Analysis of organic components in resin-modified pulp capping materials: critical considerations
| العنوان: | Analysis of organic components in resin-modified pulp capping materials: critical considerations |
|---|---|
| المؤلفون: | Einar Jensen, Vibeke B. Michelsen, Ulf Örtengren, Bo Wold Nilsen |
| المصدر: | European journal of oral sciences. 125(3) |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Ethylene glycol dimethacrylate, Glucuronates, Methacrylate, Mass spectrometry, Disaccharides, Calcium Hydroxide, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Polymer chemistry, para-Aminobenzoates, Humans, Aluminum Compounds, General Dentistry, Chromatography, High Pressure Liquid, Triethylene glycol, chemistry.chemical_classification, Silicates, Oxides, 030206 dentistry, Polymer, Calcium Compounds, UDMA, Pulp capping, Camphor, Resin Cements, Drug Combinations, chemistry, Methacrylates, Leaching (metallurgy), Pulp Capping and Pulpectomy Agents, Nuclear chemistry |
| الوصف: | The purpose of this study was to elucidate the organic composition and eluates of three resin-based pulp-capping materials in relation to their indications and safety data sheets. Uncured samples of Theracal LC, Ultra-Blend Plus, and Calcimol LC were investigated using gas chromatography-mass spectrometry (GC-MS) and ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). Identification/quantification of 7-d leachables of cured samples was performed using GC-MS for 2-hydroxyethyl methacrylate (HEMA), 2-(dimethylamino)ethyl methacrylate (DMAEMA), camphorquinone (CQ), ethylene glycol dimethacrylate (EGDMA), ethyl-4-(dimethylamino)benzoate (DMABEE), and triethylene glycol dimethacrylate (TEGDMA). A similar organic composition was found for Ultra-Blend and Calcimol; however, only Ultra-Blend is indicated for direct pulp-capping. In contrast to the other materials analysed, Theracal contained substances of high molecular weight. The safety data sheets of all materials were incomplete. We detected HEMA, CQ, and TEGDMA in eluates from Ultra-Blend and Calcimol, and it was considered that HEMA might have originated from decomposition of diurethane dimethacrylate (UDMA) in the GC-injector. For Theracal, additives associated with light curing (DMABEE and CQ) were detected in higher amounts (4.11 and 19.95 μg mm-2 ) than in the other materials. Pores were quantified in all samples by micro-computed tomography (micro-CT) analysis, which could influence leaching. The organic substances in the investigated materials might affect their clinical suitability as capping agents, especially for direct capping procedures. |
| تدمد: | 1600-0722 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a599ed20ffcb25078d36621f72380b2b https://pubmed.ncbi.nlm.nih.gov/28444854 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....a599ed20ffcb25078d36621f72380b2b |
| قاعدة البيانات: | OpenAIRE |
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