Delayed Presentation of Isolated Adrenocorticotropin Insufficiency after Nivolumab Therapy for Advanced Non-small-cell lung carcinoma (NSCLC)

التفاصيل البيبلوغرافية
العنوان: Delayed Presentation of Isolated Adrenocorticotropin Insufficiency after Nivolumab Therapy for Advanced Non-small-cell lung carcinoma (NSCLC)
المؤلفون: Erin Sarzynski, Shiva Shrotriya, Ahmad Alratroot, Manoj P Rai
المصدر: BMJ Case Rep
سنة النشر: 2018
مصطلحات موضوعية: Male, medicine.medical_specialty, Lung Neoplasms, Side effect, 030209 endocrinology & metabolism, Antineoplastic Agents, Gastroenterology, Malaise, Diagnosis, Differential, 03 medical and health sciences, 0302 clinical medicine, Addison Disease, Adrenocorticotropic Hormone, Weight loss, Internal medicine, Carcinoma, Non-Small-Cell Lung, Carcinoma, medicine, Adrenal insufficiency, Humans, Aged, Lung, Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions, business.industry, Antibodies, Monoclonal, General Medicine, medicine.disease, medicine.anatomical_structure, Nivolumab, 030220 oncology & carcinogenesis, Etiology, medicine.symptom, business
الوصف: We describe a 73-year-old man who developed adrenal insufficiency 7 months after completing nivolumab therapy for advanced non-small cell lung cancer. He presented with non-specific symptoms of malaise and fatigue with an insidious 13.6 kilogram weight loss, prompting an evaluation for disease progression, which was negative. Subsequent evaluation revealed isolated adrenocorticotropin insufficiency as the aetiology, attributed to a delayed side effect of nivolumab therapy.
تدمد: 1757-790X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f479b4f2e283b9cd5a3f46e4d50d5ab7
https://pubmed.ncbi.nlm.nih.gov/30093497
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....f479b4f2e283b9cd5a3f46e4d50d5ab7
قاعدة البيانات: OpenAIRE