Primary extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type in the central nervous system (MZL CNS) presented as traumatic subdural hematoma and subarachnoid bleeding - case report
| العنوان: | Primary extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type in the central nervous system (MZL CNS) presented as traumatic subdural hematoma and subarachnoid bleeding - case report |
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| المؤلفون: | Wielisław Papierz, Piotr Kupnicki, Radzisław Kordek, Piotr Smolewski, Dorota Jesionek-Kupnicka, Elżbieta Płuciennik, Izabela Zawlik |
| المصدر: | Clinical neuropathology. 32(5) |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Pathology, medicine.medical_specialty, Lymphoid Tissue, medicine.medical_treatment, Pathology and Forensic Medicine, Diagnosis, Differential, Hematoma, Cervical lymphadenopathy, Parietal Lobe, medicine, Humans, Lymph node, Craniotomy, Mucous Membrane, business.industry, Brain Neoplasms, Head injury, General Medicine, Lymphoma, B-Cell, Marginal Zone, Middle Aged, Subarachnoid Hemorrhage, medicine.disease, Marginal zone, Temporal Lobe, Lymphoma, medicine.anatomical_structure, Hematoma, Subdural, Treatment Outcome, Neurology, Female, Neurology (clinical), medicine.symptom, business, Mucosa-associated lymphoid tissue |
| الوصف: | The study describes a very rare case of primary extranodal marginal zone Bcell lymphoma of the central nervous system (MZL CNS) with an unusual clinical and radiological presentation mimicking subarachnoid bleeding and subdural hematoma (SDH) after head injury. The patient presented symptoms which had commenced 3 weeks earlier: a gradually-progressing headache associated with periodic right-sided cramp of the face muscles and numbness of the right upper limb. During urgent craniotomy for drainage of the presumed SDH, a tumor mass histopathologically and immunohistochemically matching marginal zone B-cell lymphoma was found. Molecular analysis confirmed monoclonal immunoglobulin heavy chain gene (IgH) rearrangement; the patient had previously suspected nodal lymphoma because of cervical lymphadenopathy, but histopathological, immunohistochemical and molecular examination excluded malignant lymphoma. The patient underwent successful radiotherapy, and achieved complete response. At present, no evidence of either systemic disease or lymph node enlargement has been found. The recognition of an indolent type of lymphoma in a rare anatomical localization is very important due to the proper management of the patient. |
| تدمد: | 0722-5091 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53078afcae941b9733444e77392b00e https://pubmed.ncbi.nlm.nih.gov/23557903 |
| رقم الانضمام: | edsair.doi.dedup.....b53078afcae941b9733444e77392b00e |
| قاعدة البيانات: | OpenAIRE |
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