Single-bacterium nanomechanics in biomedicine: unravelling the dynamics of bacterial cells
| العنوان: | Single-bacterium nanomechanics in biomedicine: unravelling the dynamics of bacterial cells |
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| المؤلفون: | Laurent Bozec, Dave Spratt, Nikolaos Donos, Sebastian Aguayo |
| المصدر: | Nanotechnology. 26:062001 |
| بيانات النشر: | IOP Publishing, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Materials science, Surface Properties, Biomedical Technology, Bioengineering, Nanotechnology, Bacterial Physiological Phenomena, Microscopy, Atomic Force, Bacterial Adhesion, Biomechanical Phenomena, Animals, Humans, General Materials Science, Electrical and Electronic Engineering, Biomedicine, business.industry, Mechanical Engineering, Biofilm, Force spectroscopy, General Chemistry, Adhesion, Nanoindentation, Mechanics of Materials, Biofilms, Biophysics, Nanoparticles, business, Nanomechanics |
| الوصف: | The use of the atomic force microscope (AFM) in microbiology has progressed significantly throughout the years since its first application as a high-resolution imaging instrument. Modern AFM setups are capable of characterizing the nanomechanical behaviour of bacterial cells at both the cellular and molecular levels, where elastic properties and adhesion forces of single bacterium cells can be examined under different experimental conditions. Considering that bacterial and biofilm-mediated infections continue to challenge the biomedical field, it is important to understand the biophysical events leading towards bacterial adhesion and colonization on both biological and non-biological substrates. The purpose of this review is to present the latest findings concerning the field of single-bacterium nanomechanics, and discuss future trends and applications of nanoindentation and single-cell force spectroscopy techniques in biomedicine. |
| تدمد: | 1361-6528 0957-4484 |
| DOI: | 10.1088/0957-4484/26/6/062001 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f787fb2be6d68a4ae83ff25d7b25829b https://doi.org/10.1088/0957-4484/26/6/062001 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f787fb2be6d68a4ae83ff25d7b25829b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13616528 09574484 |
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| DOI: | 10.1088/0957-4484/26/6/062001 |