Microvascular changes after conbercept therapy in central retinal vein occlusion analyzed by optical coherence tomography angiography
| العنوان: | Microvascular changes after conbercept therapy in central retinal vein occlusion analyzed by optical coherence tomography angiography |
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| المؤلفون: | Ai-Qi Zhang, Guandi Chen, Wei Chi, Hui Chen, Lishi Su, Mingzhi Lu, Li-Mei Sun, Chenjin Jin, Yang Deng, Qi-Wen Zhong, Ying Lin, Li-Ting Zhong, Xiaojuan Cai, Shaochong Zhang |
| المصدر: | International Journal of Ophthalmology, Vol 12, Iss 5, Pp 802-808 (2019) |
| بيانات النشر: | Press of International Journal of Ophthalmology (IJO PRESS), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | medicine.medical_specialty, Visual acuity, genetic structures, foveal avascular zone, optical coherence tomography angiography, Conbercept, Perimeter, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Central retinal vein occlusion, lcsh:Ophthalmology, Clinical Research, Ophthalmology, vessel density, medicine, Macular edema, flow area, Plexus, macular edema, business.industry, central retinal vein occlusion, Retinal, Optical coherence tomography angiography, medicine.disease, eye diseases, chemistry, lcsh:RE1-994, 030221 ophthalmology & optometry, sense organs, medicine.symptom, business, conbercept |
| الوصف: | AIM: To investigate microvascular changes in eyes with central retinal vein occlusion (CRVO) complicated by macular edema before and after intravitreal conbercept injection and evaluate correlations between these changes and best-corrected visual acuity (BCVA) and retinal thickness. METHODS: Twenty-eight eyes of 28 patients with macular edema caused by CRVO were included in this retrospective study. All patients received a single intravitreal conbercept injection to treat macular edema. BCVA and the results of optical coherence tomography angiography (OCTA) automatic measurements of the vessel density in the superficial (SCP) and deep retinal capillary plexus (DCP), the foveal avascular zone (FAZ) area, the FAZ perimeter (PERIM), the vessel density within a 300-μm wide ring surrounding the FAZ (FD-300), the acircularity index (AI), the choriocapillaris flow area, and retinal thickness were recorded before and at one month after treatment and compared with the results observed in age- and sex- matched healthy subjects. RESULTS: The vessel density in the SCP and DCP, the FD-300, and the flow area of the choriocapillaris were all significantly lower in CRVO eyes than in healthy eyes, while the AI and retinal thickness were significantly higher (all P |
| اللغة: | English |
| تدمد: | 2227-4898 2222-3959 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5883b0df19f158420437eebd0dddfc7e http://www.ijo.cn/en_publish/2019/5/20190516.pdf |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5883b0df19f158420437eebd0dddfc7e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22274898 22223959 |
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