Early Efficacy and Safety Outcomes of Artificial Urinary Sphincter for Stress Urinary Incontinence Following Radical Prostatectomy or Benign Prostatic Obstruction Surgery: Results of a Large Multicentric Study
| العنوان: | Early Efficacy and Safety Outcomes of Artificial Urinary Sphincter for Stress Urinary Incontinence Following Radical Prostatectomy or Benign Prostatic Obstruction Surgery: Results of a Large Multicentric Study |
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| المؤلفون: | Franck Bruyère, Priscilla Léon, Xavier Gamé, Alice Pitout, Christian Saussine, L. Corbel, T. Tricard, Matthieu Durand, Thibaut Brierre, Baptiste Poussot, Grégoire Capon, Mehdi El-Akri, Tiffany Cousin, Jean-Nicolas Cornu, Daniel Chevallier, Damien Robin, Florian Beraud, Nicolas Hermieu, I. Bentellis, Jean-François Hermieu, Xavier Biardeau, Benoit Peyronnet, Pierre Lecoanet, Hervé Monsaint, Hugo Dupuis, Victor Gaillard |
| المساهمون: | Service d'urologie [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Centre Hospitalier Universitaire de Nice (CHU Nice), Service d'urologie [Rennes] = Urology [Rennes], Hôpital Pontchaillou-CHU Pontchaillou [Rennes], Service d'Urologie [Toulouse], CHU Toulouse [Toulouse], service d'urologie [CHU Bordeaux], CHU Bordeaux [Bordeaux], Departement d' Urologie, Université de Strasbourg, Departement d'Urology, Université de Strasbourg, AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service d'urologie Reims, Service d'Urologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service d'Urologie, andrologie et transplantation rénale [CHRU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Service d'urologie [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Hôpital Bretonneau, Clinique Oceane, Vannes, Clinique Plérin, Plérin, Clinique Pasteur,Royan, Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU) |
| المصدر: | European Urology Focus European Urology Focus, Elsevier, 2021, ⟨10.1016/j.euf.2021.09.006⟩ |
| بيانات النشر: | HAL CCSD, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Urology, medicine.medical_treatment, Urinary Incontinence, Stress, Population, Brachytherapy, 030232 urology & nephrology, Urinary incontinence, [SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology, Cystectomy, Artificial urinary sphincter, 03 medical and health sciences, 0302 clinical medicine, medicine, Clinical endpoint, Humans, education, ComputingMilieux_MISCELLANEOUS, Transurethral resection of the prostate, Retrospective Studies, Prostatectomy, education.field_of_study, business.industry, 3. Good health, Surgery, Treatment Outcome, Urinary Incontinence, 030220 oncology & carcinogenesis, Urinary Sphincter, Artificial, medicine.symptom, business |
| الوصف: | Background Artificial urinary sphincter (AUS) is the gold standard for the management of moderate to severe stress urinary incontinence (SUI) in the male population. While outcomes of this device in postprostatectomy incontinence (PPI) are widely described, those obtained for incontinence after benign prostatic obstruction (BPO) surgery remains poorly explored. Objective To compare continence outcomes after AUS implantation in a PPI population with those obtained in men incontinent after BPO surgery. Design, setting, and participants A retrospective review of all cases of AUS implantation between 2005 and 2020 in 16 different French centers was conducted. Only patients with primary implantation whose indication was moderate to severe SUI after prostatectomy or BPO surgery were included (excluding those with a history of radiation therapy, brachytherapy, cystectomy, high-intensity focused ultrasound therapy, or neurogenic disease). Outcome measurements and statistical analysis The primary endpoint was the rate of social continence (zero or one pad per day) at 3 mo. Complications were also noted within 90 d of implantation. Results and limitations A total of 417 patients were included in the PPI group and 50 in the BPO surgery group. Social continence rates at 3 mo were similar between the groups (79% vs 72%, p = 0.701). Complication rate was significantly higher in the BPO group (8% vs 18%, p = 0.044). The same was found for the Clavien-Dindo type 2 complication rate (20.6% vs 44.4%, p = 0.026). The retrospective nature and lack of precise definition of incontinence are the main limitations of this study. Conclusions This multicentric study strengthens the position of AUS as gold standard for SUI after radical prostatectomy. Comparable efficacy results were found for incontinence after BPO surgery, with nevertheless a higher rate of complications. Patient summary Artificial urinary sphincter represents the gold standard for the treatment of moderate to severe stress urinary incontinence. Efficacy results are comparable between postprostatectomy incontinence and incontinence after benign prostatic obstruction surgery. |
| اللغة: | English |
| تدمد: | 2405-4569 |
| DOI: | 10.1016/j.euf.2021.09.006⟩ |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c7a231c2edf1344232b4cd8af2a1cd https://hal-normandie-univ.archives-ouvertes.fr/hal-03457394 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....a6c7a231c2edf1344232b4cd8af2a1cd |
| قاعدة البيانات: | OpenAIRE |
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