Separation, identification and quantitation of nitroglycerin and its metabolic or hydrolysis products
| العنوان: | Separation, identification and quantitation of nitroglycerin and its metabolic or hydrolysis products |
|---|---|
| المؤلفون: | Lei Shu Wu, Allan M. Burkman, Theodore D. Sokoloski, Chien Chin Wu |
| المصدر: | Journal of Chromatography A. 216:239-249 |
| بيانات النشر: | Elsevier BV, 1981. |
| سنة النشر: | 1981 |
| مصطلحات موضوعية: | Hydrolysis, Chromatography, Chemistry, Organic Chemistry, medicine, Organic chemistry, Acid hydrolysis, General Medicine, Biochemistry, Nitroglycerin, Analytical Chemistry, medicine.drug |
| الوصف: | The characteristics of high-performance liquid chromatographic and gas chromatographic-electron capture assay systems are described for the separation of nitroglycerin from its metabolic and hydrolysis products: 1,2-dinitroglycerin, 1,3-dinitroglycerin, 1-mononitroglycerin and 2-mononitroglycerin. The methods quantitate the amount of parent compound and its major metabolites and were used to measure the rate of acid hydrolysis of nitroglycerin and its dinitro compounds. Assignment of the several peaks in the chromatograms is unequivocal as shown through the use of synthesized metabolites and hydrolysis studies. |
| تدمد: | 0021-9673 |
| DOI: | 10.1016/s0021-9673(00)82352-3 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::588181688672423e249a068628b4846f https://doi.org/10.1016/s0021-9673(00)82352-3 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........588181688672423e249a068628b4846f |
| قاعدة البيانات: | OpenAIRE |
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