Chemical composition and antioxidant, anti-inflammatory, and antiproliferation activities of pomegranate (Punica granatum) flowers
| العنوان: | Chemical composition and antioxidant, anti-inflammatory, and antiproliferation activities of pomegranate (Punica granatum) flowers |
|---|---|
| المؤلفون: | Jalila Bekir, Amira Fterrich, Patricia Vicendo, Jalloul Bouajila, Mohamed Mars |
| المصدر: | Journal of medicinal food. 16(6) |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Antioxidant, DPPH, medicine.drug_class, medicine.medical_treatment, Anti-Inflammatory Agents, Medicine (miscellaneous), Flowers, Anti-inflammatory, Antioxidants, chemistry.chemical_compound, Botany, medicine, Humans, Gallic acid, Food science, Cell Proliferation, Lythraceae, Nutrition and Dietetics, ABTS, biology, Plant Extracts, Catechin, biology.organism_classification, Growth Inhibitors, chemistry, Punica, MCF-7 Cells, Quercetin |
| الوصف: | The chemical composition, antioxidant (DPPH and ABTS assays), anti-inflammatory (5-LOX), and cytotoxic (MCF-7) activities from flowers of seven pomegranate varieties (Punica granatum) were investigated. The highest phenolics (330.9±11.3 mg gallic acid equivalent/g dry weight (dw)), flavonoids (29.5±0.8 mg quercetin equivalent/g dw), tannins (30.6±0.6 mg catechin equivalent/g dw), and anthocyanins (0.70±0.03 mg cyanidin-3-glucoside equivalent/g dw) content were determined in the Chetoui (CH) variety. It was found that Garsi (GR) (IC₅₀=4.9±0.2 mg/L by ABTS assay) and Zaghwani (ZG) (IC₅₀=3.9±0.2 mg/L by ABTS assay) varieties exhibited the highest antioxidant activity. For the anti-inflammatory activity, all varieties were active; the ZH variety was the strongest (2.5±0.1 mg/L). The CH, ES, and RA pomegranate varieties were not active against human breast cancer cells MCF-7, whereas inhibition was more evident with extracts from ZH and GR varieties (IC₅₀=33.00±2.64 and 35.00±4.58 mg/L, respectively). Statistical analysis showed that the variety factor influenced significantly (P.01) the chemical composition and biological activities of pomegranate flowers. |
| تدمد: | 1557-7600 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365e697c06d05f23e369c4b66b27d58f https://pubmed.ncbi.nlm.nih.gov/23767863 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....365e697c06d05f23e369c4b66b27d58f |
| قاعدة البيانات: | OpenAIRE |
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