Effects of the Small Molecule Dorsomorphin on Intracellular Signaling
| العنوان: | Effects of the Small Molecule Dorsomorphin on Intracellular Signaling |
|---|---|
| المؤلفون: | Yasuhiro Ryu, Yoshinaka Shimizu, Mitsuhiro Kano, Ye Zhang, Kazutoshi Mizuno, Haruhide Hayashi, Hiroyasu Kanetaka, Tada Aki Kudo |
| المصدر: | Interface Oral Health Science 2011 ISBN: 9784431540694 |
| بيانات النشر: | Springer Japan, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | chemistry.chemical_compound, chemistry, AMPK, Signal transduction, Bone morphogenetic protein, Protein kinase A, Small molecule, Derivative (chemistry), Pyrazolopyrimidine, Intracellular, Cell biology |
| الوصف: | The small molecule dorsomorphin, also known as compound C, is a cell-permeable pyrazolopyrimidine derivative, which acts as a potent and reversible ATP-competitive inhibitor of AMP-activated protein kinase (AMPK). Recent studies indicated that several molecules with functions in other signaling pathways, including bone morphogenetic protein (BMP) signaling, are novel targets of dorsomorphin. This report focuses on two major targets of dorsomorphin and provides insight into the use of dorsomorphin in the analysis of intracellular signaling. |
| ردمك: | 978-4-431-54069-4 |
| DOI: | 10.1007/978-4-431-54070-0_31 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::829bf268bdf2f2e68562a58319e10f7a https://doi.org/10.1007/978-4-431-54070-0_31 |
| رقم الانضمام: | edsair.doi...........829bf268bdf2f2e68562a58319e10f7a |
| قاعدة البيانات: | OpenAIRE |
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