Prevalence and complications of hypouricemia in a general population: A large-scale cross-sectional study in Japan
| العنوان: | Prevalence and complications of hypouricemia in a general population: A large-scale cross-sectional study in Japan |
|---|---|
| المؤلفون: | Akira Ohtahara, Kazuhide Ogino, Einosuke Mizuta, Masanari Kuwabara, Ichiro Hisatome, Koichiro Niwa, Satoshi Miyazaki, Toshihiro Hamada |
| المصدر: | PLoS ONE, Vol 12, Iss 4, p e0176055 (2017) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Male, Cross-sectional study, lcsh:Medicine, 030204 cardiovascular system & hematology, Geographical Locations, chemistry.chemical_compound, Endocrinology, 0302 clinical medicine, Japan, Medicine and Health Sciences, Prevalence, Kidney Stones, 030212 general & internal medicine, Hypouricemia, lcsh:Science, education.field_of_study, Multidisciplinary, Developmental Nephrology, Middle Aged, Hospitals, Chemistry, Nephrology, Physical Sciences, Female, Kidney Diseases, Urinary Calculi, Anatomy, Research Article, Adult, medicine.medical_specialty, Asia, Renal Tubular Transport, Inborn Errors, Endocrine Disorders, Urology, Population, 03 medical and health sciences, Sex Factors, Internal medicine, Diabetes Mellitus, medicine, Humans, Risk factor, education, Retrospective Studies, business.industry, lcsh:R, Chemical Compounds, Biology and Life Sciences, Kidneys, Retrospective cohort study, Renal System, medicine.disease, Uric Acid, Surgery, Cross-Sectional Studies, Dyslipidemia, chemistry, Metabolic Disorders, People and Places, Uric acid, Kidney stones, lcsh:Q, business, Acids, Kidney disease |
| الوصف: | Backgrounds Hypouricemia was reported as a risk factor for exercise-induced acute renal injury (EIAKI) and urinary stones. However, the prevalence of kidney diseases among hypouricemic subjects has not been evaluated. This study was conducted to clarify the prevalence of hypouricemia and the association of hypouricemia with kidney diseases by using a large-scale Japanese population data. Methods This study is a retrospective cross-sectional study at the Center for Preventive Medicine, St. Luke’s International Hospital, Tokyo, Japan, and Sanin Rousai Hospital, Yonago, Japan. We analyzed the medical records of 90,143 Japanese subjects at the center in St. Luke’s International Hospital, Tokyo, and 4,837 subjects in Sanin Rousai Hospital, Yonago, who underwent annual regular health check-up between January 2004 and June 2010. We defined hypouricemia as serum uric acid level of ≤2.0 mg/dL. We checked the medical history of all the study subjects and compared the rates of complications including urinary stones and kidney diseases among those with or without hypouricemia. Results The prevalence of hypouricemia was 0.19% in St. Luke’s International Hospital, Tokyo, and 0.58% in Sanin Rousai Hospital, Yonago. The prevalence of hypouricemia in women was larger than that in men both in Tokyo (0.31% vs 0.068%, p |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20802638f26414e8f084111db137eb05 http://europepmc.org/articles/PMC5407834?pdf=render |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....20802638f26414e8f084111db137eb05 |
| قاعدة البيانات: | OpenAIRE |
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