المؤلفون: Kai‐Yu Zheng, Bo Gao, Hua‐Jie Wang, Jin‐Gang He, Hong‐Sheng Chen, Zhuang‐Li Hu, Li‐Hong Long, Jian‐Guo Chen, Fang Wang

المصدر: Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)

مصطلحات موضوعية: gut microbiota, melatonin, menopausal depression, tryptophans, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2198-3844

URL الوصول: https://doaj.org/article/63ef77a8a78444a9a39f09c3bc6d5ed8

المؤلفون: Shuaihua Gao, Xin Ting Wu, Wenju Zhang, Tyre Richardson, Samuel L. Barrow, Christian A. Thompson-Kucera, Anthony T. Iavarone, Judith P. Klinman

مصطلحات موضوعية: Biophysics, Biochemistry, Neuroscience, Mental Health, Computational Biology, Chemical Sciences not elsewhere classified, tim barrel family, stokes shift decays, specific tryptophan mutants, significantly elevated value, rapid (> ns, exposed region near, established kinetic parameters, earlier reported impact, modified protein devoid, active site residues, enthalpic activation barrier, native tryptophans reside, related solvation dynamics, installed trp displays, (<, native kinetic behavior, native tryptophans, solvation dynamics, single site, protein restructuring, >< sub, thermal activation, k <, e <

Relation: https://figshare.com/articles/journal_contribution/Temporal_Resolution_of_Activity-Related_Solvation_Dynamics_in_the_TIM_Barrel_Enzyme_Murine_Adenosine_Deaminase/25393308

الاتاحة: https://doi.org/10.1021/acscatal.3c02687.s001

المؤلفون: Monnie, Christina M., Hernández Morales, Iker, Meléndez Pacheco, Raixie, Bhinderwala, Fatema, Soloshonok, Vadim A., Gronenborn, Angela M., Landa Álvarez, Aitor, Oyarbide Garmendia, Juan Miguel

مصطلحات موضوعية: fluorinated tryptophans, amino acid synthesis, gramines coupling, protein 19F NMR

وصف الملف: application/pdf

Relation: Advanced Synthesis & Catalysis : (2024); http://hdl.handle.net/10810/68415

الاتاحة: http://hdl.handle.net/10810/68415
https://doi.org/10.1002/adsc.202400031

المؤلفون: Subhrajit Mohanty, Smruti Snigdha Mishra, Kuldeep, Jitendra Maharana, Usharani Subuddhi

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Biotechnology, Immunology, Cancer, Hematology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, various biological macromolecules, tryptophan fluorescence behavior, three discrete stages, normal serum concentration, human serum albumin, effective pharmaceutical formulations, current study deals, two serum albumins, lower concentrations range, like activity assay, double tryptophan proteins, bovine serum albumin, submicellar concentrations, study suggests, micromolar range, two tryptophans, two proteins, triggered research, sodium deoxycholate, proper understanding

Relation: https://figshare.com/articles/journal_contribution/Insight_into_the_Effect_of_Submicellar_Concentrations_of_Sodium_Deoxycholate_on_the_Structure_Stability_and_Activity_of_Bovine_and_Human_Serum_Albumin_An_Interesting_Comparison_between_Single_and_Double_Tryptophan_Proteins/25302585

الاتاحة: https://doi.org/10.1021/acs.langmuir.3c03541.s001
https://figshare.com/articles/journal_contribution/Insight_into_the_Effect_of_Submicellar_Concentrations_of_Sodium_Deoxycholate_on_the_Structure_Stability_and_Activity_of_Bovine_and_Human_Serum_Albumin_An_Interesting_Comparison_between_Single_and_Double_Tryptophan_Proteins/25302585

المؤلفون: Erin Dobrange, Jaime Ricardo Porras-Domínguez, Wim Van den Ende

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Evolutionary Biology, Ecology, Biological Sciences not elsewhere classified, sugars naturally present, structural catalytic pocket, species hosting well, protein multiple sequence, known biocontrol organisms, genomic regions coding, counteract plant diseases, molecular docking ), lysine ), whereas, three intracellular β, fructofuranosidases contain tryptophans, priestia megaterium holds, β ‑ fructofuranosidases, predicted suc6p hydrolases, better discriminate sucrose, priestia megaterium, sacap2 ), predicted sucrose, better understand, suc6p hydrolases, megaterium nbrc15308, megaterium endophytes, widely used

Relation: https://figshare.com/articles/journal_contribution/The_Complex_GH32_Enzyme_Orchestra_from_Priestia_megaterium_Holds_the_Key_to_Better_Discriminate_Sucrose-6-phosphate_Hydrolases_from_Other_Fructofuranosidases_in_Bacteria/24943193

الاتاحة: https://doi.org/10.1021/acs.jafc.3c06874.s001
https://figshare.com/articles/journal_contribution/The_Complex_GH32_Enzyme_Orchestra_from_Priestia_megaterium_Holds_the_Key_to_Better_Discriminate_Sucrose-6-phosphate_Hydrolases_from_Other_Fructofuranosidases_in_Bacteria/24943193

المؤلفون: Dániel Tanács, Róbert Berkecz, Zsolt Bozsó, Gábor K. Tóth, Daniel W. Armstrong, Antal Péter, István Ilisz

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 9, p 4719 (2024)

مصطلحات موضوعية: fluorinated tryptophans analogs, enantioselective separation, core-shell particles, macrocyclic glycopeptide-based chiral stationary phases, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/9/4719; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/a5deda538b894718bfbe64600fd13cf3

الاتاحة: https://doi.org/10.3390/ijms25094719
https://doaj.org/article/a5deda538b894718bfbe64600fd13cf3

المؤلفون: Alexis D. Richaud, Sourav Mandal, Aloke Das, Stéphane P. Roche

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Developmental Biology, Cancer, Mental Health, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, simultaneous paradoxical engagement, iconic folding motif, hairpin peptides capitalizing, gain additional stability, dft calculations support, varying electron densities, tryptophan zipper motif, π interactions within, tryptophan zipper, π interactions, electron density, two pairs, sup ><, strand tryptophans, intricate combination, challenging due, bond donors, >

Relation: https://figshare.com/articles/journal_contribution/Tunable_CH_Interactions_within_a_Tryptophan_Zipper_Motif_to_Stabilize_the_Fold_of_Long_Hairpin_Peptides/24585317

الاتاحة: https://doi.org/10.1021/acschembio.3c00553.s005
https://figshare.com/articles/journal_contribution/Tunable_CH_Interactions_within_a_Tryptophan_Zipper_Motif_to_Stabilize_the_Fold_of_Long_Hairpin_Peptides/24585317

المؤلفون: Sreetama Pal (4989236), Dipayan Bose (385319), Abhijit Chakrabarti (473080), Amitabha Chattopadhyay (293264)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Infectious Diseases, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, observations represent one, imparts mechanical stability, cytoskeletal protein ubiquitous, ankyrin binding domain, spectrin secondary structure, restricted solvation dynamics, optimum cellular function, tryptophan solvation, cellular interior, tetramerization domain, comprehensive domain, urea denaturation, tryptophan dynamics, stark chain, spectrin tryptophans, spectrin organization, spectrin dynamics, segmental mobility, rotational dynamics, results show, plasma membrane, natural progression, metazoan cells

Relation: https://figshare.com/articles/journal_contribution/Comparative_Analysis_of_Tryptophan_Dynamics_in_Spectrin_and_Its_Constituent_Domains_Insights_from_Fluorescence/17099559

الاتاحة: https://doi.org/10.1021/acs.jpcb.1c08600.s001

المؤلفون: Elisabetta Rossi, Valentina Pirovano, Marco Negrato, Giorgio Abbiati, Monica Dell’Acqua

المصدر: Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 1997-2006 (2015)

مصطلحات موضوعية: constrained tryptophans, Diels–Alder, indoles, tetrahydrocarbazoles, unnatural amino acids, Science, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1860-5397

URL الوصول: https://doaj.org/article/96180fb139e64b1b945945cd2c94b49b

المؤلفون: Michele Mari, Simone Lucarini, Francesca Bartoccini, Giovanni Piersanti, Gilberto Spadoni

المصدر: Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 1991-1998 (2014)

مصطلحات موضوعية: Dehydroalanine, Friedel–Crafts alkylation, indoles, migration, tryptophans, Science, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1860-5397

URL الوصول: https://doaj.org/article/0ca4d70d75a54562bc793409b424cb85

المؤلفون: Rui Zhou, Zhaoping Pan, Yuehua Zhang, Fengbo Wu, Qinglin Jiang, Li Guo

المصدر: Molecules; Volume 22; Issue 5; Pages: 695

مصطلحات موضوعية: three-component reaction, nickel(II) glycinate, β-substituted-tryptophans, convenient

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Organic Chemistry; https://dx.doi.org/10.3390/molecules22050695

الاتاحة: https://doi.org/10.3390/molecules22050695

المؤلفون: Hendrik Gruß, Norbert Sewald

المصدر: Chemistry (Weinheim an Der Bergstrasse, Germany)

مصطلحات موضوعية: Halogenation, tryptophans, 010402 general chemistry, 01 natural sciences, Catalysis, late-stage diversification, chemistry.chemical_compound, Palladium Catalysis | Reviews Showcase, cross-coupling, Aromatic amino acids, palladium catalysis, Amino Acids, chemistry.chemical_classification, Indole test, 010405 organic chemistry, enzymatic halogenation, Biomolecule, Organic Chemistry, Tryptophan, Minireviews, Biological activity, General Chemistry, Combinatorial chemistry, 0104 chemical sciences, Amino acid, chemistry, Stereoselectivity, Minireview, Bioorthogonal chemistry, Peptides

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe0e32a76c034b6053e6228fc6a3042
https://doi.org/10.1002/chem.201903756

المؤلفون: ZORNETTA, IRENE, AZARNIA TEHRAN, DOMENICO, ARRIGONI, GIORGIO, LEKA, ONEDA, ZANOTTI, GIUSEPPE, MONTECUCCO, CESARE, Anniballi, Fabrizio, Bano, Luca, Binz, Thomas

المساهمون: Zornetta, Irene, AZARNIA TEHRAN, Domenico, Arrigoni, Giorgio, Anniballi, Fabrizio, Bano, Luca, Leka, Oneda, Zanotti, Giuseppe, Binz, Thoma, Montecucco, Cesare

مصطلحات موضوعية: NEUROTOXIN TYPE-A, LIGHT-CHAIN, SYNAPTOBREVIN, MEMBRANE, TETANUS, TRYPTOPHANS, SEROTYPES, MOVEMENT, PROTEIN

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/27443638; info:eu-repo/semantics/altIdentifier/wos/WOS:000380023300001; volume:6; journal:SCIENTIFIC REPORTS; http://hdl.handle.net/11577/3228676; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84979268226; www.nature.com/srep/index.html

الاتاحة: http://hdl.handle.net/11577/3228676
https://doi.org/10.1038/srep30257

المؤلفون: Svetlana Rajkumar Maurya, Radhakrishnan Mahalakshmi

المصدر: Biochimica et Biophysica Acta

مصطلحات موضوعية: 0301 basic medicine, Protein Folding, Cm, chemical denaturation mid-point, ΔG0kin, apparent Gibbs free energy of unfolding/folding obtained from folding/unfolding kinetic (chevron plots), VDAC-2, Gating, Biochemistry, RMSD, root mean square deviation, DiPhPC, diphytanoylphosphatidyl choline, ΔG0, apparent Gibbs free energy of unfolding/folding derived from equilibrium chemical denaturation, CD, circular dichroism, Micelles, chemistry.chemical_classification, SAS, solvent accessible surface, biology, Protein Stability, Bilayer, Tryptophan, Rg, radius of gyration, <τ>, tryptophan lifetime, 3. Good health, Amino acid, GdnHCl, guanidine hydrochloride, Thermodynamics, Protein folding, hVDAC-2, human voltage dependent anion channel isoform-2, OMM, outer mitochondrial membrane, Stability, Voltage-dependent anion channel, ME214–216, average of molar ellipticity values between 214–216 nm, Biophysics, Article, RMSF, root mean square fluctuation, 03 medical and health sciences, Residue (chemistry), KSV, Stern-Volmer quenching constant, Humans, WT, wild-type hVDAC-2 protein, Voltage-Dependent Anion Channel 2, DDM, dodecyl β-d-maltoside, Tm-start, start temperature of thermal denaturation, ΔHapp, apparent unfolding cooperativity in thermal denaturation, Tm, mid-point of thermal denaturation, Cell Biology, Protein tertiary structure, m, apparent unfolding/folding cooperativity, Kinetics, Crystallography, 030104 developmental biology, Membrane protein, chemistry, biology.protein, Tryptophans

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2dbf552d3390e98b94a282e3a57a8c4
https://doi.org/10.1016/j.bbamem.2016.09.011

المؤلفون: Díaz Ramos, Lourdes Aranzazú

مصطلحات موضوعية: QH345 Biochemistry, QH301 Biology, Arabidopsis, UVR8, tryptophans, QK Botany

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0165c59eecec4d55ca7aea0eb9e6c6

المؤلفون: Giorgio Abbiati, Valentina Pirovano, Elisabetta Rossi, Marco Negrato, Monica Dell'Acqua

المصدر: Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 1997-2006 (2015)
Beilstein Journal of Organic Chemistry

مصطلحات موضوعية: Stereochemistry, Chemistry, Organic Chemistry, constrained tryptophans, Tryptophan, indoles, Free amino, Full Research Paper, Cycloaddition, lcsh:QD241-441, Hydrolysis, tetrahydrocarbazoles, lcsh:Organic chemistry, Diels–Alder, Diels alder, lcsh:Q, lcsh:Science, unnatural amino acids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4892996f62181d045d0b2cab864ec2
https://doaj.org/article/96180fb139e64b1b945945cd2c94b49b

المؤلفون: Zhaoping Pan, Yuehua Zhang, Qinglin Jiang, Li Guo, Rui Zhou, Fengbo Wu

المصدر: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 5, p 695 (2017)
Molecules; Volume 22; Issue 5; Pages: 695

مصطلحات موضوعية: Base (chemistry), Pharmaceutical Science, chemistry.chemical_element, 010402 general chemistry, 01 natural sciences, Article, Catalysis, Analytical Chemistry, convenient, lcsh:QD241-441, lcsh:Organic chemistry, Nickel, Drug Discovery, Polymer chemistry, Organic chemistry, Physical and Theoretical Chemistry, nickel(II) glycinate, chemistry.chemical_classification, β-substituted-tryptophans, 010405 organic chemistry, Component (thermodynamics), Organic Chemistry, Condensation, three-component reaction, Tryptophan, Stereoisomerism, Hydrogen-Ion Concentration, 0104 chemical sciences, chemistry, Chemistry (miscellaneous), Molecular Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba987804dd86da61b0324aa484b01a3
http://europepmc.org/articles/PMC6154671

المؤلفون: Ina L. Urbatsch, Douglas J. Swartz, Joachim Weber

المصدر: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828:1159-1168

مصطلحات موضوعية: Models, Molecular, Drug binding sites, Membrane bilayer, Antifungal Agents, Saccharomyces cerevisiae, Mutant, Molecular Conformation, Biophysics, Plasma protein binding, P-glycoprotein, Biology, Crystallography, X-Ray, Biochemistry, Article, Tacrolimus, Cell membrane, Drug Resistance, Fungal, medicine, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Binding site, Adenosine Triphosphatases, Binding Sites, Valinomycin, Dose-Response Relationship, Drug, Cell Membrane, Tryptophan, Conservative tryptophan substitutions, Polyspecificity, Cell Biology, biology.organism_classification, Native tryptophans, medicine.anatomical_structure, Verapamil, Mutation, Cyclosporine, biology.protein, Intracellular, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc0d3a94567a0df545d057b72a05f06
https://doi.org/10.1016/j.bbamem.2012.12.005

المؤلفون: Zhang, Xiang-Zhi, Deng, Yu-Hua, Yan, Xu, Yu, Ke-Yin, Wang, Fang-Xin, Ma, Xiao-Yan, Fan, Chun-An

المساهمون: Fan, CA (reprint author), Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, 222 Tianshui Nanlu, Lanzhou 730000, Peoples R China., Fan, CA (reprint author), Peking Univ, State Key Lab Nat & Biomimet Drugs, 38 Xueyuan Lu, Beijing 100191, Peoples R China., Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, 222 Tianshui Nanlu, Lanzhou 730000, Peoples R China., Peking Univ, State Key Lab Nat & Biomimet Drugs, 38 Xueyuan Lu, Beijing 100191, Peoples R China., Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China.

المصدر: EI ; SCI

مصطلحات موضوعية: ALPHA-AMINO-ACIDS, PHASE-TRANSFER CATALYSIS, BETA-SUBSTITUTED TRYPTOPHANS, RING-OPENING REACTIONS, ASYMMETRIC-SYNTHESIS, INHIBITORY-ACTIVITY, EXPEDIENT ACCESS, DERIVATIVES, ALKYLATION, GLYCINE

Relation: JOURNAL OF ORGANIC CHEMISTRY.2016,81(13),5655-5662.; 1432862; http://hdl.handle.net/20.500.11897/492051; WOS:000379456500041

الاتاحة: https://hdl.handle.net/20.500.11897/492051
https://doi.org/10.1021/acs.joc.6b00390

المؤلفون: Martino Bolognesi, Alessandra Corazza, Gennaro Esposito, Benedetta Bolognesi, Stefano Ricagno, Sofia Giorgetti, Vittorio Bellotti, Elena Betto, Paolo Viglino, Giampaolo Merlini, Monica Stoppini, Sara Raimondi, Federico Fogolari, Devrim Gumral, Enrico Rennella, Maria Chiara Mimmi, Carlo Pucillo

المصدر: Journal of Molecular Biology. 378:887-897

مصطلحات موضوعية: Models, Molecular, Protein Structure, Amyloid, Protein Folding, NMR and X-ray structure determination, Nuclear Magnetic Resonance, Population, β2-microglobulin, amyloid, fibrillogenesis, role of tryptophans in β2-microglobulin, Circular Dichroism, Crystallography, X-Ray, Kinetics, Microscopy, Electron, Transmission, Nuclear Magnetic Resonance, Biomolecular, Protein Structure, Tertiary, Solutions, Tryptophan, beta 2-Microglobulin, Virology, Electron, Protein structure, Models, Structural Biology, MHC class I, Transmission, education, Beta (finance), Molecular Biology, Microscopy, education.field_of_study, Crystallography, biology, Beta-2 microglobulin, Chemistry, Molecular, Fibrillogenesis, Biochemistry, X-Ray, Biophysics, biology.protein, Protein folding, Tertiary, Biomolecular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea41cdc9cfa5be9bfafd42dff18a00c9
https://doi.org/10.1016/j.jmb.2008.03.002