المؤلفون: Bischoff, Nicolaj S, Undas, Anna K, van Bemmel, Greet, Briedé, Jacco J, van Breda, Simone G, Verhoeven, Jessica, Verbruggen, Sanne, Venema, Koen, Sijm, Dick T H M, de Kok, Theo M

المصدر: Bischoff , N S , Undas , A K , van Bemmel , G , Briedé , J J , van Breda , S G , Verhoeven , J , Verbruggen , S , Venema , K , Sijm , D T H M & de Kok , T M 2025 , ' Investigating the ROS Formation and Particle Behavior of Food-Grade Titanium Dioxide (E171) in the TIM-1 Dynamic Gastrointestinal Digestion Model ' , Nanomaterials , vol. 15 , no. 1 , 8 . https://doi.org/10.3390/nano15010008

مصطلحات موضوعية: E171, ROS, agglomeration, human gastrointestinal digestion, physicochemical characterization, titanium dioxide

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/494a895a-6aee-496c-9952-d83dad85ec8d
https://doi.org/10.3390/nano15010008

المؤلفون: Sinha, Rashmi, Zhao, Ni, Goedert, James J, Byrd, Doratha A, Wan, Yunhu, Hua, Xing, Hullings, Autumn G, Knight, Rob, van Breda, Simone, Mathijs, Karen, de Kok, Theo M, Ward, Mary H, members, PHYTOME consortium, Pieters, Harm-Jan, Sági-Kiss, Virág, Kuhnle, Gunter G, Georgiadis, Panagiotis, Saccani, Giovanna, Parolari, Giovanni, Virgili, Roberta, Hemke, Gert, Hung, Yung, Verbeke, Wim, Masclee, Ad A, Vleugels-Simon, Carla B, van Bodegraven, Adriaan A, Dobbelaere, Dirk, Vandewynkel, Anneleen, van der Kruijk, Richard, Egberts, Frans, van Helvoirt, Jan-Hein

مصطلحات موضوعية: Biological Sciences, Environmental Sciences, Chemical Sciences, Digestive Diseases, Nutrition, Cancer, Oral and gastrointestinal, Diet, Drinking Water, Humans, Meat, Nitrates, Nitrites, RNA, Ribosomal, 16S, Processed meat, Water nitrate, Nitrite, Oral and fecal microbiome, Phytochemicals, PHYTOME consortium members, Toxicology, Biological sciences, Chemical sciences, Environmental sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/35z9s97n

المؤلفون: He, Yueqin, DeBenedictis, Julia Nicole, Caiment, Florian, van Breda, Simone G. J., de Kok, Theo M. C. M.

المصدر: Scientific Reports ; volume 14, issue 1 ; ISSN 2045-2322

الاتاحة: https://doi.org/10.1038/s41598-024-53927-y
https://www.nature.com/articles/s41598-024-53927-y.pdf
https://www.nature.com/articles/s41598-024-53927-y

المؤلفون: DeBenedictis, Julia N., Murrell, Courtney, Hauser, Duncan, van Herwijnen, Marcel, Elen, Bart, de Kok, Theo M., van Breda, Simone G.

المصدر: DeBenedictis , J N , Murrell , C , Hauser , D , van Herwijnen , M , Elen , B , de Kok , T M & van Breda , S G 2024 , ' Effects of Different Combinations of Phytochemical-Rich Fruits and Vegetables on Chronic Disease Risk Markers and Gene Expression Changes : Insights from the MiBLEND Study, a Randomized Trial ' , Antioxidants , vol. 13 , no. 8 , 915 . https://doi.org/10.3390/antiox13080915

مصطلحات موضوعية: phytochemicals, prevention, disease risk, synergy, fruit, vegetables, transcriptomics, DNA damage, antioxidant, nutrigenomics, INTIMA-MEDIA THICKNESS, DNA-DAMAGE, CAROTID ATHEROSCLEROSIS, ANTIOXIDANT CAPACITY, DIETARY-INTAKE, CARDIOVASCULAR-DISEASE, LIPID-PEROXIDATION, BRUSSELS-SPROUTS, BETA-CAROTENE, PLASMA-LEVELS

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/c377d5ef-1426-4b39-82a9-1ec791cb7105
https://doi.org/10.3390/antiox13080915

المؤلفون: DeBenedictis, Julia N, Baars, Esther, Ochoteco-Asensio, Juan, van Breda, Simone G, de Kok, Theo M

المصدر: DeBenedictis , J N , Baars , E , Ochoteco-Asensio , J , van Breda , S G & de Kok , T M 2024 , ' Genetic Variability Impacts Genotoxic and Transcriptome Responses in the Human Colon after the Consumption of Processed Red Meat Products and Those with Added Phytochemical Extracts ' , Nutrients , vol. 16 , no. 3 , 425 . https://doi.org/10.3390/nu16030425

مصطلحات موضوعية: colorectal cancer prevention, genetic variability, nutrigenomics, personalized nutrition, phytochemicals, Humans, Meat Products/analysis, DNA Adducts/genetics metabolism, Transcriptome, DNA Damage, Meat/analysis, Red Meat/analysis, Nitroso Compounds/metabolism, Colon/metabolism

Relation: https://cris.maastrichtuniversity.nl/en/publications/bd5bd4ad-e411-4fda-9652-51c0f96aded6

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/bd5bd4ad-e411-4fda-9652-51c0f96aded6
https://doi.org/10.3390/nu16030425

المؤلفون: Bischoff, Nicolaj S., Undas, Anna K., van Bemmel, Greet, Briedé, Jacco J., van Breda, Simone G., Verhoeven, Jessica, Verbruggen, Sanne, Venema, Koen, Sijm, Dick T. H. M., de Kok, Theo M.

المصدر: Nanomaterials (2079-4991); Jan2025, Vol. 15 Issue 1, p8, 18p

مصطلحات موضوعية: ELECTRON paramagnetic resonance spectroscopy, TITANIUM dioxide, REACTIVE oxygen species, TRANSMISSION electron microscopy, LIGHT scattering

المؤلفون: Bischoff, Nicolaj S, Proquin, Héloïse, Jetten, Marlon J, Schrooders, Yannick, Jonkhout, Marloes C M, Briedé, Jacco J, van Breda, Simone G, Jennen, Danyel G J, Medina-Reyes, Estefany I, Delgado-Buenrostro, Norma L, Chirino, Yolanda I, van Loveren, Henk, de Kok, Theo M

المصدر: Bischoff , N S , Proquin , H , Jetten , M J , Schrooders , Y , Jonkhout , M C M , Briedé , J J , van Breda , S G , Jennen , D G J , Medina-Reyes , E I , Delgado-Buenrostro , N L , Chirino , Y I , van Loveren , H & de Kok , T M 2023 , ' Correction: Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer. ....

Relation: https://cris.maastrichtuniversity.nl/en/publications/f8bed257-80fd-40a0-a638-80e3b7f9ac24

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/f8bed257-80fd-40a0-a638-80e3b7f9ac24
https://doi.org/10.3390/nano13212888

المؤلفون: DeBenedictis, Julia N., Murrell, Courtney, Hauser, Duncan, van Herwijnen, Marcel, Elen, Bart, de Kok, Theo M., van Breda, Simone G.

المصدر: Antioxidants; Aug2024, Vol. 13 Issue 8, p915, 37p

مصطلحات موضوعية: GENE expression, DNA repair, OXIDANT status, GENETIC transcription, CELLULAR signal transduction, ANTHOCYANINS, DNA damage

المؤلفون: van Breda, Simone G., Mathijs, Karen, Pieters, Harm‐Jan, Sági‐Kiss, Virág, Kuhnle, Gunter G., Georgiadis, Panagiotis, Saccani, Giovanna, Parolari, Giovanni, Virgili, Roberta, Sinha, Rashmi, Hemke, Gert, Hung, Yung, Verbeke, Wim, Masclee, Ad A., Vleugels‐Simon, Carla B., van Bodegraven, Adriaan A., de Kok, Theo M.

وصف الملف: text

Relation: https://centaur.reading.ac.uk/99941/1/mnfr.202001214.pdf; van Breda, S. G. orcid:0000-0003-1421-8214 , Mathijs, K., Pieters, H.‐J., Sági‐Kiss, V., Kuhnle, G. G. orcid:0000-0002-8081-8931 , Georgiadis, P., Saccani, G., Parolari, G., Virgili, R., Sinha, R., Hemke, G., Hung, Y., Verbeke, W., Masclee, A. A., Vleugels‐Simon, C. B., van Bodegraven, A. A. and de Kok, T. M. (2021) Replacement of nitrite in meat products by natural bioactive compounds results in reduced exposure to N‐Nitroso compounds: the PHYTOME project. Molecular Nutrition & Food Research, 65 (20). p. 2001214. ISSN 1613-4125 doi: https://doi.org/10.1002/mnfr.202001214

الاتاحة: https://centaur.reading.ac.uk/99941/
https://centaur.reading.ac.uk/99941/1/mnfr.202001214.pdf

المؤلفون: Bischoff, Nicolaj S, de Kok, Theo M, Sijm, Dick T H M, van Breda, Simone G, Briedé, Jacco J, Castenmiller, Jacqueline J M, Opperhuizen, Antoon, Chirino, Yolanda I, Dirven, Hubert, Gott, David, Houdeau, Eric, Oomen, Agnes G, Poulsen, Morten, Rogler, Gerhard, van Loveren, Henk

المصدر: Bischoff , N S , de Kok , T M , Sijm , D T H M , van Breda , S G , Briedé , J J , Castenmiller , J J M , Opperhuizen , A , Chirino , Y I , Dirven , H , Gott , D , Houdeau , E , Oomen , A G , Poulsen , M , Rogler , G & van Loveren , H 2021 , ' Possible Adverse Effects of Food Additive E171 (Titanium Dioxide) Related to Particle Specific Human Toxicity, Including the Immune System ' , International Journal ....

وصف الملف: application/pdf

Relation: https://orbit.dtu.dk/en/publications/a9da1039-1954-45f9-a5d2-cbb08623b2df

الاتاحة: https://orbit.dtu.dk/en/publications/a9da1039-1954-45f9-a5d2-cbb08623b2df
https://doi.org/10.3390/ijms22010207
https://backend.orbit.dtu.dk/ws/files/237768057/ijms_22_00207.pdf

المؤلفون: DeBenedictis, Julia N., Baars, Esther, Ochoteco-Asensio, Juan, van Breda, Simone G., de Kok, Theo M.

المصدر: Nutrients; Feb2024, Vol. 16 Issue 3, p425, 30p

المؤلفون: Bischoff, Nicolaj S, Proquin, Héloïse, Jetten, Marlon J, Schrooders, Yannick, Jonkhout, Marloes C M, Briedé, Jacco J, van Breda, Simone G, Jennen, Danyel G J, Medina-Reyes, Estefany I, Delgado-Buenrostro, Norma L, Chirino, Yolanda I, van Loveren, Henk, de Kok, Theo M

URL الوصول: https://explore.openaire.eu/search/publication?articleId=narcis______::4d44ba4aaac7e2a2f75910902a3148de
http://hdl.handle.net/10029/626711

المؤلفون: van Breda, Simone G., Mathijs, Karen, Sági-Kiss, Virág, Kuhnle, Gunter G., van der Veer, Ben, Jones, Rena R., Sinha, Rashmi, Ward, Mary H., de Kok, Theo M.

المصدر: Environmental Health, 18(1), 87, (2019-10-17)

مصطلحات موضوعية: Nitrate, Nitrite, Drinking water, Processed red and unprocessed white meat, Human dietary intervention study, N-nitroso compounds, Genotoxicity, Vitamin C, Endogenous nitrosation

Relation: https://zenodo.org/communities/fp7-bmc; https://zenodo.org/communities/eu; oai:zenodo.org:3514490

الاتاحة: https://doi.org/10.1186/s12940-019-0525-z

المؤلفون: Berends, Julia E., van den Berg, Lauri M. M., Guggeis, Martina A., Henckens, Mikki F. T., Hossein, Israt J., de Joode, Minke E. J. R., Zamani, Hossy, van Pelt, Kirsten A. A. J., Beelen, Nicky A., Kuhnle, Gunter G., de Kok, Theo M. C. C., Van Breda, Simone G. J.

وصف الملف: text

Relation: https://centaur.reading.ac.uk/84714/1/ijms-20-02277%20%281%29.pdf; Berends, J. E., van den Berg, L. M. M., Guggeis, M. A., Henckens, M. F. T., Hossein, I. J., de Joode, M. E. J. R., Zamani, H., van Pelt, K. A. A. J., Beelen, N. A., Kuhnle, G. G. orcid:0000-0002-8081-8931 , de Kok, T. M. C. C. and Van Breda, S. G. J. (2019) Consumption of nitrate-rich beetroot juice with or without vitamin C supplementation increases the excretion of urinary nitrate, nitrate, and N-nitroso compounds in humans. International Journal of Molecular Sciences, 20 (9). ISSN 1422-0067 doi: https://doi.org/10.3390/ijms20092277

الاتاحة: https://centaur.reading.ac.uk/84714/
https://centaur.reading.ac.uk/84714/1/ijms-20-02277%20%281%29.pdf

المؤلفون: van Breda, Simone G. J., Briede, Jacob J., de Kok, Theo M. C. M.

المصدر: van Breda , S G J , Briede , J J & de Kok , T M C M 2019 , ' Improved Preventive Effects of Combined Bioactive Compounds Present in Different Blueberry Varieties as Compared to Single Phytochemicals ' , Nutrients , vol. 11 , no. 1 , 61 . https://doi.org/10.3390/nu11010061

مصطلحات موضوعية: disease risk reduction, blueberry extracts, (combinations of) phytochemicals, antioxidant capacity, gene expression profiles, DNA-DAMAGE, RADICAL FORMATION, MECHANISMS, FRUIT, IMPACT, CANCER

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/f3a85dbe-c94e-4261-977b-8d6d0d0fcd86
https://doi.org/10.3390/nu11010061

المؤلفون: Rosier, Bob T., Takahashi, Nobuhiro, Zaura, Egija, Krom, Bastiaan P., Martínez-Espinosa, Rosa María, van Breda, Simone G.J., Marsh, Philip D., Mira, Alex

المساهمون: Universidad de Alicante. Departamento de Agroquímica y Bioquímica, Bioquímica Aplicada/Applied Biochemistry (AppBiochem)

المصدر: Rosier, B T, Takahashi, N, Zaura, E, Krom, B P, MartÍnez-Espinosa, R M, van Breda, S G J, Marsh, P D & Mira, A 2022, ' The Importance of Nitrate Reduction for Oral Health ', Journal of Dental Research, vol. 101, no. 8, pp. 887-897 . https://doi.org/10.1177/00220345221080982

مصطلحات موضوعية: SALIVARY NITRATE, microbiome, Oral Health, METABOLISM, Dental Caries, Nitric Oxide, microbial ecology, SDG 3 - Good Health and Well-being, halitosis, Humans, ACIDIFIED NITRITE, Saliva, General Dentistry, Nitrites, Periodontal Diseases, caries, NITRIC-OXIDE, Nitrates, Bacteria, Bioquímica y Biología Molecular, RESILIENCE, periodontal diseases/periodontitis, DIETARY NITRATE, probiotics, PERIODONTITIS

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc53c498ee879ca4df679814c2b523ab
https://doi.org/10.1177/00220345221080982

المؤلفون: Briede, Jacob J., Deferme, Lize, Wolters, Jarno E. J., Claessen, Sandra M. H., van den Beucken, Twan, Wagner, Richard J., van Breda, Simone G., Kleinjans, Jos C. S.

المصدر: Briede , J J , Deferme , L , Wolters , J E J , Claessen , S M H , van den Beucken , T , Wagner , R J , van Breda , S G & Kleinjans , J C S 2018 , ' A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases ' , Toxicology in Vitro , vol. 48 , pp. 318-328 . https://doi.org/10.1016/j.tiv.2018.02.006

مصطلحات موضوعية: tert-Butyl hydroperoxide, 5-Hydroxymethylcytosine, 5-Methylcytosine, Differentially expressed genes, Serine-threonine kinases, HepG2 cells, EMBRYONIC STEM-CELLS, HEPATOCELLULAR-CARCINOMA, DNA-DAMAGE, LIVER CARCINOGENESIS, DETOXIFYING ENZYMES, TET PROTEINS, METHYLATION, SURVIVAL, CANCER

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/207e0e71-6e7f-4923-aa43-261ef38a9ae7
https://doi.org/10.1016/j.tiv.2018.02.006

المؤلفون: Wolters, Jarno E. J., van Breda, Simone G. J., Grossmann, Jonas, Fortes, Claudia, Caiment, Florian, Kleinjans, Jos C. S.

المصدر: Wolters , J E J , van Breda , S G J , Grossmann , J , Fortes , C , Caiment , F & Kleinjans , J C S 2018 , ' Integrated 'omics analysis reveals new drug-induced mitochondrial perturbations in human hepatocytes ' , Toxicology Letters , vol. 289 , pp. 1-13 . https://doi.org/10.1016/j.toxlet.2018.02.026

مصطلحات موضوعية: Steatosis, Mitochondrial dysfunction, Primary human hepatocytes, Epigenomics, Transcriptomics, Proteomics, VALPROIC ACID METABOLISM, HISTONE DEACETYLASE, DNA METHYLATION, HEPATOCELLULAR-CARCINOMA, OXIDATIVE STRESS, QUALITY-CONTROL, NUCLEAR, CELLS, DYSFUNCTION, MECHANISMS

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/0b19343f-b48a-4a09-ab3d-2df400aeb9fc
https://doi.org/10.1016/j.toxlet.2018.02.026

المؤلفون: Ward, Mary H., Jones, Rena R., Brender, Jean D., de Kok, Theo M., Weyer, Peter J., Nolan, Bernard T., Villanueva, Cristina M., van Breda, Simone G.

المصدر: Ward , M H , Jones , R R , Brender , J D , de Kok , T M , Weyer , P J , Nolan , B T , Villanueva , C M & van Breda , S G 2018 , ' Drinking Water Nitrate and Human Health : An Updated Review ' , International Journal of Environmental Research and Public Health , vol. 15 , no. 7 , 1557 . https://doi.org/10.3390/ijerph15071557

مصطلحات موضوعية: drinking water, nitrate, cancer, adverse reproductive outcomes, methemoglobinemia, thyroid disease, endogenous nitrosation, N-nitroso compounds, DISINFECTION BY-PRODUCTS, NEURAL-TUBE DEFECTS, NITRIC-OXIDE SYNTHASE, NITROSATABLE DRUG EXPOSURE, CHILDHOOD BRAIN-TUMORS, COLORECTAL-CANCER RISK, BIRTH-DEFECTS, UNITED-STATES, ENDOGENOUS FORMATION, United States, Humans, Nitrates/toxicity, Thyroid Diseases/chemically induced, Neural Tube Defects/chemically induced, Female, Nitroso Compounds/metabolism, Environmental Monitoring, Europe, Pregnancy, Animals, Water Pollutants, Chemical/toxicity

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/8fb6f1a4-2d79-4bb3-8816-6e6d7f077373
https://doi.org/10.3390/ijerph15071557

المؤلفون: Limonciel, Alice, van Breda, Simone G., Jiang, Xiaoqi, Tredwell, Gregory D., Wilmes, Anja, Aschauer, Lydia, Siskos, Alexandros P., Sachinidis, Agapios, Keun, Hector C., Kopp-Schneider, Annette, de Kok, Theo M., Kleinjans, Jos C. S., Jennings, Paul

المصدر: Limonciel , A , van Breda , S G , Jiang , X , Tredwell , G D , Wilmes , A , Aschauer , L , Siskos , A P , Sachinidis , A , Keun , H C , Kopp-Schneider , A , de Kok , T M , Kleinjans , J C S & Jennings , P 2018 , ' Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens ' , Frontiers in Genetics , vol. 9 , 558 . https://doi.org/10.3389/fgene.2018.00558

مصطلحات موضوعية: recovery, persistence, epigenomics, stress responses, ochratoxin A, potassium bromate, nephrotoxicity, metabolomics, OCHRATOXIN-A, INDUCED CYTOTOXICITY, OXIDATIVE STRESS, FOOD-ADDITIVES, DNA-DAMAGE, IN-VITRO, TOXICITY, KIDNEY, RAT

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/8cf8eec8-9366-4c19-8fc1-5d7644490272
https://doi.org/10.3389/fgene.2018.00558