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المؤلفون: Cheng Luo, Jianpeng Liu, Ming Liu, Quan Zhao, Xinyu Li, Yichen Xu, Xiaming Pang, Jingru Ge, Ying Wang
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, translation control, HRI, Heme-Regulated Inhibitor, Protein-Arginine N-Methyltransferases, Methyltransferase, SCD, Sickle Cell Disease, Five prime untranslated region, Gene Expression, beta-Globins, Biochemistry, ATF4, Activating Transcription Factor 4, Transcription (biology), hemic and lymphatic diseases, DDX3, Dead-Box Polypetide 3, PRMT1, Protein Arginine Methyltransferase 1, gamma-Globins, Fetal Hemoglobin, Translation (biology), Cell biology, HbA, Adult Hemoglobin, 5’UTR, 5’ Untranslated Region, Research Article, PABP1, Polyadenylate-Binding Protein 1, uORF, upstream Open Reading Frame, ISR, Integrated Stress Response, Activating Transcription Factor 4, Biology, γ-globin, 03 medical and health sciences, Upstream open reading frame, Integrated stress response, Humans, ATIS, Alternative Translation Initiation Sites, protein arginine methyltransferase 1 (PRMT1), Molecular Biology, ATP2A2, ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 2, 030102 biochemistry & molecular biology, ATF4, Cell Biology, Methyltransferases, PIC, Preinitiation Complex, β-hemoglobinopathies, Repressor Proteins, upstream open reading frame (uORF), 030104 developmental biology, HEK293 Cells, Gene Expression Regulation, Protein Biosynthesis, eIF2α, Translation Initiation Factor 2, HbF, Fetal Hemoglobin, K562 Cells
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المؤلفون: Mockenhaupt, Stefan, Makeyev, Eugene V.
المساهمون: School of Biological Sciences
المصدر: Seminars in Cell & Developmental Biology
مصطلحات موضوعية: nt, nucleotide, NMTR, nonsense-mediated translational repression, Alternative pre-mRNA splicing, NRE, nuclear retention and elimination, uORF, upstream open reading frame, RNA Stability, Development, RUST, regulated unproductive splicing and translation, Article, Evolution, Molecular, Morphogenesis, RNA Precursors, Animals, Humans, mRNA stability, APA, alternative cleavage and polyadenylation, ARE, AU-rich element, Models, Genetic, NMD, nonsense-mediated decay, A3E, alternative 3′ terminal exon, Gene Expression Regulation, Developmental, PTC, premature termination codon, Cell Biology, Translational regulation, Alternative Splicing, IR, intron retention, Protein Biosynthesis, mRNA localization, AS, alternative splicing, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Miriam Cnop, Sanna Toivonen, Paraskevi Salpea, Mariana Igoillo-Esteve
المصدر: Molecular metabolism, 6 (9
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 9, Pp 1024-1039 (2017)مصطلحات موضوعية: 0301 basic medicine, Obstétrique, IAPP, islet amyloid polypeptide, uORF, upstream open reading frame, PERK, PKR-like ER kinase, Cell, Eukaryotic Initiation Factor-2, Apoptosis, PBA, 4-phenyl butyric acid, Review, hESC, human embryonic stem cell, Endoplasmic Reticulum, ATF, activating transcription factor, ERAD, ER-associated degradation, eIF-2 Kinase, UPR, unfolded protein response, Gynécologie, Insulin-Secreting Cells, GCN2, general control non-derepressible-2, hiPSC, human induced pluripotent stem cell, Insulin, Pancreatic β cell, Phosphorylation, IER3IP1, immediate early response-3 interacting protein-1, Cell Death, Chemistry, MEHMO, mental retardation, epilepsy, hypogonadism and -genitalism, microcephaly and obesity, Diabetes, GIP, glucose-dependent insulinotropic polypeptide, TUDCA, taurine-conjugated ursodeoxycholic acid derivative, CReP, constitutive repressor of eIF2α phosphorylation, NRF2, nuclear factor, erythroid 2 like 2, Endoplasmic Reticulum Stress, SERCA, sarcoendoplasmic reticulum Ca2+ ATPase, 3. Good health, PP1, protein phosphatase 1, WFS, Wolfram syndrome, medicine.anatomical_structure, XBP1, X-box binding protein 1, CRISPR, clustered regularly interspaced short palindromic repeats, Endoplasmic reticulum stress, PDX1, Signal transduction, Signal Transduction, IRE1, inositol-requiring protein-1, Islet, lcsh:Internal medicine, medicine.medical_specialty, Programmed cell death, SERCA, XBP1, eIF2α, CHOP, C/EBP homologous protein, eIF2, eukaryotic translation initiation factor 2, ER, endoplasmic reticulum, 03 medical and health sciences, Internal medicine, medicine, Diabetes Mellitus, Animals, Humans, HRI, heme-regulated inhibitor kinase, GLP-1, glucagon-like peptide 1, PPA, phenylpropenoic acid glucoside, lcsh:RC31-1245, GWAS, genome-wide association study, Molecular Biology, PKR, protein kinase RNA, ISR, integrated stress response, RyR2, type 2 ryanodine receptor/Ca2+ release channel, Endoplasmic reticulum, Cell Biology, Pdx1, pancreatic duodenal homeobox 1, 030104 developmental biology, Endocrinology, hPSC, human pluripotent stem cell, Cancer research, Unfolded protein response, Unfolded Protein Response, RIDD, regulated IRE1-dependent decay, Biologie cellulaire, MODY, maturity-onset diabetes of the young, HNF1A, hepatocyte nuclear factor 1-α
وصف الملف: 1 full-text file(s): application/pdf
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المؤلفون: Joanna Somers, Tuija Pöyry, Anne E. Willis
المصدر: The International Journal of Biochemistry & Cell Biology
مصطلحات موضوعية: Untranslated region, uORF, upstream open reading frame, Five prime untranslated region, NMD, nonsense mediated decay, Eif, eukaryotic initiation factor, Biology, Biochemistry, Upstream open reading frame, Article, Open Reading Frames, THPO, thrombopoietin, Protein biosynthesis, Animals, Humans, Disease, IRES, internal ribosome entry segment, Codon, Peptide Chain Initiation, Translational, Genetics, Mammals, Messenger RNA, Models, Genetic, RNA, EMCV, encephalomyocarditis virus, Translational control, Cell Biology, SNP, single nucleotide polymorphism, AdoMetDCS, adenosyl-methionine decarboxylase, 4EBPs, 4E-binding proteins, RRL, rabbit reticulocyte lysate, Internal ribosome entry site, Open reading frame, UTR, untranslated region, Protein synthesis, uORF