أعرض في EDS

An Unusual Association of Adult T-Cell Leukemia/Lymphoma With Hyalohyphomycosis

التفاصيل البيبلوغرافية
العنوان: An Unusual Association of Adult T-Cell Leukemia/Lymphoma With Hyalohyphomycosis
المؤلفون: Herbert Henrique de Melo Santos, Pedro D. Oliveira, Marco Aurelio Salvino, Achiléa L. Bittencourt
المصدر: The American Journal of Dermatopathology. 38:370-373
بيانات النشر: Ovid Technologies (Wolters Kluwer Health), 2016.
سنة النشر: 2016
مصطلحات موضوعية: Adult, Hyalohyphomycosis, Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Antifungal Agents, Lymphocytosis, Biopsy, medicine.medical_treatment, 030106 microbiology, Antineoplastic Agents, Dermatology, Adult T-cell leukemia/lymphoma, Pathology and Forensic Medicine, Immunocompromised Host, 03 medical and health sciences, Fatal Outcome, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, medicine, Dermatomycoses, Humans, Leukemia-Lymphoma, Adult T-Cell, Lymph node, Human T-lymphotropic virus 1, Chemotherapy, biology, business.industry, General Medicine, medicine.disease, biology.organism_classification, HTLV-I Infections, Lymphoma, Leukemia, Treatment Outcome, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Disease Progression, medicine.symptom, business
الوصف: Infection by human T-cell lymphotropic virus (HTLV-1) causes deregulation of the immune system, which makes the infected individuals more susceptible to infectious diseases. Immune deregulation is even more pronounced in HTLV-1 carriers with adult T-cell leukemia/lymphoma (ATLL), which results in frequent opportunistic infections. Hyalohyphomycosis is a rare subcutaneous mycosis which is more commonly associated with immunocompromised patients. We report a case of a HTLV-1-infected man with skin tumors, inguinal lymphadenomegaly, and lymphocytosis. Histopathological examination of skin biopsies revealed a T-cell lymphoma intermingled with a granulomatous process with abscesses and hyaline-septated hyphae. The lymph node showed only a T-cell lymphoma. The patient was diagnosed with acute ATLL and hyalohyphomycosis. He was treated with itraconazole for the subcutaneous mycosis and with chemotherapy for ATLL. A few months later, despite the treatment, he died because of progression of ATLL.
تدمد: 0193-1091
DOI: 10.1097/dad.0000000000000533
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c1f9b7eadbfaacf566ec8d0c420f72
https://doi.org/10.1097/dad.0000000000000533
رقم الانضمام: edsair.doi.dedup.....b7c1f9b7eadbfaacf566ec8d0c420f72
قاعدة البيانات: OpenAIRE
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