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Factors associated with lack of antiretroviral adherence among adolescents in a reference centre in Rio de Janeiro, Brazil.

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العنوان: Factors associated with lack of antiretroviral adherence among adolescents in a reference centre in Rio de Janeiro, Brazil.
المؤلفون: Filho, L. F. B., Nogueira, S. A., Machado, E. S., Abreu, T. F., de Oliveira, R. H., Evangelista, L., Hofer, C. B.
المصدر: International Journal of STD & AIDS; Oct2008, Vol. 19 Issue 10, p685-688, 4p, 2 Charts
مصطلحات موضوعية: ANTIRETROVIRAL agents, PATIENT compliance, DISEASES in teenagers, LOGISTIC regression analysis, MULTIVARIATE analysis, CROSS-sectional method
مصطلحات جغرافية: RIO de Janeiro (Brazil), BRAZIL
مستخلص: The objective of this study was to describe the adherence to antiretroviral therapy (ART) among adolescents followed-up in Rio de Janeiro. This cross-sectional study included all adolescents (aged 10-19 years) followed at Instituto de Puericultura e Pediatria Martagão Gesteira and Hospital Universitário Clementino Fraga Filho. Adherence was determined by selfreport (number of missed ART doses in three days prior to the interview). Adherence was categorized as taking ⩾95% of the ARTs (adherent), or <95% (non-adherent). Variables related to demographics and treatment were evaluated and if P value ⩽0.15, they were selected for a logistic regression analysis. One hundred and one adolescents were interviewed. The mean time on ART was 91 months and the mean adherence was 94% of this, 21 were non-adherent, and 80 adherent. The risk factors associated with non-adherence were: if the patient was not concerned about ART, odds ratio (OR) = 3.47 (95% confidence interval [CI] = 1.13- 10.68); if they do not carry an extra dose of ART, OR = 6.63 (95% CI = 1.73-25.47); if a health-care worker taught them how to take ART, OR = 0.27 (95% CI = 0.08-0.93). Adherence among adolescents was higher than expected. Factors associated with lack of adherence were: interviewees being unaware of ARTs and lack of commitment to the treatment. Interventions involving these factors must be evaluated. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of STD & AIDS is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
قاعدة البيانات: Complementary Index
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