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1Academic Journal
المؤلفون: Freddy Ibanez, Joon Hyuk Suh, Yu Wang, Monique Rivera, Mamoudou Setamou, Lukasz L. Stelinski
المصدر: BMC Plant Biology, Vol 22, Iss 1, Pp 1-16 (2022)
مصطلحات موضوعية: Salicylic acid, Diaphorina citri, Plant defense, Metabolomics, Gene expression, Vector-host-pathogen interactions, Botany, QK1-989
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1471-2229
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2Academic Journal
المؤلفون: Parwez Ahmad, Chaima Bensaoud, Imen Mekki, Mujeeb Rehman, Michail Kotsyfakis
المصدر: Life; Volume 11; Issue 1; Pages: 56
مصطلحات موضوعية: ncRNA, lncRNA, vector–host–pathogen interactions
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Animal Science; https://dx.doi.org/10.3390/life11010056
الاتاحة: https://doi.org/10.3390/life11010056
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المؤلفون: Freddy Ibanez (11899748), Joon Hyuk Suh (11229378), Yu Wang (12152), Monique Rivera (11899751), Mamoudou Setamou (103890), Lukasz L. Stelinski (8136663)
مصطلحات موضوعية: Medicine, Microbiology, Ecology, Immunology, Infectious Diseases, Plant Biology, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Salicylic acid, Diaphorina citri, Plant defense, Metabolomics, Gene expression, Vector-host-pathogen interactions, Huanglongbing
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4Academic Journal
المؤلفون: Stockmal, Kelli A., Downs, Latoyia P., Davis, Ashley N., Kemp, Lisa K., Karim, Shahid, Morgan, Sarah E.
المصدر: Faculty Publications
مصطلحات موضوعية: The black-legged tick (Ixodes scapularis) is the primary vector for bacteria that cause Lyme disease (Borrelia burgdorferi), where numerous glycosylated tick proteins are involved at the interface of vector–host–pathogen interactions. Reducing the expression of key tick proteins, such as selenoprotein K (SelK), through RNA interference is a promising approach to reduce pathogen transmission, but efficient delivery of nucleic acids to arthropods has proven challenging. While cationic glycopolymers have been used as nonviral gene delivery vehicles in mammalian cells, their use in arthropod or insect gene transfection has not been established. In this study, statistical acrylamide-based cationic glycopolymers with glucose or galactose pendant groups were synthesized by reversible addition–fragmentation chain transfer polymerization, and the effects of the saccharide pendant group and cationic monomer loading on polymer cytotoxicity, RNA complexation, and SelK gene knockdown in ISE6 cells were evaluated. All polymers exhibited low cytotoxicity, yet RNA/copolymer complex cell uptake and gene knockdown were highly dependent on the saccharide structure and the N:P (amino to phosphate groups) ratio, Chemical Engineering, Engineering, Polymer Science
Relation: https://aquila.usm.edu/fac_pubs/19440; https://doi-org.lynx.lib.usm.edu/10.1021/acs.biomac.1c00824
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5
المؤلفون: Marco Di Luca, Carmine Fiorillo, Francesco Severini, Fabrizio Lombardo, Bruno Arcà, Alessio Colantoni, Vladimir Benes, Raffaele A. Calogero
المصدر: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)مصطلحات موضوعية: 0301 basic medicine, Saliva, mirnas, malaria, lcsh:Medicine, Mosquito Vectors, Disease Vectors, Salivary Glands, Article, vector-host-pathogen interactions, 03 medical and health sciences, 0302 clinical medicine, Immune system, stomatognathic system, Aedes, Immunity, Anopheles, microRNA, medicine, Animals, Humans, mosquito saliva, Salivary Proteins and Peptides, lcsh:Science, Pathogen, Genetics, Multidisciplinary, Salivary gland, biology, Sequence Analysis, RNA, lcsh:R, anopheles coluzzii, biology.organism_classification, MicroRNAs, 030104 developmental biology, medicine.anatomical_structure, Vector (epidemiology), Host-Pathogen Interactions, lcsh:Q, 030217 neurology & neurosurgery