Single-step synthesis of kyotorphin in frozen solutions by chymotrypsin
| العنوان: | Single-step synthesis of kyotorphin in frozen solutions by chymotrypsin |
|---|---|
| المؤلفون: | M. Schuster, Hans-Dieter Jakubke, Mati Haga, Aavo Aaviksaar, Vello Tõugu, Helle Meos |
| المصدر: | Tetrahedron: Asymmetry. 4:1559-1564 |
| بيانات النشر: | Elsevier BV, 1993. |
| سنة النشر: | 1993 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Chymotrypsin, biology, Stereochemistry, Chemistry, Organic Chemistry, Single step, Peptide, Enzymatic synthesis, Combinatorial chemistry, Catalysis, Kyotorphin, Inorganic Chemistry, chemistry.chemical_compound, Aminolysis, biology.protein, Physical and Theoretical Chemistry |
| الوصف: | A novel method of Kyotorphin (H-Tyr-Arg-OH) synthesis without protecting and deprotecting procedures is described -α-chymotrypsin-catalyzed aminolysis of H-Tyr-OEt by H-Arg-OH in frozen mixtures. In this one-step process yields of the peptide product above 80% have been obtained. |
| تدمد: | 0957-4166 |
| DOI: | 10.1016/s0957-4166(00)80359-6 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::11f6735e9e83f34f0a50753f56a63caa https://doi.org/10.1016/s0957-4166(00)80359-6 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........11f6735e9e83f34f0a50753f56a63caa |
| قاعدة البيانات: | OpenAIRE |
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