Sex-Related Differences in Patients With Inflammatory Bowel Disease: Results of 2 Prospective Cohort Studies
| العنوان: | Sex-Related Differences in Patients With Inflammatory Bowel Disease: Results of 2 Prospective Cohort Studies |
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| المؤلفون: | Frank Hoentjen, Cyriel Y. Ponsioen, Cees H. M. Clemens, Paul C. van de Meeberg, Andrea E. van der Meulen-de Jong, Mirjam Severs, Janneke van der Woude, Bas Oldenburg, Eleonora A. M. Festen, Lieke M. Spekhorst, Mark Löwenberg, Bindia Jharap, Gerard Dijkstra, Herma H. Fidder, Nofel Mahmmod, Jeroen M. Jansen, Rinse K. Weersma, Mariëlle Romberg-Camps, Marie-Josée J. Mangen, Marieke Pierik, Gerd Bouma, Mirthe E. van der Valk |
| المساهمون: | Gastroenterology and hepatology, AGEM - Digestive immunity, AGEM - Re-generation and cancer of the digestive system, AII - Inflammatory diseases, Gastroenterology & Hepatology, Interne Geneeskunde, MUMC+: MA Maag Darm Lever (9), RS: NUTRIM - R2 - Liver and digestive health, Gastroenterology and Hepatology, AGEM - Endocrinology, metabolism and nutrition, Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Translational Immunology Groningen (TRIGR), Groningen Institute for Organ Transplantation (GIOT) |
| المصدر: | Inflammatory Bowel Diseases Inflammatory Bowel Diseases, 24(6), 1298-1306. John Wiley and Sons Inc. Inflammatory Bowel Diseases, 24(6), 1298-1306 Inflammatory Bowel Diseases, 24, 1298-1306 Inflammatory Bowel Diseases, 24(6), 1298-1306. Oxford University Press Inflammatory Bowel Diseases, 24, 6, pp. 1298-1306 Inflammatory Bowel Diseases, 24(6), 1298-1306. LIPPINCOTT WILLIAMS & WILKINS Severs, M, Spekhorst, L M, Mangen, M-J J, Dijkstra, G, Löwenberg, M, Hoentjen, F, van der Meulen-de Jong, A E, Pierik, M, Ponsioen, C Y, Bouma, G, van der Woude, J C, van der Valk, M E, Romberg-Camps, M J L, Clemens, C H M, van de Meeberg, P, Mahmmod, N, Jansen, J, Jharap, B, Weersma, R K, Oldenburg, B, Festen, E A M & Fidder, H H 2018, ' Sex-Related Differences in Patients with Inflammatory Bowel Disease: Results of 2 Prospective Cohort Studies ', Inflammatory Bowel Diseases, vol. 24, no. 6, pp. 1298-1306 . https://doi.org/10.1093/ibd/izy004 Inflammatory bowel diseases, 24(6), 1298-1306. John Wiley and Sons Inc. |
| بيانات النشر: | LIPPINCOTT WILLIAMS & WILKINS, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, EXTRAINTESTINAL MANIFESTATIONS, CLINICAL-COURSE, Disease, Severity of Illness Index, Inflammatory bowel disease, 0302 clinical medicine, Crohn Disease, Risk Factors, PRECISION MEDICINE, Prevalence, gender, Immunology and Allergy, Medicine, Prospective Studies, Prospective cohort study, Netherlands, Crohn's disease, Gastroenterology, Middle Aged, Ulcerative colitis, CROHNS-DISEASE, ULCERATIVE-COLITIS, Cohort, Female, 030211 gastroenterology & hepatology, Inflammatory diseases Radboud Institute for Molecular Life Sciences [Radboudumc 5], Cohort study, Adult, medicine.medical_specialty, 03 medical and health sciences, Sex Factors, All institutes and research themes of the Radboud University Medical Center, inflammatory bowel disease, Internal medicine, Humans, sex, ulcerative colitis, GENDER-DIFFERENCES, PEDIATRIC-PATIENTS, business.industry, medicine.disease, digestive system diseases, RHEUMATOID-ARTHRITIS, POSTOPERATIVE RECURRENCE, 030104 developmental biology, RISK-FACTORS, Colitis, Ulcerative, Age of onset, business |
| الوصف: | Background: The understanding of gender differences in inflammatory bowel disease (IBD) patients is an important step towards tailored treatment for the individual patient. The aim of this study was to compare disease phenotype, clinical manifestations, disease activity, and healthcare utilization between men and women with Crohn's disease (CD) and ulcerative colitis (UC).Methods: Two multicenter observational cohort studies with a prospective design were used to explore the differences between men and women regarding demographic and phenotypic characteristics and healthcare utilization. Detailed data on IBD-phenotype was mainly available from the Dutch IBD Biobank, while the COIN cohort provided healthcare utilization data.Results: In the Dutch IBD Biobank study, 2118 CD patients and 1269 UC patients were analyzed. Female CD patients were more often current smokers, and male UC patients were more often previous smokers. Early onset CD (Conclusions: Sex differences in patients with IBD include age of onset, disease location, and EIM prevalence. No large differences in therapeutic management of IBD were observed between men and women with IBD. |
| اللغة: | English |
| تدمد: | 1536-4844 1078-0998 |
| DOI: | 10.1093/ibd/izy004 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5caa96e06cc3b1ea30f4b46267a51b0 https://doi.org/10.1093/ibd/izy004 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e5caa96e06cc3b1ea30f4b46267a51b0 |
| قاعدة البيانات: | OpenAIRE |
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