A comparative study of three-dimensional printing directions: The degradation and toxicological profile of a PLA/PHA blend
| العنوان: | A comparative study of three-dimensional printing directions: The degradation and toxicological profile of a PLA/PHA blend |
|---|---|
| المؤلفون: | Grazyna Adamus, Joanna Rydz, Mark R. Morris, Brian H. Johnston, Wanda Sikorska, Anna Hercog, Gouzhan Jiang, Jakub Wlodarczyk, Marta Musioł, Henryk Janeczek, H. R. Khan, Jennifer Gonzalez Ausejo, Michał Sobota, Iza Radecka, Marek Kowalczuk, Vinodh Kannappan, Keith R. Jones, Iwona Kwiecień |
| المصدر: | Polymer Degradation and Stability. 152:191-207 |
| بيانات النشر: | Elsevier BV, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Materials science, Thermoplastic, Polymers and Plastics, Biocompatibility, 3D printing, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Polyhydroxyalkanoates, Degradation, Tissue engineering, Materials Chemistry, Toxicity test, Cell proliferation, Layer orientation, chemistry.chemical_classification, Three-dimensional printing, business.industry, (bio)degradable polyester, bio)degradable polyester, Biodegradation, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 0104 chemical sciences, chemistry, Chemical engineering, Mechanics of Materials, Three dimensional printing, Degradation (geology), 0210 nano-technology, business |
| الوصف: | The use of biobased plastics is of great importance for many applications. Blending thermoplastic polylactide (PLA) with polyhydroxyalkanoate (PHA) enables the formulation of a more mechanically powerful material and this enables tailored biodegradation properties. In this study we demonstrate the 3D printing of a PLA/PHA blend as a potential candidate for biocompatible material applications. The filament for 3D printing consisted of PHA, which contains predominantly 3-hydroxybutyrate units and a small amount of 3-hydroxyvalerate units, as revealed by multistage mass spectrometry (ESI-MSn). This research found that the properties of 3D printed species before and during abiotic degradation are dependent on printing orientation. Furthermore, the 3D printed specimens exhibited good biocompatibility with HEK293 cells, indicating real promise as biological scaffolds for tissue engineering applications. |
| تدمد: | 0141-3910 |
| DOI: | 10.1016/j.polymdegradstab.2018.04.024 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5392e0c5363e38dc96a91e11ca3738f1 https://doi.org/10.1016/j.polymdegradstab.2018.04.024 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5392e0c5363e38dc96a91e11ca3738f1 |
| قاعدة البيانات: | OpenAIRE |
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