المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/presentation/S1_Fig_-/17710667

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.s001

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/presentation/HLX10_and_PD-1_contact_/17710679

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.s004

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/presentation/NCI-H292_hPBMC_co-mixture_model_/17710676

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.s003

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/presentation/MC-38_in_vivo_model_/17710670

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.s002

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/journal_contribution/Supplemental_material_and_methods_/17710682

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.s005

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/Binding_and_PD-L1_2_ligand_blocking_of_HLX10_/17710697

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g003

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/ELISA_binding_of_HLX10_to_PD-1_ECD_from_different_species_/17710694

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g002

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/Binding_and_PD-L1_ligand_blocking_of_clG4_and_Nivolumab_antibodies_/17710691

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g001

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/IL-2_and_IFN-_dose_response_curve_of_HLX10_in_a_mixed_DC_CD4_T-cell_MLR_assay_/17710700

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g004

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/Tumor_growth_inhibition_of_HLX10_in_HT-29-_and_NCI-H292_-hPBMC_co-mixture_xenograft_mice_models_/17710703

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g005

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/Growth_of_EMT_breast_cancer_syngeneic_tumors_was_measured_in_PD-1_knock-in_mice_following_6_injections_gray_area_of_either_vehicle_buffer_10_mL_Kg_or_HLX10_15_mg_kg_and_2_weeks_after_the_last_dose_day_25_n_10_mice_group_/17710709

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g006

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/HLX10_i_in_vivo_i_antitumor_activity_compared_to_that_of_Nivolumab_and_Pembrolizumab_/17710712

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g007

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/Interaction_between_HLX10_and_hPD-1_/17710721

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g009

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/Binding_epitope_of_HLX10_overlaps_with_PD-L1_and_PD-L2_/17710724

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g010

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/Anti-tumor_activity_of_HLX10_and_Bevacizumab_in_HT-29_and_NCI-H292_hPBMC_co-mixture_xenograft_models_/17710715

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g008

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/Comparison_of_binding_epitope_of_HLX10_with_Pembrolizumab_and_Nivolumab_/17710727

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g011

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/Human_PD-1_receptor_occupancy_/17710733

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g013

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/figure/PD-1_receptor_occupancy_and_PK_profiles_/17710730

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.g012

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/dataset/Kinetics_and_binding_affinities_of_anti-PD-1_antibody_to_human_PD-1_determined_by_BLI_/17710736

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.t001

المؤلفون: Hassan Issafras (11681550), Shilong Fan (9625883), Chi-Ling Tseng (11681538), Yunchih Cheng (11890934), Peihua Lin (11890937), Lisa Xiao (11890940), Yun-Ju Huang (9605739), Chih-Hsiang Tu (1435027), Ya-Chin Hsiao (288524), Min Li (12799), Yen-Hsiao Chen (11890943), Chien-Hsin Ho (2211316), Ou Li (101542), Yanling Wang (309043), Sandra Chen (11890946), Zhenyu Ji (6291644), Eric Zhang (4459516), Yi-Ting Mao (2613853), Eugene Liu (1271409), Shumin Yang (847715), Weidong Jiang (468041)

مصطلحات موضوعية: Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, increased functional activities, future therapeutic candidates, fully humanized igg, opposite heavy chain, novel monoclonal antibodies, novel antibody formats, 1 inhibitors remains, 1 ), represents, several tumor models, div >< p, 1 receptor recognition, elucidate hlx10 ’, novel anti pd, monoclonal antibody, 1 receptor, recognition compared, light chain, tumor elimination, tumor activity, hlx10 ’, weight compounds, vivo <, vitro <, unprecedented results

Relation: https://figshare.com/articles/dataset/Data_collection_and_refinement_statistics_/17710739

الاتاحة: https://doi.org/10.1371/journal.pone.0257972.t002