Bioorthogonal ligation in the spotlight
| العنوان: | Bioorthogonal ligation in the spotlight |
|---|---|
| المؤلفون: | Henning D. Mootz, Thomas Kurpiers |
| المصدر: | Angewandte Chemie (International ed. in English). 48(10) |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Time Factors, Alkene, Ultraviolet Rays, Proteins, Tetrazoles, Pyrazoline, General Chemistry, Alkenes, Photochemistry, Photochemical Processes, Combinatorial chemistry, Catalysis, Cycloaddition, Adduct, chemistry.chemical_compound, chemistry, Covalent bond, Cyclization, Moiety, Tetrazole, Bioorthogonal chemistry, Fluorescent Dyes |
| الوصف: | The light-induced formation of a covalent bond between an alkene group and a tetrazole moiety has been used for the selective labeling of proteins in vitro and in live cells. This bioorthogonal ligation initiated by brief irradiation with UV light leads to a fluorescent pyrazoline adduct (see scheme). |
| تدمد: | 1521-3773 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd031eeafe831b9057f43c79ded038f9 https://pubmed.ncbi.nlm.nih.gov/18311742 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....bd031eeafe831b9057f43c79ded038f9 |
| قاعدة البيانات: | OpenAIRE |
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