Effect of dietary vitamin B6contents on antibody production
| العنوان: | Effect of dietary vitamin B6contents on antibody production |
|---|---|
| المؤلفون: | A. Matsui, E. Murata, Nobuhiko Katunuma, Tomoko Inubushi, M. Okada, J. Hanba |
| المصدر: | BioFactors. 11:93-96 |
| بيانات النشر: | Wiley, 2000. |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | medicine.medical_specialty, Clinical Biochemistry, Immunoglobulin E, Biochemistry, Dietary vitamin, Cathepsin B, Mice, Internal medicine, Casein, medicine, Animals, biology, Chemistry, Pyridoxine, General Medicine, Diet, Antibody production, Endocrinology, Liver, Antibody Formation, biology.protein, Molecular Medicine, Antibody, Vitamin b6, Vitamin B 6 Deficiency, medicine.drug |
| الوصف: | When mice were placed on diets extreme deficient in vitamin B6, ovalbumin-dependent antibody productions (IgE, IgG1, IgG2a) were significantly suppressed, and alanine aminotransferase activity in the liver was also significantly decreased. In the case of pyridoxine excess (6 mg% = about ten times standard amount) in a 70% casein diet, ovalbumin-dependent antibody productions were also considerably suppressed. These responses were weaker in a low casein (5%) or normal casein (20%) diet than in a 70% casein diet. The administration of high doses of pyridoxine (6 mg%) resulted in the suppression of hepatic cathepsin B activity. Therefore, we conclude that ovalbumin-dependent antibody productions (IgG1, IgE) were suppressed by pyridoxine excess diet (6 mg%), because hepatic cathepsin B activity was suppressed by the excess pyridoxine in diet. |
| تدمد: | 1872-8081 0951-6433 |
| DOI: | 10.1002/biof.5520110127 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decaef9415b20c25146c98e4937b8d00 https://doi.org/10.1002/biof.5520110127 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....decaef9415b20c25146c98e4937b8d00 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18728081 09516433 |
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| DOI: | 10.1002/biof.5520110127 |