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1Academic Journal
المؤلفون: Neefjes, Margot, Housmans, Bas A. C., Kaffa, Charlotte, Thielen, Nathalie G. M., Joosten, Leo A. B., van den Ende, Cornelia H. M., Vitters, Elly L., van den Akker, Guus G. H., Welting, Tim J. M., van Caam, Arjan P. M., van der Kraan, Peter M.
المصدر: Neefjes , M , Housmans , B A C , Kaffa , C , Thielen , N G M , Joosten , L A B , van den Ende , C H M , Vitters , E L , van den Akker , G G H , Welting , T J M , van Caam , A P M & van der Kraan , P M 2024 , ' Cell-integrated serum-induced signalling patterns can differentiate between hand and knee osteoarthritis patients ' , Rheumatology . https://doi.org/10.1093/rheumatology/keae555
مصطلحات موضوعية: stratification, osteoarthritis, serum, bioassay, endotype, BIOMARKERS
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2Academic Journal
المؤلفون: Steijns, Jessica S. J. J., Green, Daniel, Peeters, Laura C. W., Emans, Pieter J., Boymans, Tim A., Stassen, Roderick H., van den Akker, Guus G. H., Cremers, Andy, Jutten, Liesbeth M. C., Anderson, James R., Peffers, Mandy J., Caron, Marjolein M. J., Welting, Tim J. M.
المساهمون: Dutch Arthritis Association, Stichting the Weijerhorst, Horserace Betting Levy Board
المصدر: Connective Tissue Research ; volume 65, issue 6, page 486-496 ; ISSN 0300-8207 1607-8438
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3Academic Journal
المؤلفون: van den Akker, Guus G H, Chabronova, Alzbeta, Housmans, Bas A C, van der Vloet, Laura, Surtel, Don A M, Cremers, Andy, Marchand, Virginie, Motorin, Yuri, Caron, Marjolein M J, Peffers, Mandy J, Welting, Tim J M
المصدر: van den Akker , G G H , Chabronova , A , Housmans , B A C , van der Vloet , L , Surtel , D A M , Cremers , A , Marchand , V , Motorin , Y , Caron , M M J , Peffers , M J & Welting , T J M 2024 , ' TGF-β2 Induces Ribosome Activity, Alters Ribosome Composition and Inhibits IRES-Mediated Translation in Chondrocytes ' , International Journal of Molecular Sciences , vol. 25 , no. 9 , 5031 . https://doi.org/10.3390/ijms25095031
مصطلحات موضوعية: differential rRNA modification, ribosome heterogeneity, variation ribosome composition, Chondrocytes/metabolism drug effects, Ribosomes/metabolism, Humans, Protein Biosynthesis, RNA, Ribosomal/metabolism genetics, Transforming Growth Factor beta2/metabolism pharmacology, Internal Ribosome Entry Sites, Cell Line
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4Academic Journal
المؤلفون: Ripmeester, Ellen G. J., Steijns, Jessica S. J. J., Wijnands, Karolina A. P., Stassen, Roderick H. M. J., Pitelka, Vasek, Peeters, Laura C. W., Cremers, Andy, Astryde, Nzekui M. S. A., Chabronova, Alzbeta, Surtel, Don A. M., Emans, Pieter J., van den Akker, Guus G. H., van Rietbergen, Bert, van Rhijn, Lodewijk W., Caron, Marjolein M. J., Welting, Tim J. M.
المصدر: Ripmeester , E G J , Steijns , J S J J , Wijnands , K A P , Stassen , R H M J , Pitelka , V , Peeters , L C W , Cremers , A , Astryde , N M S A , Chabronova , A , Surtel , D A M , Emans , P J , van den Akker , G G H , van Rietbergen , B , van Rhijn , L W , Caron , M M J & Welting , T J M 2024 , ' The BMP7-Derived Peptide p[63-82] ....
مصطلحات موضوعية: articular cartilage, osteoarthritis, anterior cruciate ligament tear-partial meniscectomy, peptides, subchondral bone, cartilage degeneration, pain, ARTICULAR-CARTILAGE, WEIGHT-BEARING, SYNOVITIS, PATHOGENESIS, EFFICACY, DISEASE
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5Academic Journal
المؤلفون: Chabronova, Alzbeta, van den Akker, Guus G H, Housmans, Bas A C, Caron, Marjolein M J, Cremers, Andy, Surtel, Don A M, Wichapong, Kanin, Peffers, Mandy M J, van Rhijn, Marchand, Virginie, Motorin, Yuri, Welting, Tim J M
المساهمون: MS Orthopaedie Algemeen
مصطلحات موضوعية: 5.8S rRNA, Chondrocytes, Collagen type I, Preferential translation, Ribosome, rRNA epitranscriptomic regulation, Biomedical Engineering, Rheumatology, Orthopedics and Sports Medicine, Journal Article
وصف الملف: application/pdf
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6Academic Journal
المؤلفون: Ripmeester, Ellen G J, Welting, Tim J M, van den Akker, Guus G H, Surtel, Don A M, Steijns, Jessica S J, Cremers, Andy, van Rhijn, Lodewijk W, Caron, Marjolein M J
المصدر: Ripmeester , E G J , Welting , T J M , van den Akker , G G H , Surtel , D A M , Steijns , J S J , Cremers , A , van Rhijn , L W & Caron , M M J 2022 , ' BMP7 increases protein synthesis in SW1353 cells and determines rRNA levels in a NKX3-2-dependent manner ' , PLOS ONE , vol. 17 , no. 2 , e0263430 . https://doi.org/10.1371/journal.pone.0263430
مصطلحات موضوعية: Bone Morphogenetic Protein 7/pharmacology, Cell Proliferation/drug effects, Cells, Cultured, Chondrocytes/drug effects, Chondrogenesis/drug effects, Core Binding Factor Alpha 1 Subunit/genetics, Homeodomain Proteins/physiology, Humans, Promoter Regions, Genetic/drug effects, Protein Biosynthesis/drug effects, RNA, Ribosomal/genetics, Transcription Factors/physiology, Transcription, Up-Regulation/drug effects, PHOSPHORYLATION, RUNX2, REPRESSION, DNA, POLYMERASE-I TRANSCRIPTION, UBF, ARTICULAR CHONDROCYTES, EXPRESSION, GENE-TRANSCRIPTION, ACTS
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7Academic Journal
المؤلفون: Steinbusch, Mandy M F, van den Akker, Guus G H, Cremers, Andy, Witlox, Adhiambo M A, Staal, Heleen M, Peffers, Mandy J, van Rhijn, Lodewijk W, Caron, Marjolein M J, Welting, Tim J M
المصدر: Steinbusch , M M F , van den Akker , G G H , Cremers , A , Witlox , A M A , Staal , H M , Peffers , M J , van Rhijn , L W , Caron , M M J & Welting , T J M 2022 , ' Adaptation of the protein translational apparatus during ATDC5 chondrogenic differentiation ' , Non-Coding rna research , vol. 7 , no. 2 , pp. 55-65 . https://doi.org/10.1016/j.ncrna.2022.02.003
مصطلحات موضوعية: ATDC5, BINDING, CELL-LINE, Chondrogenic differentiation, GENE, IDENTIFICATION, INSULIN, MUTATIONS, NONCODING RNAS, RIBOSOME BIOGENESIS, Ribosome, SMALL NUCLEOLAR RNAS, Translation, YEAST, snoRNA
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8Academic Journal
المؤلفون: Niessink, Tom, Stassen, Roderick H M J, Kischkel, Brenda, Vuscan, Patricia, Emans, Peter J, van den Akker, Guus G H, Janssen, Matthijs, Joosten, Leo A B, Otto, Cees, Welting, Tim J M, Jansen, Tim L
المصدر: Niessink , T , Stassen , R H M J , Kischkel , B , Vuscan , P , Emans , P J , van den Akker , G G H , Janssen , M , Joosten , L A B , Otto , C , Welting , T J M & Jansen , T L 2024 , ' Discovery of calcite as a new pro-inflammatory calcium-containing crystal in human osteoarthritic synovial fluid ' , Osteoarthritis and Cartilage , vol. 32 , no. 10 , pp. 1261-1272 . https://doi.org/10.1016/j.joca.2024.05.004
مصطلحات موضوعية: Calcium crystals, Raman spectroscopy, biomarkers in osteoarthritis, crystal induced inflammation
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9Academic Journal
المؤلفون: Ripmeester, Ellen G. J., Caron, Marjolein M. J., van den Akker, Guus G. H., Steijns, Jessica, Surtel, Don A. M., Cremers, Andy, Peeters, Laura C. W., van Rhijn, Lodewijk W., Welting, Tim J. M.
المساهمون: ReumaNederland, Stichting the Weijerhorst
المصدر: Scientific Reports ; volume 11, issue 1 ; ISSN 2045-2322
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10Academic Journal
المؤلفون: van den Akker, Guus G. H., Chabronova, Alzbeta, Housmans, Bas A. C., van der Vloet, Laura, Surtel, Don A. M., Cremers, Andy, Marchand, Virginie, Motorin, Yuri, Caron, Marjolein M. J., Peffers, Mandy J., Welting, Tim J. M.
المصدر: International Journal of Molecular Sciences; May2024, Vol. 25 Issue 9, p5031, 18p
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11
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12Academic Journal
المؤلفون: van den Akker, Guus G. H., Eijssen, Lars M. T., Richardson, Stephen M., van Rhijn, Lodewijk W., Hoyland, Judith A., Welting, Tim J. M., Voncken, Jan Willem
المصدر: van den Akker , G G H , Eijssen , L M T , Richardson , S M , van Rhijn , L W , Hoyland , J A , Welting , T J M & Voncken , J W 2020 , ' A Membranome-Centered Approach Defines Novel Biomarkers for Cellular Subtypes in the Intervertebral Disc ' , Cartilage , vol. 11 , no. 2 , pp. 203-220 . https://doi.org/10.1177/1947603518764260
مصطلحات موضوعية: intervertebral disc, cell lines, nucleus pulposus, annulus fibrosus, biomarkers, membranome, NUCLEUS PULPOSUS CELLS, LOW-BACK-PAIN, EXTRACELLULAR-MATRIX, GENE-EXPRESSION, STEM-CELLS, IN-VITRO, PROGENITOR CELLS, CARTILAGE CELLS, FUNCTIONAL-ROLE
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13Electronic Resource
المؤلفون: MS Orthopaedie Algemeen, Chabronova, Alzbeta, van den Akker, Guus G H, Housmans, Bas A C, Caron, Marjolein M J, Cremers, Andy, Surtel, Don A M, Wichapong, Kanin, Peffers, Mandy M J, van Rhijn, Marchand, Virginie, Motorin, Yuri, Welting, Tim J M
URL:
https://doi.org/10.1016/j.joca.2022.12.010 http://hdl.handle.net/1874/448272 http://www.scopus.com/inward/record.url?scp=85146858891&partnerID=8YFLogxK
1063-4584
Osteoarthritis and Cartilage
31
3
374
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14Academic Journal
المؤلفون: Steinbusch, Mandy M. F., Caron, Marjolein M. J., Surtel, Don A. M., van den Akker, Guus G. H., van Dijk, Paul J., Friedrich, Franziska, Zabel, Bernhard, van Rhijn, Lodewijk W., Peffers, Mandy J., Welting, Tim J. M.
المصدر: Steinbusch , M M F , Caron , M M J , Surtel , D A M , van den Akker , G G H , van Dijk , P J , Friedrich , F , Zabel , B , van Rhijn , L W , Peffers , M J & Welting , T J M 2019 , ' The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion ' , Journal of Biological Chemistry , vol. 294 , no. 13 , pp. 5121-5136 . https://doi.org/10.1074/jbc.RA119.007356
مصطلحات موضوعية: cartilage biology, chondrogenesis, small nucleolar RNA (snoRNA), transforming growth factor beta (TGF-B), chemokine, secretion, C-X-C motif chemokine ligand 10, cartilage-hair hypoplasia, chondrogenic differentiation, RMRP snoRNA, viperin, INTERFERON-INDUCIBLE PROTEIN, MESENCHYMAL STEM-CELLS, RNASE MRP, GENE-EXPRESSION, MESSENGER-RNA, GROWTH-FACTOR, INHIBITION, GAMMA, ACTIVATION, MUTATIONS
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15Academic Journal
المؤلفون: de Kroon, Laurie M. G., Narcisi, Roberto, van den Akker, Guus G. H., Vitters, Elly L., Blaney Davidson, Esmeralda N., van Osch, Gerjo J. V. M., van der Kraan, Peter M.
المصدر: Scientific Reports ; volume 7, issue 1 ; ISSN 2045-2322
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16Academic Journal
المؤلفون: van den Akker, Guus G H, Surtel, Don A M, Cremers, Andy, Richardson, Stephen M, Hoyland, Judith A, van Rhijn, Lodewijk W, Voncken, Jan Willem, Welting, Tim J M
المصدر: van den Akker , G G H , Surtel , D A M , Cremers , A , Richardson , S M , Hoyland , J A , van Rhijn , L W , Voncken , J W & Welting , T J M 2016 , ' Novel Immortal Cell Lines Support Cellular Heterogeneity in the Human Annulus Fibrosus ' , PLoS ONE , vol. 11 , no. 1 , pp. e0144497 . https://doi.org/10.1371/journal.pone.0144497
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17Academic Journal
المؤلفون: van den Akker, Guus G H, Surtel, Don A M, Cremers, Andy, Hoes, Martijn F G A, Caron, Marjolein M, Richardson, Stephen M, Rodrigues-Pinto, Ricardo, van Rhijn, Lodewijk W, Hoyland, Judith A, Welting, Tim J M, Voncken, Jan Willem
المصدر: van den Akker , G G H , Surtel , D A M , Cremers , A , Hoes , M F G A , Caron , M M , Richardson , S M , Rodrigues-Pinto , R , van Rhijn , L W , Hoyland , J A , Welting , T J M & Voncken , J W 2016 , ' EGR1 controls divergent cellular responses of distinctive nucleus pulposus cell types ' , BMC Musculoskelet Disord , vol. 17 , no. 1 , pp. 124 . https://doi.org/10.1186/s12891-016-0979-x
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18Book
المؤلفون: van den Akker, Guus G. H., Cremers, Andy, Surtel, Donatus A. M., Voncken, Willem, Welting, Tim J. M.
المصدر: Methods in Molecular Biology ; Osteoporosis and Osteoarthritis ; page 41-52 ; ISSN 1064-3745 1940-6029 ; ISBN 9781071609880 9781071609897
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19
المؤلفون: van den Akker, Guus G H, Cremers, Andy, Surtel, Donatus A M, Voncken, Willem, Welting, Tim J M
المساهمون: RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation, Orthopedie, MUMC+: MA Orthopedie (9), RS: GROW - R4 - Reproductive and Perinatal Medicine, Moleculaire Genetica
المصدر: Methods in Molecular Biology, 2221, 41-52. Springer Nature Switzerland AG
مصطلحات موضوعية: Tissue Engineering, Nucleus Pulposus/cytology, Animals, Annulus Fibrosus/cytology, Humans, Intervertebral Disc/cytology, Cattle, musculoskeletal system, Cell Separation/methods
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20Academic Journal
المؤلفون: Spaapen, Frank, van den Akker, Guus G. H., Caron, Marjolein M. J., Prickaerts, Peggy, Rofel, Celine, Dahlmans, Vivian E. H., Surtel, Don A. M., Paulis, Yvette, Schweizer, Finja, Welting, Tim J. M., Eijssen, Lars M., Voncken, Jan Willem
المساهمون: Tsuji, Yoshiaki
المصدر: PLoS ONE ; volume 8, issue 3, page e58083 ; ISSN 1932-6203
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