit Peleg, Hagit Shapira |
| المصدر: |
FEBS Letters. (1-2):157-160 |
| بيانات النشر: |
Published by Elsevier B.V. |
| مصطلحات موضوعية: |
Potassium Channels, Microinjections, G protein, Xenopus, Go/i protein, Biophysics, Rodentia, Rapid desensitization, Biology, GTP-Binding Protein alpha Subunits, Gi-Go, Pertussis toxin, Biochemistry, Membrane Potentials, chemistry.chemical_compound, G protein-activated potassium channel, Structural Biology, GTP-Binding Proteins, Lysophosphatidic acid, Genetics, medicine, Animals, G protein-coupled inwardly-rectifying potassium channel, RNA, Messenger, Potassium Channels, Inwardly Rectifying, Molecular Biology, K channels, Cell Biology, biology.organism_classification, Molecular biology, Electrophysiology, chemistry, G Protein-Coupled Inwardly-Rectifying Potassium Channels, Oocytes, Potassium, lipids (amino acids, peptides, and proteins), Lysophosphatidic acid receptor, Lysophospholipids, biological phenomena, cell phenomena, and immunity, Acetylcholine, medicine.drug |
| الوصف: |
Threshold concentrations of lysophosphatidic acid (LPA) or acetylcholine (ACh) induce pertussis toxin (PTX)-sensitive rapid desensitization of responses to LPA in Xenopus oocytes. To demonstrate that threshold [LPA] rapidly activates Gi/o proteins, we used the G protein-activated K+ channel (GIRK) as a reporter. Low [LPA] induced IK+ in |
| اللغة: |
English |
| تدمد: |
0014-5793 |
| DOI: |
10.1016/S0014-5793(04)00334-5 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc3839a289116842b11b336b778a2be1 |
| Rights: |
OPEN |
| رقم الانضمام: |
edsair.doi.dedup.....fc3839a289116842b11b336b778a2be1 |
| قاعدة البيانات: |
OpenAIRE |