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1Academic Journal
المؤلفون: Wang, Linping, Pogue, Sylvain, Laamanen, Karoliina, Saarela, Jani, Poso, Antti, Laitinen, Tuomo, Valkonen, Jari P. T.
المساهمون: Department of Microbiology, Plant-Virus Interactions, Department of Agricultural Sciences, Institute for Molecular Medicine Finland, Biosciences, Viikki Plant Science Centre (ViPS), Plant Pathology and Virology, Plant Production Sciences
مصطلحات موضوعية: viral RNase III, RNA silencing suppressor, inhibitor identification, high-throughput screening, FRET, synergism, sweetpotato, SPCSV, EXOGENOUS APPLICATION, RIBONUCLEASE-III, MECHANISM, MOLECULES, BINDING, DSRNA, INTERFERENCE, RESISTANCE, ELIMINATION, DISCOVERY, Biochemistry, cell and molecular biology, General medicine, internal medicine and other clinical medicine
وصف الملف: application/pdf
Relation: This work was supported by the China Scholarship Council (State Scholarship Fund grant number 201406040060) and the Bill & Melinda Gates Foundation, Seattle, WA (NextGen Phytosanitation) . We thank Laura Turunen and Swapnil Potdar from the Institute for Molecular Medicine Finland (FIMM) for their technical help, Kristiina Himanen and Mirko Pavicicfrom the Plant Phenomics Research Group for support with the NaPPI platform, and Katrin Artola from the Plant Pathology Research Group for assistance and advice. The DDCB core facility (FIMM HTB unit) is supported by the University of Helsinki and Biocenter Finland. L.W. contributed to designing the study, performing the experiments, interpreting the data, and writing the draft of the paper. S.P. and J.S. contributed to performing the experiments and reviewing the paper. K.L. contributed to performing the experiments. A.P., T.L., and J.P.T.V. contributed to reviewing the paper. We declare that the results of this research are included in patent application FI 20205392, which could relate to financial interests.; Wang , L , Pogue , S , Laamanen , K , Saarela , J , Poso , A , Laitinen , T & Valkonen , J P T 2021 , ' In Vitro Identification and In Vivo Confirmation of Inhibitors for Sweet Potato Chlorotic Stunt Virus RNA Silencing Suppressor, a Viral RNase III ' , Journal of Virology , vol. 95 , no. 12 , ARTN e00107-21 . https://doi.org/10.1128/JVI.00107-21; ORCID: /0000-0001-7306-7175/work/95762630; ORCID: /0000-0002-3704-9911/work/95763480; ORCID: /0000-0002-0202-3703/work/95764300; http://hdl.handle.net/10138/331648; 58edce09-de77-4bc9-bdf7-0b5c123dcf22; 000656996900010
الاتاحة: http://hdl.handle.net/10138/331648
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المؤلفون: Jari P. T. Valkonen, Sylvain Poque, Jani Saarela, Tuomo Laitinen, Karoliina Laamanen, Antti Poso, Linping Wang
المساهمون: Department of Microbiology, Plant-Virus Interactions, Department of Agricultural Sciences, Institute for Molecular Medicine Finland, Biosciences, Viikki Plant Science Centre (ViPS), Plant Pathology and Virology, Plant Production Sciences
المصدر: Journal of Virology
مصطلحات موضوعية: 0106 biological sciences, MECHANISM, High-throughput screening, Immunology, RIBONUCLEASE-III, 01 natural sciences, Microbiology, high-throughput screening, Virus, 03 medical and health sciences, MOLECULES, In vivo, Virology, synergism, Vaccines and Antiviral Agents, BINDING, Ribonuclease III, RNA silencing suppressor, sweetpotato, ELIMINATION, 030304 developmental biology, 2. Zero hunger, chemistry.chemical_classification, INTERFERENCE, 0303 health sciences, biology, SPCSV, EXOGENOUS APPLICATION, Sweet potato feathery mottle virus, biology.organism_classification, In vitro, RNA silencing, Enzyme, inhibitor identification, chemistry, Insect Science, DISCOVERY, 3121 General medicine, internal medicine and other clinical medicine, biology.protein, FRET, 1182 Biochemistry, cell and molecular biology, viral RNase III, DSRNA, RESISTANCE, 010606 plant biology & botany