CD4+ T-cell responses to self-peptide--MHC
| العنوان: | CD4+ T-cell responses to self-peptide--MHC |
|---|---|
| المؤلفون: | Ailin Bai, Herman N. Eisen, Ching-Hung Shen, Jianzhu Chen, Qing Ge |
| المصدر: | Trends in immunology. 24(4) |
| سنة النشر: | 2003 |
| مصطلحات موضوعية: | CD4-Positive T-Lymphocytes, Mice, Knockout, MHC class II, biology, Cd4 t cell, Cell Survival, Immunology, T-cell receptor, Histocompatibility Antigens Class II, chemical and pharmacologic phenomena, Autoimmunity, Autoantigens, Mice, biology.protein, Immunology and Allergy, Peptide-MHC, Animals, Humans, Receptor, Cell Division, Gene Deletion |
| الوصف: | Interactions between the T-cell receptor (TCR) and self-peptide–MHC (spMHC) have been hypothesized to modulate T-cell reactivity in the periphery. Recent studies examining CD4 + T-cell responses to spMHC class II describe apparently contradictory findings and arrive at opposite conclusions. One explanation for these seemingly disparate results could be the use of mice that were assumed to be MHC class II null but might express some uncommon MHC class II heterodimers. |
| تدمد: | 1471-4906 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e779f5b708e2f09f717300de639c7e8d https://pubmed.ncbi.nlm.nih.gov/12967668 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....e779f5b708e2f09f717300de639c7e8d |
| قاعدة البيانات: | OpenAIRE |
كن أول من يترك تعليقا!