Synthesis and photophysical, antibacterial studies of some novel molecular tweezers
العنوان: | Synthesis and photophysical, antibacterial studies of some novel molecular tweezers |
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المؤلفون: | Sivasamy Selvarani, Ayyavu Thirunarayanan, Perumal Rajakumar |
بيانات النشر: | Taylor & Francis, 2016. |
سنة النشر: | 2016 |
مصطلحات موضوعية: | biology, Stereochemistry, fungi, Bacillus cereus, 02 engineering and technology, General Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, medicine.disease_cause, biology.organism_classification, 01 natural sciences, Combinatorial chemistry, Fluorescence, 0104 chemical sciences, Absorbance, chemistry.chemical_compound, chemistry, Amide, medicine, Thiophene, 0210 nano-technology, Antibacterial activity, Escherichia coli, Molecular tweezers |
الوصف: | Zeroth and first generation dendritic wedges with thiophene amide as surface group and 1, 2, 3-triazole as bridging unit which can function as molecular tweezers are synthesised by both convergent and divergent approaches. All the synthesised dendritic wedges displayed the absorbance band between 256 and 294 nm and fluorescence maximum between 357 and 528 nm supporting their self complementary property. Dendritic wedge 5 showed better antibacterial activity than other dendritic wedges in the assay against the human pathogens viz Staphylococcus aureus, Escherichia coli, Bacillus cereus and Klebsiella pneumonia and the dentritic wedge 5 was also effective in the computational molecular docking studies. |
DOI: | 10.6084/m9.figshare.1579973 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a55c3f0ca14b2746f7070354f57e436 |
Rights: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....0a55c3f0ca14b2746f7070354f57e436 |
قاعدة البيانات: | OpenAIRE |
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