Hepatocellular carcinoma in older adults: A comprehensive review by Young International Society of Geriatric Oncology

التفاصيل البيبلوغرافية
العنوان: Hepatocellular carcinoma in older adults: A comprehensive review by Young International Society of Geriatric Oncology
المؤلفون: Efrat Dotan, Richard F. Dunne, Gabor Liposits, Susan Caird, Sukeshi Patel Arora, David Okonji, Gordon T Moffat, Maria Grazia Rodriquenz, Divyanshu Dua
المصدر: J Geriatr Oncol
سنة النشر: 2019
مصطلحات موضوعية: medicine.medical_specialty, Carcinoma, Hepatocellular, Population, Article, 03 medical and health sciences, 0302 clinical medicine, Older patients, medicine, Humans, 030212 general & internal medicine, Intensive care medicine, education, Aged, education.field_of_study, business.industry, Incidence (epidemiology), Liver Neoplasms, medicine.disease, digestive system diseases, Clinical trial, Patient population, Oncology, Geriatric oncology, Treatment modality, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Geriatrics and Gerontology, business
الوصف: Given the prevalence and the rising incidence of hepatocellular carcinoma (HCC) in older adults worldwide, there is an urgent need to improve our understanding of the implications of treatment modalities in this population. The care of older patients with HCC is challenging due to the lack of evidence-based recommendations in this population. The current treatment approach for older patients relies on extrapolation of data from clinical trials conducted mostly in younger patients or fit older adults. Further, in the last few years, the arsenal of systemic treatments has increased with currently seven FDA-approved therapies available for patients with advanced HCC. Therefore, understanding how to apply current data to this unique and diverse patient population is necessary. This review will aim to shed light on the approach to older adults with HCC through an assessment of available data in the literature.
اللغة: English
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8edd481992887f4436e8deab8abf07
https://europepmc.org/articles/PMC7188597/
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....de8edd481992887f4436e8deab8abf07
قاعدة البيانات: OpenAIRE
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