المؤلفون: Min Lei, Xiying Guo, Yue Yao, Ting Shu, Zhanhong Ren, Xiaosong Yang, Changhan Ouyang, Qingjie Chen, Chao Liu, Xiufen Liu

المصدر: Experimental Gerontology, Vol 182, Iss , Pp 112307- (2023)

مصطلحات موضوعية: Trelagliptin, Diabetes mellitus, Cognitive impairment, Learning and memory, Inflammation, Synaptic plasticity, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0531556523002280; https://doaj.org/toc/1873-6815

URL الوصول: https://doaj.org/article/1a5ea646e289413fbf2c0f9d1f340fcf

المؤلفون: Zeng, S., Dou, W., Li, M., Zhou, Yang, 1989, Guo, J., Zhao, N., Huang, H., Zhou, Q., Hu, W., Ma, Y., Zhao, X., Xie, H.

المصدر: ChemMedChem. 15(16):1608-1617

مصطلحات موضوعية: biostability, DPP-IV, in silico testing, inhibitors, metabolism, 2 [[2 (3 aminopiperidin 1 yl) 4 oxo 6 (1h pyrazol 4 yl)thieno[3, 2 d]pyrimidin 3(4h) yl]methyl] 4 fluorobenzonitrile, 2 [[2 (3 aminopiperidin 1 yl) 4 oxo 6 (pyridin 3 yl)thieno[3, 2 [[2 (3 aminopiperidin 1 yl) 4 oxo 6 (pyridin 4 yl)thieno[3, 2 [[2 (3 aminopiperidin 1 yl) 4 oxo 6 [3 (trifluoromethyl)phenyl]thieno[3, 2 [[2 (3 aminopiperidin 1 yl) 4 oxo 7 (pyridin 3 yl)thieno[3, 2 [[2 (3 aminopiperidin 1 yl) 4 oxothieno[3, 2 [[2 (3 aminopiperidin 1 yl) 6 (2 methoxypyridin 4 yl) 4 oxothieno[3, 2 [[2 (3 aminopiperidin 1 yl) 6 (2 methylpyridin 4 yl) 4 oxothieno[3, 2 [[2 (3 aminopiperidin 1 yl) 6 (3 fluorophenyl) 4 oxothieno[3, 2 [[2 (3 aminopiperidin 1 yl) 6 (3, 5 dimethylisoxazol 4 yl) 4 oxothieno[3, 2 [[2 (3 aminopiperidin 1 yl) 6 (4 fluorophenyl) 4 oxothieno[3, 2 [[2 (3 aminopiperidin 1 yl) 6 bromo 4 oxothieno[3, 2 [[2 (3 aminopiperidin 1 yl) 6 [3 (methylsulfonyl)phenyl] 4 oxothieno[3, 2 [[2 (3 aminopiperidin 1 yl) 7 bromo 4 oxothieno[3, 2 [[2 (3 aminopiperidin 1 yl) 7 fluoro 4 oxothieno[3, 2 [[2 (3 aminopiperidin 1 yl) 7 methyl 4 oxo 6 (pyridin 3 yl)thieno[3, 2 [[2 (3 aminopiperidin 1 yl) 7 methyl 4 oxothieno[3, antidiabetic agent, cytochrome P450, dipeptidyl peptidase IV inhibitor, long acting drug, pyrimidine derivative, trelagliptin, unclassified drug, xanthine derivative, animal experiment, area under the curve, Article, computer model, controlled study, drug bioavailability, drug design, drug efficacy, drug half life, drug potency, drug transformation, glycemic control, IC50, in vitro study, in vivo study, infant, male, maximum plasma concentration, mean residence time, metabolic stability, nonhuman, priority journal, rat, time to maximum plasma concentration

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-286487
https://doi.org/10.1002/cmdc.202000175

المؤلفون: D.A., Urunbaeva, D.K., Najmutdinova, N.G., Sadikova, S.S. , Gulomov

المصدر: Scholastic: Journal of Natural and Medical Education; Vol. 2 No. 6 (2023): Scholastic: Journal of Natural and Medical Education; 202-209

مصطلحات موضوعية: type 2 diabetes mellitus, dipeptidyl peptidase-4 inhibitors, safety, trelagliptin, vildagliptin

وصف الملف: application/pdf

Relation: https://univerpubl.com/index.php/scholastic/article/view/2174/1898; https://univerpubl.com/index.php/scholastic/article/view/2174

الاتاحة: https://univerpubl.com/index.php/scholastic/article/view/2174

المؤلفون: Kohei Kaku, Kazuyuki Ishida, Kohei Shimizu, Meguru Achira, Yuusuke Umeda

المصدر: Journal of Diabetes Investigation, Vol 11, Iss 2, Pp 373-381 (2020)

مصطلحات موضوعية: Chronic kidney failure, Trelagliptin, Type 2 diabetes mellitus, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2040-1116; https://doaj.org/toc/2040-1124

URL الوصول: https://doaj.org/article/938dabafc6de4fc0bd13629af2ba05e3

المؤلفون: Chunnuan Wu, Huining Liu, Shuang Yu, Congcong Ren, Jie Zhang, Guopeng Wang, Bole Li, Yang Liu

المصدر: Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113509- (2022)

مصطلحات موضوعية: Trelagliptin, Omarigliptin, Renal impairment simulation, DPP-4 occupancy, PBPK-DO model, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S0753332222008988; https://doaj.org/toc/0753-3322; https://doaj.org/article/e37af1096b6c4dbba1e5bb882ac164fe

الاتاحة: https://doi.org/10.1016/j.biopha.2022.113509
https://doaj.org/article/e37af1096b6c4dbba1e5bb882ac164fe

المؤلفون: Haiyu Shao, Renzheng Wu, Li Cao, Haifeng Gu, Fang Chai

المصدر: Bioengineered, Vol 12, Iss 1, Pp 960-968 (2021)

مصطلحات موضوعية: osteoporosis, trelagliptin, osteoblastic differentiation, runx2, ampk, mc3t3-e1, Biotechnology, TP248.13-248.65

Relation: http://dx.doi.org/10.1080/21655979.2021.1900633; https://doaj.org/toc/2165-5979; https://doaj.org/toc/2165-5987; https://doaj.org/article/69c677af38184f63a72d1b6cd5866273

الاتاحة: https://doi.org/10.1080/21655979.2021.1900633
https://doaj.org/article/69c677af38184f63a72d1b6cd5866273

المؤلفون: Zhenhua Liu, Lanting Xu, Meimei Xing, Xiaojie Xu, Jinfeng Wei, Jinmei Wang, Wenyi Kang

المصدر: Biomedicine & Pharmacotherapy, Vol 125, Iss , Pp 109952- (2020)

مصطلحات موضوعية: Trelagliptin succinate, Insulin resistance, Adipokines, Glucose intake, PI-3K/Akt, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S0753332220301426; https://doaj.org/toc/0753-3322; https://doaj.org/article/5591d0f231ee4effb6844eb88b350b11

الاتاحة: https://doi.org/10.1016/j.biopha.2020.109952
https://doaj.org/article/5591d0f231ee4effb6844eb88b350b11

المؤلفون: K. Durga Malleswar1, B. Venugopala Rao*1, K. Venkateswara Rao1, S.Shylaja2.

مصطلحات موضوعية: Trelagliptin, Enantiomeric Separation, HPLC, Amylose Based Stationary Phase and Validation

Relation: https://zenodo.org/communities/iajpr; https://doi.org/10.5281/zenodo.3559497; https://doi.org/10.5281/zenodo.3559498; oai:zenodo.org:3559498

الاتاحة: https://doi.org/10.5281/zenodo.3559498

المؤلفون: Inagaki, Nobuya, Sano, Hiroki, Seki, Yoshifumi, Kuroda, Shingo, Kaku, Kohei

المساهمون: 稲垣, 暢也, 30241954

مصطلحات موضوعية: Once-weekly dipeptidyl peptidase-4 inhibitor, Trelagliptin, Type 2 diabetes mellitus

وصف الملف: application/pdf

Relation: http://hdl.handle.net/2433/230434; Journal of Diabetes Investigation; 354; 359

الاتاحة: http://hdl.handle.net/2433/230434

المؤلفون: Masatoshi Yamada, Ryoji Tsuruoka, Masahiro Takasuga, Kotaro Yamaguchi, Mitsuhisa Yamano, Kenichi Uno, Hirano Sayuri

المصدر: Organic Process Research & Development. 25:327-336

مصطلحات موضوعية: Serine protease, biology, 010405 organic chemistry, Organic Chemistry, Enantioselective synthesis, Pharmacology, 010402 general chemistry, Highly selective, 01 natural sciences, 0104 chemical sciences, chemistry.chemical_compound, chemistry, biology.protein, Physical and Theoretical Chemistry, health care economics and organizations, Alogliptin, Trelagliptin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3c8193a4dec04088c61ed3760bbffc5e
https://doi.org/10.1021/acs.oprd.0c00544

المؤلفون: Renzheng Wu, Haifeng Gu, Fang Chai, Haiyu Shao, Li Cao

المصدر: Bioengineered, Vol 12, Iss 1, Pp 960-968 (2021)
Bioengineered
article-version (VoR) Version of Record

مصطلحات موضوعية: 0301 basic medicine, musculoskeletal diseases, Osteoporosis, trelagliptin, Core Binding Factor Alpha 1 Subunit, Bioengineering, AMP-Activated Protein Kinases, Applied Microbiology and Biotechnology, Cell Line, ampk, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, stomatognathic system, medicine, Animals, Osteopontin, Uracil, mc3t3-e1, Dipeptidyl-Peptidase IV Inhibitors, Osteoblasts, biology, Chemistry, Runt, AMPK, Cell Differentiation, General Medicine, medicine.disease, osteoporosis, RUNX2, 030104 developmental biology, 030220 oncology & carcinogenesis, Osteocalcin, biology.protein, Cancer research, runx2, Alkaline phosphatase, osteoblastic differentiation, TP248.13-248.65, Research Article, Research Paper, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bbcc8dd01abfc69a0a5215494a15184
https://doaj.org/article/69c677af38184f63a72d1b6cd5866273

المؤلفون: Yuusuke Umeda, Kohei Kaku, Kazuyuki Ishida, Kohei Shimizu, Meguru Achira

المصدر: Journal of Diabetes Investigation, Vol 11, Iss 2, Pp 373-381 (2020)
Journal of Diabetes Investigation

مصطلحات موضوعية: Male, medicine.medical_specialty, Chronic kidney failure, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, 030232 urology & nephrology, Renal function, 030209 endocrinology & metabolism, Type 2 diabetes, Placebo, Gastroenterology, Diseases of the endocrine glands. Clinical endocrinology, End stage renal disease, 03 medical and health sciences, 0302 clinical medicine, Trelagliptin, Asian People, Double-Blind Method, Japan, Internal medicine, Diabetes mellitus, Type 2 diabetes mellitus, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Renal Insufficiency, Uracil, Aged, Glycated Hemoglobin, Dipeptidyl-Peptidase IV Inhibitors, business.industry, Incidence (epidemiology), Type 2 Diabetes Mellitus, General Medicine, Articles, Middle Aged, medicine.disease, RC648-665, Clinical Trial, Exercise Therapy, Clinical Science and Care, Treatment Outcome, Diabetes Mellitus, Type 2, Kidney Failure, Chronic, Female, Hemodialysis, business, Diet Therapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8265854650d7627e4d90f5b94d67c82c
https://doaj.org/article/938dabafc6de4fc0bd13629af2ba05e3

المؤلفون: Inagaki, Nobuya, Sano, Hiroki, Seki, Yoshifumi, Kuroda, Shingo, Kaku, Kohei

المساهمون: 稲垣, 暢也, 30241954

مصطلحات موضوعية: Long-term safety and efficacy, Trelagliptin, Type 2 diabetes mellitus

وصف الملف: application/pdf

Relation: http://hdl.handle.net/2433/215204; Journal of Diabetes Investigation; 718; 726

الاتاحة: http://hdl.handle.net/2433/215204

المؤلفون: Xiao-Xia Hu, Jianqing Chen, Guo-Quan Chen, Jia-le Chen, Yiling He

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Type 2 diabetes, Saxagliptin, medicine.disease, law.invention, chemistry.chemical_compound, chemistry, Tolerability, Randomized controlled trial, law, Sitagliptin, Internal medicine, Medicine, Vildagliptin, business, Alogliptin, medicine.drug, Trelagliptin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b7da68d4ebdbad65510df42190e9e587
https://doi.org/10.21203/rs.3.rs-829300/v1

المؤلفون: Hiroshi Itoh, Shingo Matsui, Shu Meguro

المصدر: Current Medical Research and Opinion. 35:2071-2078

مصطلحات موضوعية: Male, medicine.medical_specialty, animal structures, 030204 cardiovascular system & hematology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Piperidines, Surveys and Questionnaires, Internal medicine, Diabetes mellitus, medicine, Humans, In patient, 030212 general & internal medicine, Practice Patterns, Physicians', Uracil, Trelagliptin, Glycated Hemoglobin, Dipeptidyl-Peptidase IV Inhibitors, Physician-Patient Relations, Cross-Over Studies, business.industry, DPP-4 Inhibitors, Type 2 Diabetes Mellitus, Patient Preference, General Medicine, Middle Aged, medicine.disease, Patient preference, Preference, stomatognathic diseases, Diabetes Mellitus, Type 2, chemistry, Female, business, Alogliptin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9350bc85bac65a5cdcf03c567e950565
https://doi.org/10.1080/03007995.2019.1651130

المؤلفون: Michiko Togane, Suzuko Matsumoto, Rie Araki, Kosuke Uemura, Tomoko Yamasaki, Toshiko Mori, Hiroyuki Ito, Emiko Tsugami, Eiji Kusano, Shinichi Antoku, Shigenori Ando, Shinya Nishio

المصدر: Diabetes Research and Clinical Practice. 153:41-48

مصطلحات موضوعية: Male, Drug, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, media_common.quotation_subject, 030209 endocrinology & metabolism, Type 2 diabetes, Medication Adherence, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Diabetes mellitus, Internal medicine, Internal Medicine, Humans, Hypoglycemic Agents, Medicine, In patient, Prospective Studies, 030212 general & internal medicine, Medical prescription, Uracil, Dipeptidyl peptidase-4, Aged, Trelagliptin, Glycemic, media_common, Dipeptidyl-Peptidase IV Inhibitors, business.industry, General Medicine, medicine.disease, Diabetes Mellitus, Type 2, chemistry, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97816dcd5d42196d5ca7b40c23e7d345
https://doi.org/10.1016/j.diabres.2019.05.025

المؤلفون: Hitoshi Ishii, Yuki Suzaki, Shingo Matsui, Yuko Miyata

المصدر: Diabetes Therapy

مصطلحات موضوعية: Quality of life, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Type 2 diabetes, Dipeptidyl peptidase-4 inhibitor, 030204 cardiovascular system & hematology, DTR-QOL, 03 medical and health sciences, chemistry.chemical_compound, Trelagliptin, 0302 clinical medicine, DPP-4 inhibitors, Internal medicine, Internal Medicine, medicine, Clinical endpoint, Dosing, Original Research, Glycemic, Treatment satisfaction, business.industry, Type 2 Diabetes Mellitus, medicine.disease, chemistry, Adherence, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b338aa6a41745a73e7c64fdff8d70d12
https://doi.org/10.1007/s13300-019-0643-1

المؤلفون: Akinobu Nakamura, Hideaki Miyoshi, Hiroshi Nomoto, Kazuno Omori, Kohei Yamamoto, Kota Ono, Kyu Yong Cho, Mayuko Oita, Naoki Manda, Shin Aoki, Tatsuya Atsumi, Yoshio Kurihara

المصدر: Endocrine Journal. 2018, 65(2):141

المؤلفون: Nobuya Inagaki, Yoshifumi Seki, Shingo Kuroda, Kohei Kaku, Hiroki Sano

المصدر: Journal of Diabetes Investigation

مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Dipeptidyl peptidase-4 inhibitor, Hypoglycemia, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Trelagliptin, Diabetes mellitus, Internal medicine, Type 2 diabetes mellitus, Internal Medicine, Humans, Medicine, 030212 general & internal medicine, Uracil, Adverse effect, Aged, Glycemic, Glycated Hemoglobin, Dipeptidyl-Peptidase IV Inhibitors, business.industry, Type 2 Diabetes Mellitus, Articles, General Medicine, Middle Aged, medicine.disease, Clinical Trial, Once-weekly dipeptidyl peptidase-4 inhibitor, Treatment Outcome, Clinical Science and Care, Diabetes Mellitus, Type 2, chemistry, Sitagliptin, Female, business, Once‐weekly dipeptidyl peptidase‐4 inhibitor, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315f95b3055db130d09805ea72d68f82
http://hdl.handle.net/2433/230434

المؤلفون: Haiyu Shao (10323492), Renzheng Wu (10323495), Li Cao (106383), Haifeng Gu (1389309), Fang Chai (2296435)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Biotechnology, Ecology, Developmental Biology, Hematology, Biological Sciences not elsewhere classified, Osteoporosis, Trelagliptin, osteoblastic differentiation, RUNX2, AMPK, MC3T3-E1

Relation: https://figshare.com/articles/dataset/Trelagliptin_stimulates_osteoblastic_differentiation_by_increasing_runt-related_transcription_factor_2_RUNX2_a_therapeutic_implication_in_osteoporosis/14236713

الاتاحة: https://doi.org/10.6084/m9.figshare.14236713.v1